Phospho-EIF2S1 (Ser51) Monoclonal Antibody (S.674.5) | Invitrogen MA5-15133 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-EIF2S1 (Ser51) Monoclonal Antibody (S.674.5)

catalog :

MA5-15133

quantity :

100 µL

price :

US 375.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

S.674.5

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; fig 3b	Green K, Glineburg M, Kearse M, Flores B, Linsalata A, Fedak S, et al. RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nat Commun. 2017;8:2005 pubmed publisher
western blot; human; fig 2	Sherchand S, Ibana J, Zea A, Quayle A, Aiyar A. The High-Risk Human Papillomavirus E6 Oncogene Exacerbates the Negative Effect of Tryptophan Starvation on the Development of Chlamydia trachomatis. PLoS ONE. 2016;11:e0163174 pubmed publisher
western blot; human; 1:50; fig 7a	Frau Méndez M, Fernández Vega I, Ansoleaga B, Blanco Tech R, Carmona Tech M, Antonio Del Río J, et al. Fatal familial insomnia: mitochondrial and protein synthesis machinery decline in the mediodorsal thalamus. Brain Pathol. 2017;27:95-106 pubmed publisher
western blot; mouse; 1:1000; fig s3a	Shih Y, Hsueh Y. VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation. Nat Commun. 2016;7:11020 pubmed publisher
	Karunarathne W, Molagoda I, Lee K, Choi Y, Yu S, Kang C, et al. Protective Effect of Anthocyanin-Enriched Polyphenols from Hibiscus syriacus L. (Malvaceae) against Ultraviolet B-Induced Damage. Antioxidants (Basel). 2021;10: pubmed publisher
	Mytych J, Sołek P, Będzińska A, Rusinek K, Warzybok A, Tabęcka Łonczyńska A, et al. Towards Age-Related Anti-Inflammatory Therapy: Klotho Suppresses Activation of ER and Golgi Stress Response in Senescent Monocytes. Cells. 2020;9: pubmed publisher
	Bittremieux M, La Rovere R, Schuermans M, Luyten T, Mikoshiba K, Vangheluwe P, et al. Extracellular and ER-stored Ca2+ contribute to BIRD-2-induced cell death in diffuse large B-cell lymphoma cells. Cell Death Discov. 2018;4:101 pubmed publisher
	Dhillon P, Rao C. Rotavirus Induces Formation of Remodeled Stress Granules and P Bodies and Their Sequestration in Viroplasms To Promote Progeny Virus Production. J Virol. 2018;92: pubmed publisher
	Frey T, Forsyth K, Sheehan M, De Haven B, Pevarnik J, Hand E, et al. Ectromelia virus lacking the E3L ortholog is replication-defective and nonpathogenic but does induce protective immunity in a mouse strain susceptible to lethal mousepox. Virology. 2018;518:335-348 pubmed publisher

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product information

Product Type :

Antibody

Product Name :

Phospho-EIF2S1 (Ser51) Monoclonal Antibody (S.674.5)

Catalog # :

MA5-15133

Quantity :

100 µL

Price :

US 375.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Drosophila, Human, Mouse, Non-human primate, Rat

Applications :

Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 1:50, Western Blot: 1:1,000

Species :

Drosophila, Human, Mouse, Non-human primate, Rat

Clone :

S.674.5

Isotype :

IgG

Storage :

-20°C

Description :

EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.

Immunogen :

Synthetic phosphopeptide corresponding to residues surrounding pSer51 of human eIF2alpha

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 1:50, Western Blot: 1:1,000

Aliases :

0910001O23Rik; 2410026C18Rik; 35kDa; EIF2; EIF-2; eIF2 alpha; eIF2 alpha subunit; EIF2A; eIF-2A; eIF2alpha; EIF-2alpha; eIF-2-alpha; EIF2S1; eif2s1b; Eukaryotic translation initiation factor 2 subunit 1; eukaryotic translation initiation factor 2 subunit 1b; eukaryotic translation initiation factor 2 subunit alpha; eukaryotic translation initiation factor 2, subunit 1 alpha; eukaryotic translation initiation factor 2, subunit 1 alpha b; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; eukaryotic translation initiation factor 2A; fb19d01; translation initiation factor subunit; wu:fb19d01

more info or order :

Invitrogen product webpage