HK2 Monoclonal Antibody (H.738.7) | Invitrogen MA5-14849 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HK2 Monoclonal Antibody (H.738.7)

catalog :

MA5-14849

quantity :

100 µL

price :

US 496

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

H.738.7

reactivity :

human, mouse, rat

application :

western blot

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1	Kudryavtseva A, Fedorova M, Zhavoronkov A, Moskalev A, Zasedatelev A, Dmitriev A, et al. Effect of lentivirus-mediated shRNA inactivation of HK1, HK2, and HK3 genes in colorectal cancer and melanoma cells. BMC Genet. 2016;17:156 pubmed publisher
	Bae S, Berlth F, Jeong K, Suh Y, Kong S, Lee H, et al. Establishment of a [18F]-FDG-PET/MRI Imaging Protocol for Gastric Cancer PDX as a Preclinical Research Tool. J Gastric Cancer. 2020;20:60-71 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HK2 Monoclonal Antibody (H.738.7)

Catalog # :

MA5-14849

Quantity :

100 µL

Price :

US 496

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

Western Blot: 1:1,000

Species :

Human, Mouse, Non-human primate, Rat

Clone :

H.738.7

Isotype :

IgG

Storage :

-20°C

Description :

In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Immunogen :

Synthetic peptide corresponding to residues surrounding Ser340 of sequence of human hexokinase II.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

AI642394; DKFZp686M1669; Hexokinase; hexokinase 2; hexokinase II; hexokinase type II; Hexokinase-2; hexokinase-2 muscle; hexokinase-2, muscle; Hexokinase-B; HK II; Hk2; HKII; HXK2; muscle form hexokinase; OTTHUMP00000202738