This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
p73 delta Monoclonal Antibody (38C674.2)
catalog :
MA5-16183
quantity :
100 ug
price :
US 474.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
38C674.2

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
Product Type :
Antibody
Product Name :
p73 delta Monoclonal Antibody (38C674.2)
Catalog # :
MA5-16183
Quantity :
100 ug
Price :
US 474.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse, Rat
Applications :
ChIP Assay: 5 ug, Immunocytochemistry: 1:20-1:1,000, Immunohistochemistry (Frozen): 1:20-1:1,000, Immunohistochemistry (Paraffin): 5 ug/mL, Immunoprecipitation: Assay-Dependent, Western Blot: 1-3 ug/mL
Species :
Human, Mouse, Rat
Clone :
38C674.2
Isotype :
IgG1, kappa
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
p73 was identified as a long-lost cousin of tumor suppressor protein, p53 (4). p73 has high homology with p53 as well as with p63, a gene implicated in the maintenance of epithelial stem cells. Significant homology between p53, p63, and p73 (approximately 63% amino acid identity in the DNA-binding domain suggest that they may have overlapping functions in the regulation of gene expression (3). The targeted disruption of p73 gene leads to defects hippocampal dysgenesis, hydrocephalus, chronic inflammation and infections (2). Recently, spilicing variant mRNAs of p73 has been identified in MCF-7, a breast carcinoma cell line. These mRNAs code for variant p73 proteins bearing distinct carboxy-terminal structures suggesting that the carboxy-terminal region of p73 may be important for the functions of this protein (1) It was found p73 to be upregulated in a significant fraction of anaplastic thyroid cancers, whereas it was not detectable in normal thyroid epithelial cells nor in papillary or follicular thyroid cancer.
Immunogen :
Synthetic peptide (LYVGDPARHLAT) of p73 (deltaNp73) protein.
Format :
Liquid
Applications w/Dilutions :
ChIP Assay: 5 ug, Immunocytochemistry: 1:20-1:1,000, Immunohistochemistry (Frozen): 1:20-1:1,000, Immunohistochemistry (Paraffin): 5 ug/mL, Immunoprecipitation: Assay-Dependent, Western Blot: 1-3 ug/mL
Aliases :
deltaNp73; OTTHUMP00000003479; OTTHUMP00000003480; p53-like transcription factor; p53-related protein; P73; RP23-254N4.10; TAp73; TP73; transformation related protein 73; Trp73; Tumor protein p73
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA