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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Melan-A Monoclonal Antibody (M2-7C10)
catalog :
MA5-15237
quantity :
500 uL
price :
US 480.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
M2-7C10
reactivity :
African green monkey, human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 28
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:40; loading ...; fig 4g
Patwardhan A, Bardin S, Miserey Lenkei S, Larue L, Goud B, Raposo G, et al. Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes. Nat Commun. 2017;8:15835 pubmed publisher
  • immunohistochemistry; mouse
Pedersen M, Küsters Vandevelde H, Viros A, Groenen P, Sanchez Laorden B, Gilhuis J, et al. Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes. Cancer Discov. 2013;3:458-469 pubmed publisher
  • western blot; human
Shimizu K, Mizuno T, Shinga J, Asakura M, Kakimi K, Ishii Y, et al. Vaccination with antigen-transfected, NKT cell ligand-loaded, human cells elicits robust in situ immune responses by dendritic cells. Cancer Res. 2013;73:62-73 pubmed publisher
  • immunohistochemistry; human; 1:100
Ozluk Y, Kilicaslan I, Kazancioglu R, Demirkesen C, Derin D, Mandel N. Intraglomerular crescentic metastases of malignant melanoma. Hum Pathol. 2011;42:2025-8 pubmed publisher
  • immunohistochemistry; human; 1:400
Eskue K, Prieto V, Malpica A. Cellular blue nevus of the uterus: a case report and review of the literature. Int J Gynecol Pathol. 2010;29:583-6 pubmed publisher
  • immunohistochemistry; human; 1:200
Choi W, Miyamura Y, Wolber R, Smuda C, Reinhold W, Liu H, et al. Regulation of human skin pigmentation in situ by repetitive UV exposure: molecular characterization of responses to UVA and/or UVB. J Invest Dermatol. 2010;130:1685-96 pubmed publisher
  • western blot; human
Hoashi T, Sato S, Yamaguchi Y, Passeron T, Tamaki K, Hearing V. Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein. FASEB J. 2010;24:1616-29 pubmed publisher
  • immunohistochemistry - paraffin section; human
Ryan P, Nguyen V, Gholoum S, Carpineta L, Abish S, Ahmed N, et al. Polypoid PEComa in the rectum of a 15-year-old girl: case report and review of PEComa in the gastrointestinal tract. Am J Surg Pathol. 2009;33:475-82 pubmed publisher
  • flow cytometry; human
  • western blot; human; 1:500
Dissanayake S, Olkhanud P, O Connell M, Carter A, French A, Camilli T, et al. Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation. Cancer Res. 2008;68:10205-14 pubmed publisher
  • western blot; African green monkey
Hosoi A, Takeda Y, Sakuta K, Ueha S, Kurachi M, Kimura K, et al. Dendritic cell vaccine with mRNA targeted to the proteasome by polyubiquitination. Biochem Biophys Res Commun. 2008;371:242-6 pubmed publisher
  • immunocytochemistry; human; 1:100
Yamaguchi Y, Coelho S, Zmudzka B, Takahashi K, Beer J, Hearing V, et al. Cyclobutane pyrimidine dimer formation and p53 production in human skin after repeated UV irradiation. Exp Dermatol. 2008;17:916-24 pubmed publisher
  • immunohistochemistry; human; 1:100
Scheithauer B, Rodriguez F, Spinner R, Dyck P, Salem A, Edelman F, et al. Glomus tumor and glomangioma of the nerve. Report of two cases. J Neurosurg. 2008;108:348-56 pubmed publisher
  • immunohistochemistry; human; 1:1000
Bandyopadhyay D, Curry J, Lin Q, Richards H, Chen D, Hornsby P, et al. Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi. Aging Cell. 2007;6:577-91 pubmed
  • flow cytometry; human
Zhang J, Eguchi J, Kruse C, Gomez G, Fakhrai H, Schroter S, et al. Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics. Clin Cancer Res. 2007;13:566-575 pubmed publisher
  • immunohistochemistry; human
Wankowicz Kalinska A, Mailliard R, Olson K, Graham F, Edington H, Kirkwood J, et al. Accumulation of low-avidity anti-melanocortin receptor 1 (anti-MC1R) CD8+ T cells in the lesional skin of a patient with melanoma-related depigmentation. Melanoma Res. 2006;16:165-74 pubmed
  • immunohistochemistry; human
Arrigo T, Pirazzoli P, de Sanctis L, Leone O, Wasniewska M, Messina M, et al. McCune-Albright syndrome in a boy may present with a monolateral macroorchidism as an early and isolated clinical manifestation. Horm Res. 2006;65:114-9 pubmed
  • immunohistochemistry; human
Luiten R, Kueter E, Mooi W, Gallee M, Rankin E, Gerritsen W, et al. Immunogenicity, including vitiligo, and feasibility of vaccination with autologous GM-CSF-transduced tumor cells in metastatic melanoma patients. J Clin Oncol. 2005;23:8978-91 pubmed
  • immunohistochemistry; human; 1:400
Tadokoro T, Yamaguchi Y, Batzer J, Coelho S, Zmudzka B, Miller S, et al. Mechanisms of skin tanning in different racial/ethnic groups in response to ultraviolet radiation. J Invest Dermatol. 2005;124:1326-32 pubmed
  • immunoprecipitation; human
Hoashi T, Watabe H, Muller J, Yamaguchi Y, Vieira W, Hearing V. MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes. J Biol Chem. 2005;280:14006-16 pubmed
Edgar R, Cook J, Douglas M, Samson A, Viator J. Capture and Isolation of Circulating Melanoma Cells Using Photoacoustic Flowmetry. Methods Mol Biol. 2021;2265:203-212 pubmed publisher
Wang T, Xie S, Luo R, Shi L, Bai P, Wang X, et al. Two novel TSC2 mutations in renal epithelioid angiomyolipoma sensitive to everolimus. Cancer Biol Ther. 2020;21:4-11 pubmed publisher
Cho J, Patel B, Bonala S, Manne S, Zhou Y, Vadrevu S, et al. Notch transactivates Rheb to maintain the multipotency of TSC-null cells. Nat Commun. 2017;8:1848 pubmed publisher
Tiwari R, Geliebter J, Lucchese A, Mittelman A, Kanduc D. Computational peptide dissection of Melan-a/MART-1 oncoprotein antigenicity. Peptides. 2004;25:1865-71 pubmed
Mittelman A, Tiwari R, Lucchese G, Willers J, Dummer R, Kanduc D. Identification of monoclonal anti-HMW-MAA antibody linear peptide epitope by proteomic database mining. J Invest Dermatol. 2004;123:670-5 pubmed
van Oijen M, Bins A, Elias S, Sein J, Weder P, de Gast G, et al. On the role of melanoma-specific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients. Clin Cancer Res. 2004;10:4754-60 pubmed
Biddle D, Evans H, Kemp B, El Naggar A, Harvell J, White W, et al. Intraparenchymal nevus cell aggregates in lymph nodes: a possible diagnostic pitfall with malignant melanoma and carcinoma. Am J Surg Pathol. 2003;27:673-81 pubmed
Georgieva J, Milling A, Orfanos C, Geilen C. Magnetic bead RT-PCR: establishment of a new method for detecting circulating melanoma cells. Melanoma Res. 2002;12:309-17 pubmed
Mortarini R, Borri A, Tragni G, Bersani I, Vegetti C, Bajetta E, et al. Peripheral burst of tumor-specific cytotoxic T lymphocytes and infiltration of metastatic lesions by memory CD8+ T cells in melanoma patients receiving interleukin 12. Cancer Res. 2000;60:3559-68 pubmed
product information
Product Type :
Antibody
Product Name :
Melan-A Monoclonal Antibody (M2-7C10)
Catalog # :
MA5-15237
Quantity :
500 uL
Price :
US 480.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): 1:100-1:200, Immunoprecipitation: 1:50, Western Blot: 1:50-1:100
Species :
Human
Clone :
M2-7C10
Isotype :
IgG2b, kappa
Storage :
4 C
Description :
MART1 is involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Immunogen :
Recombinant hMART-1 protein
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): 1:100-1:200, Immunoprecipitation: 1:50, Western Blot: 1:50-1:100
Aliases :
A930034P04Rik; Antigen LB39-AA; antigen SK29-AA; MART1; MART-1; melan-A; melanoma antigen recognized by T-cells 1; melanoma associated antigen recognized by T-cells 1; MLANA; Protein Melan-A
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA