GATA4 Monoclonal Antibody (6H10) | Invitrogen MA5-15532 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GATA4 Monoclonal Antibody (6H10)

catalog :

MA5-15532

quantity :

100 µL

price :

US 457

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6H10

reactivity :

human, mouse, rat

application :

western blot, ELISA, flow cytometry

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 2c	Low B, Lim C, Ding S, Tan Y, Ng N, Krishnan V, et al. Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells. Nat Commun. 2021;12:3133 pubmed publisher
	Chou W, Chen W, Shen C. A common variant in 11q23.3 associated with hyperlipidemia is mediated by the binding and regulation of GATA4. NPJ Genom Med. 2022;7:4 pubmed publisher
	Loo L, Soetedjo A, Lau H, Ng N, Ghosh S, Nguyen L, et al. BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells. Cell Death Dis. 2020;11:378 pubmed publisher
	Pan J, Silva T, Gull N, Yang Q, Plummer J, Chen S, et al. Lineage-Specific Epigenomic and Genomic Activation of Oncogene HNF4A Promotes Gastrointestinal Adenocarcinomas. Cancer Res. 2020;80:2722-2736 pubmed publisher
	Ng N, Jasmen J, Lim C, Lau H, Krishnan V, Kadiwala J, et al. HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells. iScience. 2019;16:192-205 pubmed publisher

product information

Product Type :

Antibody

Product Name :

GATA4 Monoclonal Antibody (6H10)

Catalog # :

MA5-15532

Quantity :

100 µL

Pricing :

US 457

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ChIP assay: 1-3 µL, ELISA: 1:10,000, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Rat

Clone :

6H10

Isotype :

IgG2b

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

GATA4 is a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in the gene encoding GATA4 have been associated with cardiac septal defects.

Immunogen :

Purified recombinant fragment of human GATA4 expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ChIP assay: 1-3 µL, ELISA: 1:10,000, Western Blot: 1:500-1:2,000

Aliases :

ASD2; DNA-binding protein GATA-GT2; GAT4; GATA binding protein 4; GATA4; Gata-4; GATA-binding factor 4; GATA-binding protein 4; MGC126629; TACHD; TOF; Transcription factor GATA-4; VSD1

more info or order :

Invitrogen product webpage