GEF-H1 Monoclonal Antibody (K.607.1) | Invitrogen MA5-15027 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GEF-H1 Monoclonal Antibody (K.607.1)

catalog :

MA5-15027

quantity :

100 uL

price :

US 474.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

K.607.1

reactivity :

Chinese hamsters, human, mouse, rat

application :

western blot

citations: 1

Reference
Pan W, Nagpal K, Suárez Fueyo A, Ferretti A, Yoshida N, Tsokos M, et al. The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway. J Immunol. 2021;206:1719-1728 pubmed publisher

product information

Product Type :

Antibody

Product Name :

GEF-H1 Monoclonal Antibody (K.607.1)

Catalog # :

MA5-15027

Quantity :

100 uL

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Hamster, Human, Mouse, Non-human primate, Rat

Applications :

Western Blot: 1:1,000

Species :

Hamster, Human, Mouse, Non-human primate, Rat

Clone :

K.607.1

Isotype :

IgG

Storage :

-20 C

Description :

GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Alternatively spliced transcript variants encoding different isoforms have been identified.

Immunogen :

Synthetic peptide corresponding to the sequence of human GEF-H1

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

AA408978; ARHGEF2; CG10188; CG10188-PA; CG10188-PB; CG10188-PC; cyst; cyst-PA; cyst-PB; cyst-PC; cysts; DKFZp547L106; DKFZp547P1516; Dmel CG10188; Dmel_CG10188; FLJ45440; GEF; GEFH1; GEF-H1; Guanine nucleotide exchange factor H1; Kiaa0651; Lbcl1; LBC'S first cousin; Lfc; LFP40; Lymphoid blast crisis-like 1; microtubule-regulated Rho-GEF; mKIAA0651; oncogene LFC; OTTHUMP00000018855; P40; Proliferating cell nucleolar antigen p40; rho guanine nucleotide exchange factor 2; rho guanine nucleotide exchange factor 2-like protein; Rho/Rac guanine nucleotide exchange factor (GEF) 2; Rho/Rac guanine nucleotide exchange factor 2; rhobin