RANK Monoclonal Antibody (9A725) | Invitrogen MA5-16153 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RANK Monoclonal Antibody (9A725)

catalog :

MA5-16153

quantity :

100 ug

price :

US 480.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9A725

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 5	Wang B, Jin H, Shu B, Mira R, Chen D. Chondrocytes-Specific Expression of Osteoprotegerin Modulates Osteoclast Formation in Metaphyseal Bone. Sci Rep. 2015;5:13667 pubmed publisher
flow cytometry; human	Riegel A, Maurer T, Prior B, Stegmaier S, Heppert V, Wagner C, et al. Human polymorphonuclear neutrophils express RANK and are activated by its ligand, RANKL. Eur J Immunol. 2012;42:975-81 pubmed publisher
	Dong J, Shu G, Yang J, Wang B, Chen L, Gong Z, et al. Mechanistic study on the alleviation of postmenopausal osteoporosis by Lactobacillus acidophilus through butyrate-mediated inhibition of osteoclast activity. Sci Rep. 2024;14:7042 pubmed publisher
	Wu P, Jiao F, Huang H, Liu D, Tang W, Liang J, et al. Morinda officinalis polysaccharide enable suppression of osteoclastic differentiation by exosomes derived from rat mesenchymal stem cells. Pharm Biol. 2022;60:1303-1316 pubmed publisher
	Rauwel B, Degboé Y, Diallo K, Sayegh S, Baron M, Boyer J, et al. Inhibition of Osteoclastogenesis by the RNA-Binding Protein QKI5: a Novel Approach to Protect from Bone Resorption. J Bone Miner Res. 2019;: pubmed publisher
	Murakami A, Matsuda M, Harada Y, Hirata M. Phospholipase C-related, but catalytically inactive protein (PRIP) up-regulates osteoclast differentiation via calcium-calcineurin-NFATc1 signaling. J Biol Chem. 2017;292:7994-8006 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RANK Monoclonal Antibody (9A725)

Catalog # :

MA5-16153

Quantity :

100 ug

Price :

US 480.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Avian, Human, Mouse, Rat

Applications :

Flow Cytometry: 2-4 ug/mL, Immunohistochemistry (Paraffin): 1:10-1:500, Western Blot: 1-2 ug/mL

Species :

Avian, Human, Mouse, Rat

Clone :

9A725

Isotype :

IgG1, kappa

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

RANK is a member of the tumor necrosis factor receptor (TNFR) family. The full length mouse RANK cDNA encodes a type I transmembrane protein with an extracellular and a cytoplasmic domain. The extracellular domain contains two potential N-linked glycosylation sites. RANK shares significant amino acid homology with other members of the TNFR family in its extracellular four cysteine-rich repeats. Human and murine RANK share 81% amino acid identity in their extracellular domains.

Immunogen :

A fusion protein containing amino acid residues 326-616 of human RANK.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 2-4 ug/mL, Immunohistochemistry (Paraffin): 1:10-1:500, Western Blot: 1-2 ug/mL

Aliases :

CD265; FEO; LOH18CR1; loss of heterozygosity, 18, chromosomal region 1; Ly109; mRANK; ODFR; OFE; OPTB7; Osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB2; Rank; receptor activator of NF-kappaB; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; RGD1563614; TNF receptor superfamily member 11a; Tnfrsf11a; TRANCER; TRANCE-R; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator

more info or order :

Invitrogen product webpage