DAXX Monoclonal Antibody (K.180.3) | Invitrogen MA5-14974 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DAXX Monoclonal Antibody (K.180.3)

catalog :

MA5-14974

quantity :

100 uL

price :

US 414.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

K.180.3

reactivity :

human, mouse, rat, dogs, bovine

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

DAXX Monoclonal Antibody (K.180.3)

Catalog # :

MA5-14974

Quantity :

100 uL

Price :

US 414.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Bovine, Canine, Human, Mouse, Non-human primate, Rat

Applications :

Immunocytochemistry: 1:25, Western Blot: 1:500

Species :

Bovine, Canine, Human, Mouse, Non-human primate, Rat

Clone :

K.180.3

Isotype :

IgG

Storage :

-20 C

Description :

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

Immunogen :

Synthetic peptide corresponding to a region surrounding Gln255 of Daxx

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:25, Western Blot: 1:500

Aliases :

BING2; CENP-C binding protein; DADB-159G18.9; DAP6; Daxx; death domain associated protein; Death domain-associated protein 6; death-associated protein 6; death-domain associated protein; EAP1; ETS1-associated protein 1; Fas death domain-associated protein; Fas-binding protein; hDaxx; MGC126245; MGC126246; SMIM40; Unknown (protein for MGC:138055)