AMPK alpha-1 Monoclonal Antibody (2B7) | Invitrogen MA5-15815 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

AMPK alpha-1 Monoclonal Antibody (2B7)

catalog :

MA5-15815

quantity :

100 µL

price :

US 489

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2B7

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 6g	Gyamfi J, Yeo J, Kwon D, Min B, Cha Y, Koo J, et al. Interaction between CD36 and FABP4 modulates adipocyte-induced fatty acid import and metabolism in breast cancer. NPJ Breast Cancer. 2021;7:129 pubmed publisher
western blot; mouse; fig 4	Tian W, Li W, Chen Y, Yan Z, Huang X, Zhuang H, et al. Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy. FEBS Lett. 2015;589:1847-54 pubmed publisher
	Cheng L, Zhu X, Liu Y, Zhu K, Lin K, Li F. ACSL4 contributes to sevoflurane-induced ferroptotic neuronal death in SH-SY5Y cells via the 5' AMP-activated protein kinase/mammalian target of rapamycin pathway. Ann Transl Med. 2021;9:1454 pubmed publisher
	Angé M, Castanares Zapatero D, De Poortere J, Dufeys C, Courtoy G, Bouzin C, et al. α1AMP-Activated Protein Kinase Protects against Lipopolysaccharide-Induced Endothelial Barrier Disruption via Junctional Reinforcement and Activation of the p38 MAPK/HSP27 Pathway. Int J Mol Sci. 2020;21: pubmed publisher
	Huang H, Tian X, Peng X, Huang L, Mei L, Zhan Y, et al. Antifungal itraconazole ameliorates experimental autoimmune encephalomyelitis through a novel mechanism of action. Adv Clin Exp Med. 2020;29:535-545 pubmed publisher
	Xu J, Liu K, Chen T, Zhan T, Ouyang Z, Wang Y, et al. Rotating magnetic field delays human umbilical vein endothelial cell aging and prolongs the lifespan of Caenorhabditis elegans. Aging (Albany NY). 2019;11:10385-10408 pubmed publisher

image

image 1 :

Immunohistochemical analysis of paraffin-embedded ovarian cancer (left) and brain tissues (right) using MA5-15815 anti-PRKAA1 antibody with DAB staining.

product information

Product Type :

Antibody

Product Name :

AMPK alpha-1 Monoclonal Antibody (2B7)

Catalog # :

MA5-15815

Quantity :

100 µL

Price :

US 489

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

ELISA: 1:10,000, Flow Cytometry: 1:200 - 1:400, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:1,000

Species :

Human, Mouse, Non-human primate, Rat

Clone :

2B7

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Immunogen :

Purified recombinant fragment of human PRKAA1 expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Flow Cytometry: 1:200 - 1:400, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:1,000

Aliases :

5'-AMP-activated protein kinase alpha-1 catalytic subunit; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; 63 kDa subunit; AAPK2; ACACA kinase; Acetyl-CoA carboxylase kinase; activated protein kinase; AI194361; AI450832; AL024255; AMP -activate kinase alpha 1 subunit; AMP activated protein kinase; AMP-activated protein kinase, alpha 1 catalytic subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK; AMPK 63 kDa subunit; AMPK alpha 1; AMPK alpha-1 chain; AMPK subunit alpha-1; AMPK subunit pAMPK; AMPK1; AMPK2; AMPKa1; AMPKalpha1; AMPK-alpha-2 chain; C130083N04Rik; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; MGC33776; MGC57364; pAMPK; PRKAA; Prkaa1; PRKAA2; protein kinase; protein kinase AMP-activated catalytic subunit alpha 1; protein kinase, AMP-activated, alpha 1 catalytic subunit; tau-protein kinase PRKAA1

more info or order :

Invitrogen product webpage