product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD37 Monoclonal Antibody (2B8)
catalog :
MA5-15492
quantity :
100 µL
price :
US 458
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2B8
reactivity :
human, mouse
application :
ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 1e
Liu T, Kong W, Tang X, Xu M, Wang Q, Zhang B, et al. The transcription factor Zfp90 regulates the self-renewal and differentiation of hematopoietic stem cells. Cell Death Dis. 2018;9:677 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2e
Lu Z, Hong C, Kong G, Assumpção A, Ong I, Bresnick E, et al. Polycomb Group Protein YY1 Is an Essential Regulator of Hematopoietic Stem Cell Quiescence. Cell Rep. 2018;22:1545-1559 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b
Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4g
Huang Y, Rajappa P, Hu W, Hoffman C, CISSE B, Kim J, et al. A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma. J Clin Invest. 2017;127:1826-1838 pubmed publisher
  • flow cytometry; mouse; fig 3a
Shiba E, Izawa K, Kaitani A, Isobe M, Maehara A, Uchida K, et al. Ceramide-CD300f Binding Inhibits Lipopolysaccharide-induced Skin Inflammation. J Biol Chem. 2017;292:2924-2932 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
Xu Monette Z, Li L, Byrd J, Jabbar K, Manyam G, Maria de Winde C, et al. Assessment of CD37 B-cell antigen and cell of origin significantly improves risk prediction in diffuse large B-cell lymphoma. Blood. 2016;128:3083-3100 pubmed publisher
  • flow cytometry; mouse; tbl s1
Kamachi F, Isshiki T, Harada N, Akiba H, Miyake S. ICOS promotes group 2 innate lymphoid cell activation in lungs. Biochem Biophys Res Commun. 2015;463:739-45 pubmed publisher
  • immunocytochemistry; human
  • immunohistochemistry; human
de Winde C, Zuidscherwoude M, Vasaturo A, van der Schaaf A, Figdor C, van Spriel A. Multispectral imaging reveals the tissue distribution of tetraspanins in human lymphoid organs. Histochem Cell Biol. 2015;144:133-46 pubmed publisher
image
image 1 :
Invitrogen MA5-15492 image 1
Confocal immunofluorescence analysis of methanol-fixed BCBL-1 (left) and L1210 (right) cells using CD37 antibody(green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.
product information
Product Type :
Antibody
Product Name :
CD37 Monoclonal Antibody (2B8)
Catalog # :
MA5-15492
Quantity :
100 µL
Pricing :
US 458
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000
Species :
Human, Mouse
Clone :
2B8
Isotype :
IgG1
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.
Immunogen :
Purified recombinant fragment of CD37 expressed in E. Coli.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:10,000, Immunocytochemistry: 1:200-1:1,000
Aliases :
CD37; CD37 antigen; CD37 molecule; cell differentiation antigen 37; GP52-40; Leukocyte antigen CD37; leukocyte surface antigen CD37; tetraspanin-26; Tspan26; Tspan-26
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA