Torc2 Monoclonal Antibody (5B10) | Invitrogen MA5-15710 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Torc2 Monoclonal Antibody (5B10)

catalog :

MA5-15710

quantity :

100 uL

price :

US 491.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5B10

The same clone is also sold as:

OriGene: AM06534SU-N

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Khan R, Raza S, Junjvlieke Z, Xiaoyu W, Garcia M, Elnour I, et al. Function and Transcriptional Regulation of Bovine TORC2 Gene in Adipocytes: Roles of C/EBP, XBP1, INSM1 and ZNF263. Int J Mol Sci. 2019;20: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Torc2 Monoclonal Antibody (5B10)

Catalog # :

MA5-15710

Quantity :

100 uL

Price :

US 491.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Non-human primate

Applications :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000

Species :

Human, Non-human primate

Clone :

5B10

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CRTC2, also known as TORC2 (Transducers Of Regulated cAMP Response Element-Binding (CREB)) 2 and the related protein CRTC1 are potent CREB coactivators that are exported from the nucleus in a CRM1-dependent manner via phosphorylation-dependent interactions. Studies suggest that their phosphorylation and nuclear/cytoplasmic shuttling play an important role in the regulation of gluconeogenesis by cAMP. CRTC2 is present in both B and T-lymphocytes and abundantly expressed in the thymus. Its activity is important in regulating the expression of genes involved in cellular energy metabolism while CRTC1 is essential for energy balance and fertility.

Immunogen :

Purified recombinant fragment of human CRTC2 expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000

Aliases :

4632407F12Rik; CREB regulated transcription coactivator 2; CREB-regulated transcription coactivator 2; CRTC2; mTORC2; OTTHUMP00000035255; RGD1308903; TORC2; TORC-2; transducer of CREB protein 2; transducer of regulated cAMP response element-binding protein (CREB) 2; transducer of regulated cAMP response element-binding protein 2