Catenin alpha-1 Monoclonal Antibody (J.783.6) | Invitrogen MA5-14986 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Catenin alpha-1 Monoclonal Antibody (J.783.6)

catalog :

MA5-14986

quantity :

100 uL

price :

US 414.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

J.783.6

reactivity :

human, mouse

application :

western blot, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

Catenin alpha-1 Monoclonal Antibody (J.783.6)

Catalog # :

MA5-14986

Quantity :

100 uL

Price :

US 414.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate

Applications :

Immunoprecipitation: 1:50, Western Blot: 1:1,000

Species :

Human, Mouse, Non-human primate

Clone :

J.783.6

Isotype :

IgG

Storage :

-20 C

Description :

Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherence junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.

Immunogen :

Synthetic peptide corresponding to the amino-terminal sequence of human a-E-catenin

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: 1:50, Western Blot: 1:1,000

Aliases :

[a]E-catenin; 102 kDa cadherin-associated protein; 2010010M04Rik; AA517462; AI988031; alpha E catenin; alpha E-catenin; alpha(E)-catenin; alpha-E-catenin; cadherin associated protein; Cadherin-associated protein; CAP102; catenin (cadherin associated protein), alpha 1; catenin (cadherin-associated protein), alpha; catenin (cadherin-associated protein), alpha 1; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin alpha 1; catenin alpha 1 S homeolog; catenin alpha-1; catenin, alpha 1; Catna1; cell-adhesion protein alphaE catenin; ctnna; ctnna1; ctnna1.S; MDPT2; Renal carcinoma antigen NY-REN-13; XELAEV_18020018mg