ISL1 Monoclonal Antibody (1H9) | Invitrogen MA5-15515 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ISL1 Monoclonal Antibody (1H9)

catalog :

MA5-15515

quantity :

100 µL

price :

US 458

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1H9

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 3

Reference
Schörnig M, Ju X, Fast L, Ebert S, Weigert A, Kanton S, et al. Comparison of induced neurons reveals slower structural and functional maturation in humans than in apes. elife. 2021;10: pubmed publisher
Qiao H, Guo M, Shang J, Zhao W, Wang Z, Liu N, et al. Herpes simplex virus type 1 infection leads to neurodevelopmental disorder-associated neuropathological changes. PLoS Pathog. 2020;16:e1008899 pubmed publisher
Wang Y, Wang L, Guo Y, Zhu Y, Qin J. Engineering stem cell-derived 3D brain organoids in a perfusable organ-on-a-chip system. RSC Adv. 2018;8:1677-1685 pubmed publisher

image

image 1 :

Confocal immunofluorescence analysis of HEK293 cells trasfected with full-length ISL1-hIgGFc using ISL1 antibody (green). Blue: DRAQ5 fluorescent DNA dye.

image 2 :

Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and cervical carcinoma (right), showing nuclear localization using ISL1 antibody with DAB staining.

product information

Product Type :

Antibody

Product Name :

ISL1 Monoclonal Antibody (1H9)

Catalog # :

MA5-15515

Quantity :

100 µL

Pricing :

US 458

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000

Species :

Human

Clone :

1H9

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Immunogen :

Purified recombinant fragment of human ISL1 expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000

Aliases :

Insulin gene enhancer protein ISL-1; insulin related protein; ISL LIM homeobox 1; Isl1; Isl-1; isl-1 homeobox; ISL1 transcription factor LIM/homeodomain (islet-1); ISL1 transcription factor, LIM/homeodomain; ISL1 transcription factor, LIM/homeodomain 1; isl-1=homeobox; Islet 1; ISLET1; islet-1; Lim-homeodomain protein Islet1

more info or order :

Invitrogen product webpage