This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
GSK3B Monoclonal Antibody (3D10)
catalog :
MA5-15597
quantity :
100 uL
price :
US 542.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3D10

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 2
Reference
Zablowsky N, Farack L, Rofall S, Kramer J, Meyer H, Nguyen D, et al. High Throughput FISH Screening Identifies Small Molecules That Modulate Oncogenic lncRNA MALAT1 via GSK3B and hnRNPs. Noncoding RNA. 2023;9: pubmed publisher
Kandigian S, Ethier E, Kitchen R, Lam T, Arnold S, Carlyle B. Proteomic characterization of post-mortem human brain tissue following ultracentrifugation-based subcellular fractionation. Brain Commun. 2022;4:fcac103 pubmed publisher
product information
Product Type :
Antibody
Product Name :
GSK3B Monoclonal Antibody (3D10)
Catalog # :
MA5-15597
Quantity :
100 uL
Price :
US 542.00
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Human, Mouse, Non-human primate, Rat
Applications :
ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000
Species :
Human, Mouse, Non-human primate, Rat
Clone :
3D10
Isotype :
IgG2a
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development and body pattern formation. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. GSK3B is also involved in the Hedgehog, Notch, and insulin signaling pathways.
Immunogen :
Purified recombinant fragment of human GSK3B expressed in E. Coli.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:10,000, Flow Cytometry: 1:200-1:400, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500-1:2,000
Aliases :
7330414F15Rik; 8430431H08Rik; C86142; EC 2.7.11.26; FA; Factor A; fb68h05; fk80d11; glycogen synthase kinase 3; glycogen synthase kinase 3 beta; glycogen synthase kinase 3 beta L homeolog; glycogen synthase kinase 3 beta variant 1; glycogen synthase kinase 3 beta variant 2; glycogen synthase kinase 3 beta variant 3; glycogen synthase kinase 3 beta variant 4; glycogen synthase kinase 3 beta variant 5; glycogen synthase kinase 3 beta, genome duplicate a; glycogen synthase kinase-3 beta; glycogen synthase kinase-3 beta splice variant X1; glycogen synthase kinase-3 beta splice variant X2; glycogen synthase kinase-3 beta splice variant X3; GSK 3 beta; GSK 3B; gsk3; GSK-3; GSK3 beta; GSK-3 beta; GSK-3 beta GSK3B; GSK-3[b]; Gsk3b; GSK-3b; gsk3b.L; gsk3ba; gsk3beta; GSK-3beta; gsk3-beta; GSK3beta isoform; intracellular kinase; pp37; serine/threonine-protein kinase GSK3B; wu:fb68h05; wu:fk80d11; XELAEV_180112401mg; xgsk-3; Xgsk-3 protein
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA