Phospho-S6 (Ser235, Ser236) Monoclonal Antibody (G.22.6) | Invitrogen MA5-15140 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-S6 (Ser235, Ser236) Monoclonal Antibody (G.22.6)

catalog :

MA5-15140

quantity :

100 µL

price :

US 425.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

G.22.6

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; mouse	Bartolomé A, Guillen C, Benito M. Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic β cell death. Autophagy. 2012;8:1757-68 pubmed publisher
	Marques P, Kamitz A, Bartolomé A, Burillo J, Martínez H, Jimenez B, et al. Essential role of glucokinase in the protection of pancreatic β cells to the glucose energetic status. Cell Death Discov. 2019;5:138 pubmed publisher
	Bartolomé A, García Aguilar A, Asahara S, Kido Y, Guillen C, Pajvani U, et al. MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling. Mol Cell Biol. 2017;37: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-S6 (Ser235, Ser236) Monoclonal Antibody (G.22.6)

Catalog # :

MA5-15140

Quantity :

100 µL

Price :

US 425.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): 1:75, Immunohistochemistry (Paraffin): 1:75, Western Blot: 1:500

Species :

Human, Mouse, Rat

Clone :

G.22.6

Isotype :

IgG

Storage :

-20°C

Description :

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Immunogen :

Synthetic phosphopeptide corresponding to residues surrounding pSer235 and pSer236 of human ribosomal protein S6

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): 1:75, Immunohistochemistry (Paraffin): 1:75, Western Blot: 1:500

Aliases :

(Rp)S6; 40S ribosomal protein S6; air[8]; air8; anon-WO02059370.61; CG10944; CG10944-PA; CG10944-PB; Dmel CG10944; Dmel_CG10944; DS6; hemocytes enlarged; hen; l(1)air[8]; l(1)air8; l(1)hen; LD31286p; lethal(1)aberrant immune response[8]; lethal-(1)-haemocytes enlarged; lethal-aberrant-immune-response-8; M(1)7BC; M(1)7C; minute; minute (1) 7BC; OK/SW-cl.2; OTTHUMP00000021121; OTTHUMP00000021122; Phosphoprotein NP33; pp30; ribosomal protein S6; Rp S6; RP11-513M16.6; RPS6; RpS6-PA; RpS6-PB; RS6; S6; S6 ribosomal protein; S6R; Small ribosomal subunit protein eS6; wu:fa92e06; wu:fb64g06; zgc:92237

more info or order :

Invitrogen product webpage