PU.1 Monoclonal Antibody (E.388.3) | Invitrogen MA5-15064 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PU.1 Monoclonal Antibody (E.388.3)

catalog :

MA5-15064

quantity :

100 µL

price :

US 524

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

E.388.3

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; human; loading ...; fig 2a	Gerlach K, Hwang Y, Nikolaev A, Atreya R, Dornhoff H, Steiner S, et al. TH9 cells that express the transcription factor PU.1 drive T cell-mediated colitis via IL-9 receptor signaling in intestinal epithelial cells. Nat Immunol. 2014;15:676-86 pubmed publisher
	Bah I, Youssef D, Yao Z, McCall C, El Gazzar M. Inhibiting KDM6A Demethylase Represses Long Non-Coding RNA Hotairm1 Transcription in MDSC During Sepsis. Front Immunol. 2022;13:823660 pubmed publisher
	Bah I, Alkhateeb T, Youssef D, Yao Z, McCall C, El Gazzar M. KDM6A Lysine Demethylase Directs Epigenetic Polarity of MDSCs during Murine Sepsis. J Innate Immun. 2022;14:112-123 pubmed publisher
	Yau E, Chen Y, Song C, Webb J, Carillo M, Kawasawa Y, et al. Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages. Immunobiology. 2021;226:152150 pubmed publisher

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product information

Product Type :

Antibody

Product Name :

PU.1 Monoclonal Antibody (E.388.3)

Catalog # :

MA5-15064

Quantity :

100 µL

Price :

US 524

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

ChIP Assay: 2.5 µg/10^6 cells, Immunocytochemistry: 1:150-1:200, Immunohistochemistry (Paraffin): 1:200-1:800, Western Blot: 1:1,000

Species :

Human, Mouse

Clone :

E.388.3

Isotype :

IgG

Storage :

-20°C

Description :

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Synthetic peptide corresponding to the sequence of human PU.1 protein

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 2.5 µg/10^6 cells, Immunocytochemistry: 1:150-1:200, Immunohistochemistry (Paraffin): 1:200-1:800, Western Blot: 1:1,000

Aliases :

31 kDa transforming protein; 31 kDa-transforming protein; 31kDa Transforming Protein; Dis1; Dis-1; hCG_25181; hematopoietic transcription factor PU.1; OF; Pu.1; SFFV proviral integration 1; SFFV proviral integration 1 protein; Sfpi1; Sfpi-1; Spi1; SPI-1; Spi-1 proto-oncogene; SPIA; SPI-A; spleen focus forming virus (SFFV) proviral integration oncogene; spleen focus forming virus (SFFV) proviral integration oncogene spi1; spleen focus forming virus proviral integration oncogene spi1; Tcfpu1; Tfpu.1; Transcription factor PU.1; Transcription Factor spi1

more info or order :

Invitrogen product webpage