CD73 Monoclonal Antibody (1D7) | Invitrogen MA5-15537 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD73 Monoclonal Antibody (1D7)

catalog :

MA5-15537

quantity :

100 uL

price :

US 542.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1D7

The same clone is also sold as:

OriGene: AM06357SU-N

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 3

Reference
Ivanov A, Danilova T, Kuznetsova A, Popova O, Yanushevich O. Decellularized Matrix Induced Spontaneous Odontogenic and Osteogenic Differentiation in Periodontal Cells. Biomolecules. 2023;13: pubmed publisher
Banijamali M, H xf6 jer P, Nagy Á, H xe5 xe5 g P, Gomero E, Stiller C, et al. Characterizing single extracellular vesicles by droplet barcode sequencing for protein analysis. J Extracell Vesicles. 2022;11:e12277 pubmed publisher
Maisto R, Trotta M, Petrillo F, Izzo S, Cuomo G, Alfano R, et al. Resolvin D1 Modulates the Intracellular VEGF-Related miRNAs of Retinal Photoreceptors Challenged With High Glucose. Front Pharmacol. 2020;11:235 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD73 Monoclonal Antibody (1D7)

Catalog # :

MA5-15537

Quantity :

100 uL

Price :

US 542.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500

Species :

Human

Clone :

1D7

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CD73 (Ecto-5-prime-nucleotidase, 5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. CD73 consists of a dimer of 2 identical 70 kDa subunits bound externally to the plasma membrane by a glycosyl phosphatidyl inositol linkage. CD73 is used as a marker of lymphocyte differentiation. Consequently, a deficiency of CD73 occurs in a variety of immunodeficiency diseases. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from CD73 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. The CD73 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations. Defects in the CD73 gene can lead to the calcification of joints and arteries, and intestinal tuberculosis. Two transcript variants encoding different isoforms of CD73 have been found.

Immunogen :

Purified recombinant fragment of NT5E expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500

Aliases :

2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; NTE; Purine 5-Prime-Nucleotidase