PSIP1 Monoclonal Antibody (E.493.5) | Invitrogen MA5-14821 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PSIP1 Monoclonal Antibody (E.493.5)

catalog :

MA5-14821

quantity :

100 uL

price :

US 434.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

E.493.5

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 1

Reference
Leung W, Teater M, Durmaz C, Meydan C, Chivu A, Chadburn A, et al. SETD2 Haploinsufficiency Enhances Germinal Center-Associated AICDA Somatic Hypermutation to Drive B-cell Lymphomagenesis. Cancer Discov. 2022;12:1782-1803 pubmed publisher

product information

Product Type :

Antibody

Product Name :

PSIP1 Monoclonal Antibody (E.493.5)

Catalog # :

MA5-14821

Quantity :

100 uL

Price :

US 434.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ChIP Assay: 10 uL/10^6 cells, Flow Cytometry: 1:100, Immunocytochemistry: 1:250-1:400, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:1,000

Species :

Human, Mouse, Rat

Clone :

E.493.5

Isotype :

IgG

Storage :

-20 C

Description :

Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.

Immunogen :

Synthetic peptide corresponding to amino acids surrounding Lys461 of human LEDGF

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 10 uL/10^6 cells, Flow Cytometry: 1:100, Immunocytochemistry: 1:250-1:400, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:1,000

Aliases :

AA408851; AU015605; CLL-associated antigen KW-7; dense fine speckles 70; dense fine speckles 70 kDa protein; DFS 70; DFS70; LEDGF; Ledgfa; Ledgfb; Lens epithelium-derived growth factor; mLEDGF; p52; p75; PAIP; PC4 and SFRS1 interacting protein 1; PC4 and SFRS1 interacting protein 2; PC4 and SFRS1-interacting protein; PSIP1; Psip2; SBP75; supercoiled DNA binding protein 75; transcriptional coactivator p52/p75; Transcriptional coactivator p75/p52