Phospho-PDGFRA/PDGFRB (Tyr849, Tyr857) Monoclonal Antibody (T.564.8)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-PDGFRA/PDGFRB (Tyr849, Tyr857) Monoclonal Antibody (T.564.8)

catalog :

MA5-14905

quantity :

100 uL

price :

US 474.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

T.564.8

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation

citations: 6

Reference
Villot R, Poirier A, Bakan I, Boulay K, Fernández E, Devillers R, et al. ZNF768 links oncogenic RAS to cellular senescence. Nat Commun. 2021;12:4841 pubmed publisher
Tai Y, Gallo N, Wang M, Yu J, Van Aelst L. Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron. 2019;102:358-372.e9 pubmed publisher
Sandlesh P, Juang T, Safina A, Higgins M, Gurova K. Uncovering the fine print of the CreERT2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene. PLoS ONE. 2018;13:e0199785 pubmed publisher
Fuentes N, Mlih M, Barhoumi R, Fan Y, Hardin P, Steele T, et al. Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition. Cancer Res. 2018;78:3899-3912 pubmed publisher
Tian H, Tackmann N, Jin A, Zheng J, Zhang Y. Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice. J Biol Chem. 2017;292:21614-21622 pubmed publisher
Liu S, Jiang Y, Ballou L, Zong W, Lin R. Activation of Gαq in Cardiomyocytes Increases Vps34 Activity and Stimulates Autophagy. J Cardiovasc Pharmacol. 2017;69:198-211 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-PDGFRA/PDGFRB (Tyr849, Tyr857) Monoclonal Antibody (T.564.8)

Catalog # :

MA5-14905

Quantity :

100 uL

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunoprecipitation: 1:50, Western Blot: 1:1,000

Species :

Human, Mouse, Rat

Clone :

T.564.8

Isotype :

IgG

Storage :

-20 C

Description :

PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.

Immunogen :

Synthetic phosphopeptide corresponding to residues surrounding pTyr857 of human PDGF receptor ß

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: 1:50, Western Blot: 1:1,000

Aliases :

AI115593; AI528809; alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); alpha-type platelet-derived growth factor receptor; APDGFR; beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140 antigen-like family member B; CD140a; CD140a antigen; CD140b; GAS9; IBGC4; IMF1; JTK12; KOGS; MGC74795; PDGF alpha chain; PDGF beta chain; PDGF Receptor alpha; PDGFACE; PDGFR; PDGFR1; PDGFR-1; PDGFR2; PDGFR-2; Pdgfra; pdgfr-a; PDGFRA/BCR fusion; PDGF-R-alpha; PDGFR-alpha; Pdgfrb; PDGF-R-beta; PDGFR-beta; PENTT; PGFRB; platelet derived growth factor receptor alpha; platelet derived growth factor receptor beta; platelet derived growth factor receptor, alpha polypeptide; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 1; platelet-derived growth factor receptor 2; Platelet-derived growth factor receptor alpha; platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; platelet-derived growth factor receptor, alpha polypeptide; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA