SUZ12 Monoclonal Antibody (2C11) | Invitrogen MA5-15732 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SUZ12 Monoclonal Antibody (2C11)

catalog :

MA5-15732

quantity :

100 uL

price :

US 495.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2C11

The same clone is also sold as:

OriGene: AM06556SU-N

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

citations: 3

Reference
Tewes S, Gueler F, Chen R, Gutberlet M, Jang M, Meier M, et al. Functional MRI for characterization of renal perfusion impairment and edema formation due to acute kidney injury in different mouse strains. PLoS ONE. 2017;12:e0173248 pubmed publisher
Zhong C, Cui K, Wilhelm C, Hu G, Mao K, Belkaid Y, et al. Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment. Nat Immunol. 2016;17:169-78 pubmed publisher
Bouchery T, Kyle R, Camberis M, Shepherd A, Filbey K, Smith A, et al. ILC2s and T cells cooperate to ensure maintenance of M2 macrophages for lung immunity against hookworms. Nat Commun. 2015;6:6970 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SUZ12 Monoclonal Antibody (2C11)

Catalog # :

MA5-15732

Quantity :

100 uL

Price :

US 495.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000

Species :

Human

Clone :

2C11

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

SUZ12 (polycomb protein SUZ12) is a zinc finger gene and has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. SUZ12 is also a component of the PRC2/EED-EZH2 complex which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3 leading to transcriptional repression of the affected target gene. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.

Immunogen :

Purified recombinant fragment of human SUZ12 expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000

Aliases :

2610028O16Rik; AI195385; AU016842; AW536442; chET 9 protein; CHET9; chromatin precipitated E2F target 9 protein; D11Ertd530e; JJAZ1; Joined to JAZF1 protein; Kiaa0160; mKIAA0160; Polycomb protein Suz12; suppressor of zeste 12 homolog; suppressor of zeste 12 homolog (Drosophila); suppressor of zeste 12 protein homolog; Suz12; SUZ12 polycomb repressive complex 2 subunit