EZH2 Monoclonal Antibody (H.547.3) | Invitrogen MA5-15101 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EZH2 Monoclonal Antibody (H.547.3)

catalog :

MA5-15101

quantity :

100 µL

price :

US 445.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

H.547.3

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; 1:200; fig 4b	Cheng Z, Naga Srikanth Garikipati V, Truongcao M, CIMINI M, Huang G, Wang C, et al. Serum-Derived Small Extracellular Vesicles From Diabetic Mice Impair Angiogenic Property of Microvascular Endothelial Cells: Role of EZH2. J Am Heart Assoc. 2021;10:e019755 pubmed publisher
immunocytochemistry; human; fig 4e	Wang J, Cheng P, Pavlyukov M, Yu H, Zhang Z, Kim S, et al. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2. J Clin Invest. 2017;127:3075-3089 pubmed publisher
immunoprecipitation; human; fig 1e western blot; human; fig 1a	Wongtrakoongate P, Riddick G, Fucharoen S, Felsenfeld G. Association of the Long Non-coding RNA Steroid Receptor RNA Activator (SRA) with TrxG and PRC2 Complexes. PLoS Genet. 2015;11:e1005615 pubmed publisher
	Zhang T, Yang L, Ke Y, Lei J, Shen S, Shao S, et al. EZH2-dependent epigenetic modulation of histone H3 lysine-27 contributes to psoriasis by promoting keratinocyte proliferation. Cell Death Dis. 2020;11:826 pubmed publisher

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product information

Product Type :

Antibody

Product Name :

EZH2 Monoclonal Antibody (H.547.3)

Catalog # :

MA5-15101

Quantity :

100 µL

Price :

US 445.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

Western Blot: 1:1,000

Species :

Human, Mouse, Non-human primate, Rat

Clone :

H.547.3

Isotype :

IgG1

Storage :

-20°C

Description :

EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Mutations affecting EZH2 can cause Weaver syndrome (WVS).

Immunogen :

Ezh2 recombinant protein containing human Ezh2 residues 351-453

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

an; enhancer of zeste 2 polycomb repressive complex 2 subunit; enhancer of zeste homolog 2; enhancer of zeste homolog 2 (Drosophila); ENX 1; ENX1; Enx-1; Enx1h; EZH 2; EZH1; EZH2; EZH-2; EZH2b; histone-lysine N-methyltransferase EZH2; KMT6; KMT6A; lysine N-methyltransferase 6; mKIAA4065; OTTHUMP00000213774; OTTHUMP00000213778; OTTHUMP00000213779; OTTHUMP00000213780; WVS; WVS2

more info or order :

Invitrogen product webpage