c-Fos Monoclonal Antibody (T.142.5) | Invitrogen MA5-15055 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

c-Fos Monoclonal Antibody (T.142.5)

catalog :

MA5-15055

quantity :

100 uL

price :

US 524.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

T.142.5

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, flow cytometry

citations: 9

Reference
Coleman D, Keane P, Chin P, Ames L, Kellaway S, Blair H, et al. Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1. iScience. 2024;27:109576 pubmed publisher
Kellaway S, Potluri S, Keane P, Blair H, Ames L, Worker A, et al. Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth. Nat Commun. 2024;15:1359 pubmed publisher
Liskiewicz A, Khalil A, Liśkiewicz D, Novikoff A, Grandl G, Maity Kumar G, et al. Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice. Nat Metab. 2023;5:2075-2085 pubmed publisher
Kumar P, Soory A, Mustfa S, Sarmah D, Devvanshi H, Chatterjee S, et al. Bidirectional regulation between AP-1 and SUMOylation pathway genes modulates inflammatory signaling during Salmonella infection. J Cell Sci. 2022;135: pubmed publisher
Long X, Wu H, Zhou Y, Wan Y, Kan X, Gong J, et al. Preventive Effect of Limosilactobacillus fermentum SCHY34 on Lead Acetate-Induced Neurological Damage in SD Rats. Front Nutr. 2022;9:852012 pubmed publisher
Tang Y, Zong H, Kwon H, Qiu Y, Pessin J, Wu L, et al. TIGAR deficiency enhances skeletal muscle thermogenesis by increasing neuromuscular junction cholinergic signaling. elife. 2022;11: pubmed publisher
Moyo M, Parker J, Chakravarti D. Altered chromatin landscape and enhancer engagement underlie transcriptional dysregulation in MED12 mutant uterine leiomyomas. Nat Commun. 2020;11:1019 pubmed publisher
Carver C, Hastings S, Cook M, Shapiro M. Functional responses of the hippocampus to hyperexcitability depend on directed, neuron-specific KCNQ2 K+ channel plasticity. Hippocampus. 2019;: pubmed publisher
Peli A, Grandis A, Tassinari M, Famigli Bergamini P, Tagliavia C, Roccaro M, et al. Environment and Behavior: Neurochemical Effects of Different Diets in the Calf Brain. Animals (Basel). 2019;9: pubmed publisher

product information

Product Type :

Antibody

Product Name :

c-Fos Monoclonal Antibody (T.142.5)

Catalog # :

MA5-15055

Quantity :

100 uL

Price :

US 524.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ChIP Assay: 1:50, Flow Cytometry: 1:1,600-1:6,400, Immunocytochemistry: 1:3,200-1:12,800, Western Blot: 1:1,000

Species :

Human, Mouse, Rat

Clone :

T.142.5

Isotype :

IgG

Storage :

-20 C

Description :

FBJ murine osteosarcoma viral oncogene homolog is commonly known as Cellular protooncogene Fos (c-Fos). It belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14. c-Fos heterodimerizes with c-Jun to form the Activator Protein -1 (AP-1) transcription factor which regulates transcription of several genes that play an important role in cellular signal transduction, cell proliferation and differentiation. c-Fos has been shown to be phosphorylated by various stimuli including growth factors and insulin at atleast seven different sites. The best known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK which regulates localization of c-Fos to the nucleus and is thus important for c-Fos induced transcriptional activity.

Immunogen :

Synthetic peptide corresponding to the sequence of human c-Fos

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 1:50, Flow Cytometry: 1:1,600-1:6,400, Immunocytochemistry: 1:3,200-1:12,800, Western Blot: 1:1,000

Aliases :

activator protein 1; AP-1; cellular oncogene c-fos; cellular oncogene fos; cFos; C-FOS; c-fos oncogene; c-fos protooncogene protein; D12Rfj1; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS); FBJ murine osteosarcoma viral oncogene homolog; FBJ murine osteosarcoma viral oncogene homolog B; FBJ osteosarcoma oncogene; FBJ osteosarcoma oncogene B; FBJ osteosarcoma viral oncogene isoform deltaFosb-2; FOS; Fos proto-oncogene, AP-1 trancription factor subunit; Fos proto-oncogene, AP-1 transcription factor subunit; Fosb; FosB proto-oncogene, AP-1 transcription factor subunit; fra-2; G0/G1 switch regulatory protein 7; G0S7; I79_009428; p55; protein fosB; proto-oncogene cFOS; proto-oncogene c-Fos; proto-oncogene protein c-fos; v-fos FBJ murine osteosarcoma viral oncogene homolog