TCF7 Monoclonal Antibody (G.452.9) | Invitrogen MA5-14972 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TCF7 Monoclonal Antibody (G.452.9)

catalog :

MA5-14972

quantity :

100 uL

price :

US 444.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

G.452.9

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

TCF7 Monoclonal Antibody (G.452.9)

Catalog # :

MA5-14972

Quantity :

100 uL

Price :

US 444.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:200, Immunoprecipitation: 1:50, Western Blot: 1:1,000

Species :

Human, Mouse, Rat

Clone :

G.452.9

Isotype :

IgG

Storage :

-20 C

Description :

TCF7 (transcriptional factor 7) is a transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ and CD8+ immature thymocytes. Isoforms for TCF7 lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. TCF7 binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. It may also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3, and TLE4 repress transactivation mediated by TCF7 and CTNNB1.

Immunogen :

Synthetic peptide corresponding to a region surrounding Leu160 of human TCF1/TCF7 protein.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:200, Immunoprecipitation: 1:50, Western Blot: 1:1,000

Aliases :

AI465550; HMG-box; OTTHUMP00000159390; OTTHUMP00000159391; T cell factor-1; T-cell factor 1; T-cell specific; T-cell-specific transcription factor 1; Tcf1; TCF-1; Tcf7; TCF-7; Transcription factor 7; transcription factor 7 (T-cell specific, HMG-box); transcription factor 7, T cell specific; transcription factor 7, T-cell specific