APOE Monoclonal Antibody (4E4) | Invitrogen MA5-16146 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

APOE Monoclonal Antibody (4E4)

catalog :

MA5-16146

quantity :

100 uL

price :

US 524.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4.00E+04

The same clone is also sold as:

MyBioSource: MBS375012
Novus Biologicals: NBP1-49529
ImmuQuest: IQ552

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation

citations: 1

Reference
Zhang M, Gong W, Zhang D, Ji M, Chen B, Chen B, et al. Ageing related thyroid deficiency increases brain-targeted transport of liver-derived ApoE4-laden exosomes leading to cognitive impairment. Cell Death Dis. 2022;13:406 pubmed publisher

product information

Product Type :

Antibody

Product Name :

APOE Monoclonal Antibody (4E4)

Catalog # :

MA5-16146

Quantity :

100 uL

Price :

US 524.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 1:100-1:2,000, Immunocytochemistry: 2-5 ug/mL, Immunoprecipitation: 1:10-1:500, Western Blot: 1:1,000-1:2,000

Species :

Human

Clone :

4.00E+04

Isotype :

IgG1, kappa

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Apo E (Apolipoprotein E) plays an important role in the metabolism of lipids in the plasma, and is also is a constituent of various plasma lipoprotein-lipid particles. The protein is synthesized in liver, brain, spleen, and the kidney, and concentrations are high in interstitial fluids, where it plays a role in distributing cholesterol from cells where cholesterol is in excess to cells which require cholesterol. Apo E also plays an important role in the formation of very low density lipoprotein and chylomicrons. The Apo E gene is located on chromosome 19 at position 19q13. 2.

Immunogen :

Synthetic peptide made to an internal region of human ApoE4 (within residues 100-150).

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:100-1:2,000, Immunocytochemistry: 2-5 ug/mL, Immunoprecipitation: 1:10-1:500, Western Blot: 1:1,000-1:2,000

Aliases :

AD2; AI255918; APOE; apo-E; ApoE4; APOEA; Apolipoprotein; apolipoprotein E; apolipoprotein E3; apolipoprotein E4; Apoprotein; B2G1; BG; LDLCQ5; LPG; MGC1571