Bcl-W Monoclonal Antibody (F.584.7) | Invitrogen MA5-15076 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Bcl-W Monoclonal Antibody (F.584.7)

catalog :

MA5-15076

quantity :

100 uL

price :

US 420.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

F.584.7

reactivity :

human, mouse, rat

application :

western blot

citations: 3

Reference
Wang J, Zhou Z. Estrogen-dependent activation of NCOA3 couples with p300 and NF-κB to mediate antiapoptotic genes in ER-positive breast cancer cells. Discov Oncol. 2023;14:28 pubmed publisher
Vera M, Morris Hanon O, Nogueiras G, Ripari L, Esquivel M, Perez Castro C, et al. Noxa and Mcl-1 expression influence the sensitivity to BH3-mimetics that target Bcl-xL in patient-derived glioma stem cells. Sci Rep. 2022;12:17729 pubmed publisher
Naert G, Ferré V, Keller E, Slender A, Gibbins D, Fisher E, et al. In vivo and ex vivo analyses of amyloid toxicity in the Tc1 mouse model of Down syndrome. J Psychopharmacol. 2017;:269881117743484 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Bcl-W Monoclonal Antibody (F.584.7)

Catalog # :

MA5-15076

Quantity :

100 uL

Price :

US 420.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Western Blot: 1:1,000

Species :

Human, Mouse, Rat

Clone :

F.584.7

Isotype :

IgG

Storage :

-20 C

Description :

Using a PCR-based strategy, an additional protein with life-promoting activity, designated Bcl-w, has been identified. The protein is highly conserved between mouse and human and is encoded by a gene located near the TCRalpha gene on chromosome 14. Bcl-w is expressed in myeloid cell lines but not in T and B lymphocytes, and can be found in a wide range of tissues. An alternative splicing event in exon 4 results in two transcripts. The first, Bcl-w, encodes a protein of 193 amino acids, and the second, Bcl-w/rox, encodes a protein 333 amino acids in length. The 'rox' portion of Bcl-w/rox shows a striking 66% amino acid sequence identity with the Drosophila rox2 protein; however, the Bcl-w/rox transcript may be expressed at very low levels.

Immunogen :

Synthetic peptide corresponding to residues surrounding alanine 39 of Bcl-w

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

Apoptosis regulator Bcl-W; AW048834; BCL2 like 2; BCL2L2; BCL2-L-2; BCL2-like 2; BCL2-like 2 protein; Bcl-2-like protein 2; Bcl2-like protein 2; BCLW; BCL-W; BCL-WEL; BCL-WS; c98; Gtrgal2; Gtrosa41; Kiaa0271; PPP1R51; protein phosphatase 1, regulatory subunit 51