This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CIP2A Monoclonal Antibody (2G10), DyLight 550
catalog :
MA5-16084
quantity :
100 uL
price :
US 474.00
clonality :
monoclonal
host :
mouse
conjugate :
DyLight 550
clone name :
2G10

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
CIP2A Monoclonal Antibody (2G10), DyLight 550
Catalog # :
MA5-16084
Quantity :
100 uL
Price :
US 474.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse, Non-human primate, Rat
Applications :
Flow Cytometry: Assay-Dependent, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 0.5-2 ug/mL
Species :
Human, Mouse, Non-human primate, Rat
Clone :
2G10
Isotype :
IgG2b, kappa
Storage :
4 C, store in dark
Description :
Inhibition of protein phosphatase 2A (PP2A) activity has been identified as a prerequisite for the transformation of human cells. The protein, designated Cancerous Inhibitor of PP2A (CIP2A), interacts directly with the oncogenic transcription factor c-Myc, inhibits PP2A activity toward c-Myc serine 62 (S62), and thereby prevents c-Myc proteolytic degradation. In addition to its function in c-Myc stabilization, CIP2A promotes anchorage-independent cell growth and in vivo tumor formation. The oncogenic activity of CIP2A is demonstrated by transformation of human cells by overexpression of CIP2A. Importantly, CIP2A is overexpressed in two common human malignancies, head and neck squamous cell carcinoma (HNSCC) and colon cancer.
Immunogen :
A C-terminal portion of the human p90 protein.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-Dependent, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 0.5-2 ug/mL
Aliases :
AA408511; AU018569; C330027C09Rik; Cancerous inhibitor of PP2A; cancerous inhibitor of protein phosphatase 2A; Cip2a; Kiaa1524; p90; p90 autoantigen; p90 autoantigen homolog; Protein CIP2A; RGD1310335; RIKEN cDNA C330027C09 gene; similar to RIKEN cDNA C330027C09
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA