product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MMP1 Monoclonal Antibody (6A5)
catalog :
MA5-15872
quantity :
100 µL
price :
US 486.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6A5
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig s1b
Solomonov I, Zehorai E, Talmi Frank D, Wolf S, Shainskaya A, Zhuravlev A, et al. Distinct biological events generated by ECM proteolysis by two homologous collagenases. Proc Natl Acad Sci U S A. 2016;113:10884-9 pubmed publisher
image
image 1 :
Invitrogen MA5-15872 image 1
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues (left) and human kidney cancer tissues (right) using MA5-15872 anti-MMP1 antibody with DAB staining.
product information
Product Type :
Antibody
Product Name :
MMP1 Monoclonal Antibody (6A5)
Catalog # :
MA5-15872
Quantity :
100 µL
Price :
US 486.00
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Human
Applications :
ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000
Species :
Human
Clone :
6A5
Isotype :
IgG1
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
Immunogen :
Purified recombinant fragment of human MMP1 expressed in E. Coli.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000
Aliases :
22 kDa interstitial collagenase; 27 kDa interstitial collagenase; CLG; CLGN; Collagenase; collagenase-like A; fibroblast collagenase; Interstitial collagenase; interstitial collagenase A; matrix metallo protease; matrix metallopeptidase 1; matrix metallopeptidase 1 (interstitial collagenase); matrix metallopeptidase 1a; matrix metallopeptidase 1a (interstitial collagenase); matrix metalloprotease 1; matrix metalloproteinase 1; matrix metalloproteinase 1a (interstitial collagenase); Matrix metalloproteinase1; Matrix metalloproteinase-1; Matrix metalloproteinase-1a; McolA; Mcol-A; MMP; MMP1; MMP-1; Mmp1a; MMP-1a; MMPs
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA