NFkB p65 Monoclonal Antibody (112A1021) | Invitrogen MA5-16160 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NFkB p65 Monoclonal Antibody (112A1021)

catalog :

MA5-16160

quantity :

100 ug

price :

US 349.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

112A1021

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 11

Published Application/Species/Dilution	Reference
western blot; human; 1:1000; fig 4d	Jia D, Tan Y, Liu H, Ooi S, Li L, Wright K, et al. Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo. Oncotarget. 2016;7:771-85 pubmed publisher
western blot; human; 1:1000; fig 6	Lee S, Chang J, Wu J, Sheu D. Antineoplastic effect of a novel chemopreventive agent, neokestose, on the Caco-2 cell line via inhibition of expression of nuclear factor-κB and cyclooxygenase-2. Mol Med Rep. 2015;12:1114-8 pubmed publisher
	Gaggianesi M, Turdo A, Chinnici A, Lipari E, Apuzzo T, Benfante A, et al. IL-4 primes the dynamics of breast cancer progression via DUSP4 inhibition.. Cancer Res. 2017;0: pubmed publisher
	Tiwari V, Singh M, Rawat J, Devi U, Yadav R, Roy S, et al. Redefining the role of peripheral LPS as a neuroinflammatory agent and evaluating the role of hydrogen sulphide through metformin intervention. Inflammopharmacology. 2016;24:253-264 pubmed
	Rani A, Roy S, Singh M, Devi U, Yadav R, Gautam S, et al. α-Chymotrypsin regulates free fatty acids and UCHL-1 to ameliorate N-methyl nitrosourea induced mammary gland carcinoma in albino wistar rats. Inflammopharmacology. 2016;24:277-286 pubmed
	Manral C, Roy S, Singh M, Gautam S, Yadav R, Rawat J, et al. Effect of β-sitosterol against methyl nitrosourea-induced mammary gland carcinoma in albino rats. BMC Complement Altern Med. 2016;16:260 pubmed publisher
	Arjumand W, Seth A, Sultana S. Rutin attenuates cisplatin induced renal inflammation and apoptosis by reducing NFκB, TNF-α and caspase-3 expression in wistar rats. Food Chem Toxicol. 2011;49:2013-21 pubmed publisher
	Fouad A, Jresat I. Protective effect of telmisartan against cadmium-induced nephrotoxicity in mice. Life Sci. 2011;89:29-35 pubmed publisher
	Fouad A, Jresat I. Hepatoprotective effect of coenzyme Q10 in rats with acetaminophen toxicity. Environ Toxicol Pharmacol. 2012;33:158-67 pubmed publisher
	Fouad A, Al-Sultan A, Yacoubi M, Gomaa W. Ameliorative effects of telmisartan in diabetic rats with indomethacin-induced gastric ulceration. Eur J Pharmacol. 2010;637:162-70 pubmed publisher
	Fouad A, Al-Sultan A, Refaie S, Yacoubi M. Coenzyme Q10 treatment ameliorates acute cisplatin nephrotoxicity in mice. Toxicology. 2010;274:49-56 pubmed publisher

product information

Product Type :

Antibody

Product Name :

NFkB p65 Monoclonal Antibody (112A1021)

Catalog # :

MA5-16160

Quantity :

100 ug

Price :

US 349.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 0.25-0.5 µg/10^6 cells, Immunohistochemistry (Paraffin): 5 µg/ml, Immunohistochemistry: 5-15 µg/ml, Western Blot: 2-5 µg/ml

Species :

Human, Mouse, Rat

Clone :

112A1021

Isotype :

IgG1, kappa

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

NF-kB (nuclear factor kB) regulates the expression of a large number of genes that play critical roles in apoptosis, viral replication, tumorigenesis, various autoimmune diseases and inflammation. The active nuclear form of the NF-kB transcription factor complex is composed of two DNA binding subunits, NF-kB p65 and p50, both of which share extensive N-terminal sequence homology with the v-rel oncogene product. N-terminal regions of p50 and p65 are critical for DNA binding and help determine the DNA-binding specificities of p50 and p65.

Immunogen :

Synthetic peptide corresponding to amino acids 526-539 (GLLSGDEDFSSIAD) of human NF-kB (p65) protein.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25-0.5 µg/10^6 cells, Immunohistochemistry (Paraffin): 5 µg/ml, Immunohistochemistry: 5-15 µg/ml, Western Blot: 2-5 µg/ml

Aliases :

NFKB3, p65, NF-kappa-B p65delta3, nuclear factor NF-kappa-B p65 subunit, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, transcription factor p65

PubMed References :

20399771, 20510337, 21605616, 21620867, 22222558, 26506421