TRAF1 Monoclonal Antibody (K.915.10) | Invitrogen MA5-15043 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TRAF1 Monoclonal Antibody (K.915.10)

catalog :

MA5-15043

quantity :

100 µL

price :

US 418

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

K.915.10

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:50; tbl 2	Menter T, Dickenmann M, Juskevicius D, Steiger J, Dirnhofer S, Tzankov A. Comprehensive phenotypic characterization of PTLD reveals potential reliance on EBV or NF-ÎºB signalling instead of B-cell receptor signalling. Hematol Oncol. 2017;35:187-197 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TRAF1 Monoclonal Antibody (K.915.10)

Catalog # :

MA5-15043

Quantity :

100 µL

Pricing :

US 418

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Non-human primate

Applications :

Flow Cytometry: 1:200, Immunocytochemistry: 1:800, Immunohistochemistry (Paraffin): 1:100, Immunoprecipitation: 1:50, Western Blot: 1:1,000

Species :

Human, Non-human primate

Clone :

K.915.10

Isotype :

IgG

Storage :

-20°C

Description :

The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene.

Immunogen :

Synthetic peptide corresponding to residues surrounding cysteine 57 of human TRAF1

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:200, Immunocytochemistry: 1:800, Immunohistochemistry (Paraffin): 1:100, Immunoprecipitation: 1:50, Western Blot: 1:1,000

Aliases :

4732496E14Rik; EBI6; Epstein-Bar virus-induced protein 6; Epstein-Barr virus-induced protein 6; MGC:10353; TNF receptor associated factor 1; TNF receptor-associated factor 1; Traf1

more info or order :

Invitrogen product webpage