GPX1 Monoclonal Antibody (K.163.2) | Invitrogen MA5-14868 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GPX1 Monoclonal Antibody (K.163.2)

catalog :

MA5-14868

quantity :

100 uL

price :

US 414.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

K.163.2

reactivity :

human

application :

western blot

citations: 20

Reference
Wong F, Selten M, Rosés Novella C, Sreenivasan V, Pallas Bazarra N, Serafeimidou Pouliou E, et al. Serotonergic regulation of bipolar cell survival in the developing cerebral cortex. Cell Rep. 2022;40:111037 pubmed publisher
Tsortouktzidis D, Tröscher A, Schulz H, Opitz T, Schoch S, Becker A, et al. A Versatile Clustered Regularly Interspaced Palindromic Repeats Toolbox to Study Neurological CaV3.2 Channelopathies by Promoter-Mediated Transcription Control. Front Mol Neurosci. 2021;14:667143 pubmed publisher
Desai V, Chouaref J, Wu H, Pastor W, Kan R, Oey H, et al. The role of MORC3 in silencing transposable elements in mouse embryonic stem cells. Epigenetics Chromatin. 2021;14:49 pubmed publisher
Wu J, Chen Z, Wickström S, Gao J, He X, Jing X, et al. Interleukin-33 is a Novel Immunosuppressor that Protects Cancer Cells from TIL Killing by a Macrophage-Mediated Shedding Mechanism. Adv Sci (Weinh). 2021;8:e2101029 pubmed publisher
Voss G, Edsjö A, Bjartell A, Ceder Y. Quantification of microRNA editing using two-tailed RT-qPCR for improved biomarker discovery. RNA. 2021;27:1412-1424 pubmed publisher
Holzner S, Bromberger S, Wenzina J, Neumüller K, Holper T, Petzelbauer P, et al. Phosphorylated cingulin localises GEF-H1 at tight junctions to protect vascular barriers in blood endothelial cells. J Cell Sci. 2021;: pubmed publisher
Zielke S, Kardo S, Zein L, Mari M, Covarrubias Pinto A, Kinzler M, et al. ATF4 links ER stress with reticulophagy in glioblastoma cells. Autophagy. 2020;:1-17 pubmed publisher
Wyckelsma V, Venckunas T, Brazaitis M, Gastaldello S, Snieckus A, Eimantas N, et al. Vitamin C and E Treatment Blunts Sprint Interval Training-Induced Changes in Inflammatory Mediator-, Calcium-, and Mitochondria-Related Signaling in Recreationally Active Elderly Humans. Antioxidants (Basel). 2020;9: pubmed publisher
Cheng A, Tse K, Chow H, Gan Y, Song X, Ma F, et al. ATM loss disrupts the autophagy-lysosomal pathway. Autophagy. 2020;:1-13 pubmed publisher
Gambelunghe A, Giovagnoli S, Di Michele A, Boncompagni S, Dell Omo M, Leopold K, et al. Redox-Sensitive Glyoxalase 1 Up-Regulation Is Crucial for Protecting Human Lung Cells from Gold Nanoparticles Toxicity. Antioxidants (Basel). 2020;9: pubmed publisher
Lin T, Chan H, Chen S, Sarvagalla S, Chen P, Coumar M, et al. BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells. Autophagy. 2019;:1-18 pubmed publisher
Khoshchehreh R, Totonchi M, Carlos Ramírez J, Torres R, Baharvand H, Aicher A, et al. Epigenetic reprogramming of primary pancreatic cancer cells counteracts their in vivo tumourigenicity. Oncogene. 2019;38:6226-6239 pubmed publisher
Li H, Petersen S, García Mariscal A, Brakebusch C. Negative Regulation of p53-Induced Senescence by N-WASP Is Crucial for DMBA/TPA-Induced Skin Tumor Formation. Cancer Res. 2019;79:2167-2181 pubmed publisher
Geissler S, Textor M, Stumpp S, Seitz S, Lekaj A, Brunk S, et al. Loss of murine Gfi1 causes neutropenia and induces osteoporosis depending on the pathogen load and systemic inflammation. PLoS ONE. 2018;13:e0198510 pubmed publisher
Li H, Yao Q, Mariscal A, Wu X, Hulse J, Pedersen E, et al. Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation. Nat Commun. 2018;9:1420 pubmed publisher
Valero Jiménez A, Zuniga J, Cisneros J, Becerril C, Salgado A, Checa M, et al. Transmembrane protease, serine 4 (TMPRSS4) is upregulated in IPF lungs and increases the fibrotic response in bleomycin-induced lung injury. PLoS ONE. 2018;13:e0192963 pubmed publisher
Fransen M, Benonisson H, van Maren W, Sow H, Breukel C, Linssen M, et al. A Restricted Role for FcγR in the Regulation of Adaptive Immunity. J Immunol. 2018;200:2615-2626 pubmed publisher
Oskarsson M, Hermansson E, Wang Y, Welsh N, Presto J, Johansson J, et al. BRICHOS domain of Bri2 inhibits islet amyloid polypeptide (IAPP) fibril formation and toxicity in human beta cells. Proc Natl Acad Sci U S A. 2018;115:E2752-E2761 pubmed publisher
Li B, Li Z, Wang P, Huang Q, Xu L, He R, et al. Mammalian target of rapamycin complex 1 signalling is essential for germinal centre reaction. Immunology. 2017;152:276-286 pubmed publisher
Taghiyar L, Hesaraki M, Sayahpour F, Satarian L, Hosseini S, Aghdami N, et al. Msh homeobox 1 (Msx1)- and Msx2-overexpressing bone marrow-derived mesenchymal stem cells resemble blastema cells and enhance regeneration in mice. J Biol Chem. 2017;292:10520-10533 pubmed publisher

product information

Product Type :

Antibody

Product Name :

GPX1 Monoclonal Antibody (K.163.2)

Catalog # :

MA5-14868

Quantity :

100 uL

Price :

US 414.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Western Blot: 1:1,000

Species :

Human

Clone :

K.163.2

Isotype :

IgG

Storage :

-20 C

Description :

Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.

Immunogen :

Synthetic peptide corresponding to the sequence of human GPX1

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

AI195024; AL033363; Cellular glutathione peroxidase; CGPx; cytosolic glutathione peroxidase; glutathione peroxidase; glutathione peroxidase 1; Gpx; Gpx1; GPx-1; GPXD; GSHPx; GSHPX1; GSHPx-1; HGNC:4553; MGC14399; MGC88245; OTTHUMP00000210766; Selenium-dependent glutathione peroxidase 1