STAT6 Monoclonal Antibody (7D3) | Invitrogen MA5-15659 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

STAT6 Monoclonal Antibody (7D3)

catalog :

MA5-15659

quantity :

100 uL

price :

US 546.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7D3

The same clone is also sold as:

OriGene: AM06474SU-N

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry

citations: 1

Reference
Fuchs S, Rensing Ehl A, Erlacher M, Vraetz T, Hartjes L, Janda A, et al. Patients with T⁺/low NK⁺ IL-2 receptor γ chain deficiency have differentially-impaired cytokine signaling resulting in severe combined immunodeficiency. Eur J Immunol. 2014;44:3129-40 pubmed publisher

product information

Product Type :

Antibody

Product Name :

STAT6 Monoclonal Antibody (7D3)

Catalog # :

MA5-15659

Quantity :

100 uL

Price :

US 546.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

ChIP Assay: 4 uL/10^6 cells, ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Non-human primate, Rat

Clone :

7D3

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.

Immunogen :

Purified recombinant fragment of human STAT6 expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 4 uL/10^6 cells, ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000

Aliases :

12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT