Nestin Monoclonal Antibody (10C2), DyLight 488 | Invitrogen MA5-16104 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Nestin Monoclonal Antibody (10C2), DyLight 488

catalog :

MA5-16104

quantity :

100 uL

price :

US 474.00

clonality :

monoclonal

host :

mouse

conjugate :

DyLight488

clone name :

10C2

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 2g	Lee E, Ouzounova M, Piranlioglu R, Ma M, Guzel M, Marasco D, et al. The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20. Oncogene. 2019;38:469-482 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Nestin Monoclonal Antibody (10C2), DyLight 488

Catalog # :

MA5-16104

Quantity :

100 uL

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-Dependent, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Frozen): 1:100-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:1,000-1:5,000

Species :

Human

Clone :

10C2

Isotype :

IgG1, kappa

Storage :

4 C, store in dark

Description :

Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.

Immunogen :

A fragment of the human nestin protein corresponding to residues 1464-1614.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-Dependent, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Frozen): 1:100-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:1,000-1:5,000

Aliases :

AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin

more info or order :

Invitrogen product webpage