Phospho-PKC zeta (Thr410) Monoclonal Antibody (S.447.6) | Invitrogen MA5-15060 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-PKC zeta (Thr410) Monoclonal Antibody (S.447.6)

catalog :

MA5-15060

quantity :

100 µL

price :

US 436.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

S.447.6

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 4f	Koundouros N, Karali E, Tripp A, Valle A, Inglese P, Perry N, et al. Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids. Cell. 2020;181:1596-1611.e27 pubmed publisher
	Mattson A, Begun D, Molstad D, Meyer M, Oursler M, Westendorf J, et al. Deficiency in the phosphatase PHLPP1 suppresses osteoclast-mediated bone resorption and enhances bone formation in mice. J Biol Chem. 2019;294:11772-11784 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-PKC zeta (Thr410) Monoclonal Antibody (S.447.6)

Catalog # :

MA5-15060

Quantity :

100 µL

Price :

US 436.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

Western Blot: 1:1,000

Species :

Human, Mouse, Non-human primate, Rat

Clone :

S.447.6

Isotype :

IgG

Storage :

-20°C

Description :

The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. PKC zeta plays a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function.

Immunogen :

Synthetic phosphopeptide corresponding to residues surrounding pThr410 of human PKC zeta

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

14 - 3 - 3 - zeta isoform; 14-3-3-zetaisoform; AI098070; aPKCzeta; atypical protein kinase C; C80388; kinase nPKC-zeta; KPCZ; nPKC-zeta; nPKC-zeta PRKCZ; PKC2; Pkcz; PKC-ZETA; Prkcz; protein kinase C zeta; protein kinase C zeta subspecies; protein kinase C zeta type; protein kinase C, zeta; r14-3-3; R74924; zetaPKC

more info or order :

Invitrogen product webpage