EVI1 Monoclonal Antibody (S.446.4) | Invitrogen MA5-14892 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EVI1 Monoclonal Antibody (S.446.4)

catalog :

MA5-14892

quantity :

100 uL

price :

US 464.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

S.446.4

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 1

Reference
Ng H, Robinson M, May P, Innes A, Hiemeyer C, Feldhahn N. Promoter-centred chromatin interactions associated with EVI1 expression in EVI1+3q- myeloid leukaemia cells. Br J Haematol. 2024;: pubmed publisher

product information

Product Type :

Antibody

Product Name :

EVI1 Monoclonal Antibody (S.446.4)

Catalog # :

MA5-14892

Quantity :

100 uL

Price :

US 464.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Flow Cytometry: 1:800-1:1,600, Immunocytochemistry: 1:1,000-1:2,000, Immunoprecipitation: 1:50, Western Blot: 1:1,000

Species :

Human

Clone :

S.446.4

Isotype :

IgG

Storage :

-20 C

Description :

EVI1 (MECOM) is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, cell differentiation, and proliferation. It can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. The EVI1 gene can undergo translocation with the AML1 gene, resulting in overexpression of the EVI1 gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.

Immunogen :

Synthetic peptide corresponding to residues surrounding Asp57 of human Evi-1

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:800-1:1,600, Immunocytochemistry: 1:1,000-1:2,000, Immunoprecipitation: 1:50, Western Blot: 1:1,000

Aliases :

AML1-EVI-1; AML1-EVI-1 fusion protein; D630039M04Rik; ecotropic viral integration site 1; ecotropic virus integration site 1 protein; Ecotropic virus integration site 1 protein homolog; EVI1; Evi-1; Histone-lysine N-methyltransferase MECOM; Jbo; Mds; MDS1; MDS1 and EVI1 complex locus; MDS1 and EVI1 complex locus protein; MDS1 and EVI1 complex locus protein EVI1; MDS1 and EVI1 complex locus protein MDS1; Mds1-Evi1; Mecom; MGC163392; MGC97004; myelodysplasia syndrome 1 homolog; Myelodysplasia syndrome 1 protein; Myelodysplasia syndrome 1 protein homolog; myelodysplasia syndrome-associated protein 1; oncogene EVI1; OTTHUMP00000213163; OTTHUMP00000213164; OTTHUMP00000213165; OTTHUMP00000213187; OTTHUMP00000213192; PR domain 3; PRDM3; RUSAT2; zinc finger protein Evi1; Znfpr1b1