SMAD3 Monoclonal Antibody (5G11) | Invitrogen MA5-15663 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SMAD3 Monoclonal Antibody (5G11)

catalog :

MA5-15663

quantity :

100 uL

price :

US 510.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5G11

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human	Tobar N, Toyos M, Urra C, MÃ©ndez N, Arancibia R, Smith P, et al. c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells. BMC Cancer. 2014;14:640 pubmed publisher
western blot; human	Tobar N, Avalos M, Méndez N, Smith P, Bernabeu C, Quintanilla M, et al. Soluble MMP-14 produced by bone marrow-derived stromal cells sheds epithelial endoglin modulating the migratory properties of human breast cancer cells. Carcinogenesis. 2014;35:1770-9 pubmed publisher
	Metwally M, Bayoumi A, Khan A, Adams L, Aller R, García Monzón C, et al. Copy number variation and expression of exportin-4 associates with severity of fibrosis in metabolic associated fatty liver disease. EBioMedicine. 2021;70:103521 pubmed publisher
	Li M, Huang H, Li L, He C, Zhu L, Guo H, et al. Core transcription regulatory circuitry orchestrates corneal epithelial homeostasis. Nat Commun. 2021;12:420 pubmed publisher
	Vervoort S, Lourenço A, Tufegdzic Vidakovic A, Mocholí E, Sandoval J, Rueda O, et al. SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis. Nucleic Acids Res. 2018;46:9578-9590 pubmed publisher
	Li D, Meng L, Xu T, Su Y, Liu X, Zhang Z, et al. RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system. elife. 2017;6: pubmed publisher

product information

Product Type :

Antibody

Product Name :

SMAD3 Monoclonal Antibody (5G11)

Catalog # :

MA5-15663

Quantity :

100 uL

Price :

US 510.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000

Species :

Human, Mouse

Clone :

5G11

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

SMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Immunogen :

Purified recombinant fragment of human SMAD3 expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000

Aliases :

AU022421; DKFZp586N0721; DKFZp686J10186; hMAD-3; hSMAD3; HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MAD (mothers against decapentaplegic, Drosophila) homolog 3; MAD homolog 3; MAD homolog 3a; mad homolog JV15-2; mad protein homolog; MAD, mothers against decapentaplegic homolog 3; mad3; MAD-3; madh3; madh3a; madh3-A; MGC60396; mMad3; mothers against decapentaplegic homolog 3; mothers against decapentaplegic homolog 3a; mothers against DPP homolog 3; SMA- and MAD-related protein 3; SMAD; Smad 3; SMAD family member 3; SMAD family member 3 L homeolog; SMAD family member 3a; SMAD, mothers against DPP homolog 3; Smad3; smad3.L; smad3a; TGF beta response effector Smad3; TGF-beta response effector Smad3; transcription factor; transcription factor Smad3; wu:fa99e03; XELAEV_18018454mg; XenMLP; Xmad3; XSmad3

more info or order :

Invitrogen product webpage