APAF1 Monoclonal Antibody (5E11) | Invitrogen MA5-15744 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

APAF1 Monoclonal Antibody (5E11)

catalog :

MA5-15744

quantity :

100 ug

price :

US 464.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5.00E+11

reactivity :

human, mouse, rat

application :

immunocytochemistry

product information

Product Type :

Antibody

Product Name :

APAF1 Monoclonal Antibody (5E11)

Catalog # :

MA5-15744

Quantity :

100 ug

Price :

US 464.00

Clonality :

Monoclonal

Purity :

Antigen affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 0.5 mg/mL

Species :

Human, Mouse, Rat

Clone :

5.00E+11

Isotype :

IgG1, kappa

Storage :

-20 C

Description :

APAF1 gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.

Immunogen :

A peptide corresponding to amino acids near the carboxy terminus of human Apaf1.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 0.5 mg/mL

Aliases :

6230400I06Rik; APAF1; APAF-1; Apaf1l; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; apoptotic protease-activating factor 1; CED4; DKFZp781B1145; fog; forebrain overgrowth; KIAA0413; mKIAA0413