cAMP Monoclonal Antibody (9H4C4) | Invitrogen MA5-15393 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

cAMP Monoclonal Antibody (9H4C4)

catalog :

MA5-15393

quantity :

100 uL

price :

US 495.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9H4C4

citations: 2

Reference
Eswaramoorthy R, Chang C, Wu S, Wang G, Chang J, Ho M. Sustained release of PTH(1-34) from PLGA microspheres suppresses osteoarthritis progression in rats. Acta Biomater. 2012;8:2254-62 pubmed publisher
Deng J, Lang S, Wylie C, Hammes S. The Xenopus laevis isoform of G protein-coupled receptor 3 (GPR3) is a constitutively active cell surface receptor that participates in maintaining meiotic arrest in X. laevis oocytes. Mol Endocrinol. 2008;22:1853-65 pubmed publisher

product information

Product Type :

Antibody

Product Name :

cAMP Monoclonal Antibody (9H4C4)

Catalog # :

MA5-15393

Quantity :

100 uL

Price :

US 495.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Chemical

Applications :

ELISA: 1:10,000

Species :

Chemical

Clone :

9H4C4

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Cyclic adenosine monophosphate (cAMP) plays a key role as an intracellular second messenger for transduction events that follow a number of extracellular signals. The G-Protein Coupled Receptors (GPCR) is the largest family of cell surface receptors. They can be activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, and other physiological signaling molecules. Typically, the binding of the ligands to its receptor resulting in the activation of G-proteins, in return, activates the effector adenylyl cyclase evoking the production of cAMP. The activation of a protein kinase by cAMP results in the phosphorylation of substrate proteins. Currently successful drugs in marketing have been developed to target these receptors. Among the GPCRs, ~367 receptors are potential drug development targets, but only about 20 have been used to generate therapeutically and commercially successful drugs so far. Because the involvement of cAMP can amplify the response of the ligand binding, the second messenger cAMP has been largely employed to monitor the activation of the GPCR to facilitate the therapeutic drug discovery.

Immunogen :

cAMP, conjugated to KLH

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000

Aliases :

18 kDa cationic antimicrobial protein; Antibacterial peptide FALL-39; Antibacterial peptide LL-37; CAMP; CAP18; CAP-18; Cathelicidin antimicrobial peptide; cathelin-like protein; Cathelin-related antimicrobial peptide; CLP; Cnlp; Cramp; Cyclic AMP; FALL39; FALL-39; FALL-39 peptide antibiotic; HSD26; LL37; MCLP