GFAP Monoclonal Antibody (S.880.0) | Invitrogen MA5-15086 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GFAP Monoclonal Antibody (S.880.0)

catalog :

MA5-15086

quantity :

100 µL

price :

US 425.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S.880.0

reactivity :

human, mouse, rat, pigs

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - free floating section

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; 1:300; loading ...; fig s18a	Kim J, Cho J, Kim S, Kang H, Kim D, Kim V, et al. Brain somatic mutations in MTOR reveal translational dysregulations underlying intractable focal epilepsy. J Clin Invest. 2019;129:4207-4223 pubmed publisher
immunocytochemistry; human; fig 7	Higuchi A, Kao S, Ling Q, Chen Y, Li H, Alarfaj A, et al. Long-term xeno-free culture of human pluripotent stem cells on hydrogels with optimal elasticity. Sci Rep. 2015;5:18136 pubmed publisher
immunohistochemistry - free floating section; mouse; 1:1000	Xu H, Rösler T, Carlsson T, de Andrade A, Fiala O, Höllerhage M, et al. Tau silencing by siRNA in the P301S mouse model of tauopathy. Curr Gene Ther. 2014;14:343-51 pubmed
western blot; mouse; 1:2000	Abazyan S, Yang E, Abazyan B, Xia M, Yang C, Rojas C, et al. Mutant disrupted-in-schizophrenia 1 in astrocytes: focus on glutamate metabolism. J Neurosci Res. 2014;92:1659-68 pubmed publisher
immunocytochemistry; mouse; 1:500	Sbai O, Ould Yahoui A, Ferhat L, Gueye Y, Bernard A, Charrat E, et al. Differential vesicular distribution and trafficking of MMP-2, MMP-9, and their inhibitors in astrocytes. Glia. 2010;58:344-66 pubmed publisher

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product information

Product Type :

Antibody

Product Name :

GFAP Monoclonal Antibody (S.880.0)

Catalog # :

MA5-15086

Quantity :

100 µL

Price :

US 425.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse, Porcine, Rat

Applications :

Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:1,000

Species :

Human, Mouse, Porcine, Rat

Clone :

S.880.0

Isotype :

IgG1

Storage :

-20°C

Description :

GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.

Immunogen :

Native GFAP purified from pig spinal cord

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:1,000

Aliases :

6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen

more info or order :

Invitrogen product webpage