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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PPAR gamma Monoclonal Antibody (K.242.9)
catalog :
MA5-14889
quantity :
100 uL
price :
US 464.00
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
K.242.9
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 19
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 5e
Bando Y, Tokuda N, Ogasawara Y, Onozawa G, Nagasaka A, Sakiyama K, et al. Expression and enhancement of FABP4 in septoclasts of the growth plate in FABP5-deficient mouse tibiae. Histochem Cell Biol. 2021;155:439-449 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 3a
  • western blot; mouse; loading ...; fig 5e
Dogan A, Demirci S, Apdik H, Bayrak O, Gulluoglu S, Tuysuz E, et al. A new hope for obesity management: Boron inhibits adipogenesis in progenitor cells through the Wnt/β-catenin pathway. Metabolism. 2017;69:130-142 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 7L
Patil M, Sharma B, Elattar S, Chang J, Kapil S, Yuan J, et al. Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning. Diabetes. 2017;66:1611-1625 pubmed publisher
  • immunocytochemistry; mouse; 1:200; loading ...; fig 4
  • western blot; mouse; 1:1000; loading ...; fig 5a
Dogan A, Demirci S, Kıratlı B, Sahin F. Cytoglobin: a potential marker for adipogenic differentiation in preadipocytes in vitro. Cytotechnology. 2017;69:157-165 pubmed publisher
  • western blot; mouse; loading ...; fig 1a
Jacobsen R, Mazloumi Gavgani F, Mellgren G, Lewis A. DNA Topoisomerase II? contributes to the early steps of adipogenesis in 3T3-L1 cells. Cell Signal. 2016;28:1593-603 pubmed publisher
  • western blot; mouse; fig 1
Liu L, Zheng L, Zou P, Brooke J, Smith C, Long Y, et al. FoxO1 antagonist suppresses autophagy and lipid droplet growth in adipocytes. Cell Cycle. 2016;15:2033-41 pubmed publisher
  • western blot; mouse
Liu L, Zou P, Zheng L, Linarelli L, Amarell S, Passaro A, et al. Tamoxifen reduces fat mass by boosting reactive oxygen species. Cell Death Dis. 2015;6:e1586 pubmed publisher
  • western blot; mouse
Zou P, Liu L, Zheng L, Liu L, Stoneman R, Cho A, et al. Targeting FoxO1 with AS1842856 suppresses adipogenesis. Cell Cycle. 2014;13:3759-67 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500
  • immunocytochemistry; mouse; 1:250
Wang W, Kissig M, Rajakumari S, Huang L, Lim H, Won K, et al. Ebf2 is a selective marker of brown and beige adipogenic precursor cells. Proc Natl Acad Sci U S A. 2014;111:14466-71 pubmed publisher
Gou W, Wei H, Swaby L, Green E, Wang H. Deletion of Spinophilin Promotes White Adipocyte Browning. Pharmaceuticals (Basel). 2023;16: pubmed publisher
Fung C, Zhou S, Zhu H, Wei X, Wu Z, Wu A. Cell fate determining molecular switches and signaling pathways in Pax7-expressing somitic mesoderm. Cell Discov. 2022;8:61 pubmed publisher
Suh J, Kim K, Conner M, Moore D, Preidis G. Hepatic PPARα Is Destabilized by SIRT1 Deacetylase in Undernourished Male Mice. Front Nutr. 2022;9:831879 pubmed publisher
Hidalgo Guti xe9 rrez A, Barriocanal Casado E, D xed az Casado M, Gonz xe1 lez Garc xed a P, Zenezini Chiozzi R, Acu xf1 a Castroviejo D, et al. β-RA Targets Mitochondrial Metabolism and Adipogenesis, Leading to Therapeutic Benefits against CoQ Deficiency and Age-Related Overweight. Biomedicines. 2021;9: pubmed publisher
Angueira A, Sakers A, Holman C, Cheng L, Arbocco M, Shamsi F, et al. Defining the lineage of thermogenic perivascular adipose tissue. Nat Metab. 2021;3:469-484 pubmed publisher
Shook B, Wasko R, Mano O, Rutenberg Schoenberg M, Rudolph M, Zirak B, et al. Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair. Cell Stem Cell. 2020;26:880-895.e6 pubmed publisher
Pablos A, Ceca D, Jorda A, Rivera P, Colmena C, Elvira L, et al. Protective Effects of Foam Rolling against Inflammation and Notexin Induced Muscle Damage in Rats. Int J Med Sci. 2020;17:71-81 pubmed publisher
Borah A, Singh A, Yasmin R, Doley R, Mattaparthi V, Saha S. 1α, 25-dihydroxy Vitamin D3 containing fractions of Catharanthus roseus leaf aqueous extract inhibit preadipocyte differentiation and induce lipolysis in 3T3-L1 cells. BMC Complement Altern Med. 2019;19:338 pubmed publisher
Singh A, Borah A, Deka K, Gogoi A, Verma K, Barah P, et al. Arginylation regulates adipogenesis by regulating expression of PPARγ at transcript and protein level. Biochim Biophys Acta Mol Cell Biol Lipids. 2019;1864:596-607 pubmed publisher
Yang Y, Qu R, Fan T, Zhu X, Feng Y, Yang Y, et al. Cross-talk between microtubules and the linker of nucleoskeleton complex plays a critical role in the adipogenesis of human adipose-derived stem cells. Stem Cell Res Ther. 2018;9:125 pubmed publisher
product information
Product Type :
Antibody
Product Name :
PPAR gamma Monoclonal Antibody (K.242.9)
Catalog # :
MA5-14889
Quantity :
100 uL
Price :
US 464.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:400-1:1,600, Western Blot: 1:1,000
Species :
Human, Mouse
Clone :
K.242.9
Isotype :
IgG
Storage :
-20 C
Description :
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
Immunogen :
Synthetic peptide corresponding to residues surrounding Asp69 of human PPAR-gamma
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:400-1:1,600, Western Blot: 1:1,000
Aliases :
CIMT1; GLM1; HUMPPARG; NR1C3; nuclear hormone receptor; nuclear hormone receptor; PPARG; Nuclear receptor subfamily 1 group C member 3; nuclear receptor transcription factor; OTTHUMP00000185032; OTTHUMP00000185036; peroxisome proliferative activated receptor, gamma; peroxisome proliferative activated receptor, gamma-2; peroxisome proliferator; peroxisome proliferator activated receptor; peroxisome proliferator activated receptor gamma; peroxisome proliferator activated receptor gamma 1; peroxisome proliferator activated receptor gamma 2; peroxisome proliferator activated receptor gamma 4; peroxisome proliferator activated receptor gamma-1; peroxisome proliferator activated receptor gamma-2; peroxisome proliferator activatived receptor gamma; peroxisome proliferator activator receptor, gamma; peroxisome proliferator-activated nuclear receptor gamma variant 1; peroxisome proliferator-activated receptor; peroxisome proliferator-activated receptor gamma; peroxisome proliferator-activated receptor gamma 1; peroxisome proliferator-activated receptor gamma 1a; peroxisome proliferator-activated receptor gamma 1-a; peroxisome proliferator-activated receptor gamma 1b; peroxisome proliferator-activated receptor gamma 1-b; peroxisome proliferator-activated receptor gamma 1c; peroxisome proliferator-activated receptor gamma 1d; peroxisome proliferator-activated receptor gamma 2; peroxisome proliferator-activated receptor-gamma; peroxisome proliferator-activated receptor-gamma 2; peroxisome proliferator-cctivated receptor gamma 1; PPAR gamma; PPAR gamma 1; PPAR gamma 3; Pparg; PPARG1; PPARG2; PPARgamma; PPAR-gamma; PPARgamma2; PPAR-gamma2; PPARy; proliferator activated gamma; transcription factor
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA