This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IHOG Monoclonal Antibody (3G8)
catalog :
MA5-15648
quantity :
100 uL
price :
US 491.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3G8

The same clone is also sold as:
reactivity :
fruit fly
application :
western blot, ELISA
product information
Product Type :
Antibody
Product Name :
IHOG Monoclonal Antibody (3G8)
Catalog # :
MA5-15648
Quantity :
100 uL
Price :
US 491.00
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Drosophila, Human
Applications :
ELISA: 1:10,000, Western Blot: 1:500-1:2,000
Species :
Drosophila, Human
Clone :
3G8
Isotype :
IgG1
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
The ihog gene (interference hedgehog), identified by RNA interference in Drosophila cultured cells, encodes a type 1 membrane protein shown here to bind and to mediate response to the active Hedgehog (Hh) protein signal. ihog mutations produce defects characteristic of Hh signaling loss in embryos and imaginal discs, and epistasis analysis places ihog action at or upstream of the negatively acting receptor component, Patched (Ptc). The first of two extracellular fibronectin type III (FNIII) domains of the Ihog protein mediates a specific interaction with Hh protein in vitro, but the second FNIII domain is additionally required for in vivo signaling activity and for Ihog-enhanced binding of Hh protein to cells coexpressing Ptc. Other members of the Ihog family, including Drosophila Boi and mammalian CDO and BOC, also interact with Hh ligands via a specific FNIII domain, thus identifying an evolutionarily conserved family of membrane proteins that function in Hh signal response.
Immunogen :
Purified recombinant fragment of human IHOG expressed in E. Coli.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:10,000, Western Blot: 1:500-1:2,000
Aliases :
CG9211; CG9211-PA; CT26314; Dmel ihog; Dmel CG9211; Dmel_CG9211; GH03927p; Ihog; ihog-PA; interference hedgehog
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA