AP2 alpha Monoclonal Antibody (R.387.0) | Invitrogen MA5-14856 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

AP2 alpha Monoclonal Antibody (R.387.0)

catalog :

MA5-14856

quantity :

100 uL

price :

US 474.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

clone name :

R.387.0

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

citations: 3

Reference
Kołat D, Kałuzińska Ż, Bednarek A, Płuciennik E. WWOX Loses the Ability to Regulate Oncogenic AP-2γ and Synergizes with Tumor Suppressor AP-2α in High-Grade Bladder Cancer. Cancers (Basel). 2021;13: pubmed publisher
Kołat D, Kałuzińska Ż, Płuciennik E. Fragile Gene WWOX Guides TFAP2A/TFAP2C-Dependent Actions Against Tumor Progression in Grade II Bladder Cancer. Front Oncol. 2021;11:621060 pubmed publisher
Kałuzińska Ż, Kołat D, Kosla K, Orzechowska M, Bednarek A, Płuciennik E. In vitro and in silico assessment of the effect of WWOX expression on invasiveness pathways associated with AP-2 transcription factors in bladder cancer. BMC Urol. 2021;21:36 pubmed publisher

product information

Product Type :

Antibody

Product Name :

AP2 alpha Monoclonal Antibody (R.387.0)

Catalog # :

MA5-14856

Quantity :

100 uL

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

Immunocytochemistry: 1:100, Western Blot: 1:1,000

Species :

Human, Mouse, Non-human primate, Rat

Clone :

R.387.0

Isotype :

IgG

Storage :

-20 C

Description :

TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.

Immunogen :

Synthetic peptide corresponding to human AP-2a

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Western Blot: 1:1,000

Aliases :

activating enhancer-binding protein 2 alpha; activating enhancer-binding protein 2-alpha; Activator protein 2; activator protein 2 alpha variant 4; activator protein 2 alpha variant 6; activator protein 2 alpha variant 7; AP2; AP-2; Ap-2 (a); AP-2 transcription factor; AP2alpha; AP-2alpha; AP2-alpha; Ap2tf; BOFS; ERF-1; FLJ51761; OTTHUMP00000214240; OTTHUMP00000214243; Tcfap2a; TFAP2; TFAP2A; transcription factor AP2; transcription factor AP-2 alpha; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); transcription factor AP-2, alpha; transcription factor AP-2-alpha; transcription factor AP-2-alpha-like; transcription factor; AP-2