Phospho-Bim (Ser69) Monoclonal Antibody (K.724.4) | Invitrogen MA5-14814 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-Bim (Ser69) Monoclonal Antibody (K.724.4)

catalog :

MA5-14814

quantity :

100 uL

price :

US 474.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

K.724.4

reactivity :

human, mouse

application :

western blot, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

Phospho-Bim (Ser69) Monoclonal Antibody (K.724.4)

Catalog # :

MA5-14814

Quantity :

100 uL

Price :

US 474.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunoprecipitation: 1:50, Western Blot: 1:1,000

Species :

Human, Mouse

Clone :

K.724.4

Isotype :

IgG

Storage :

-20 C

Description :

BIM belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

Immunogen :

Synthetic phosphopeptide corresponding to residues surrounding pSer69 of human Bim protein

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: 1:50, Western Blot: 1:1,000

Aliases :

1500006F24Rik; BAM; Bcl2 interacting mediator of cell death; bcl-2 interacting mediator of cell death; bcl-2 interacting protein Bim; BCL2 like 11; Bcl-2 like 11; Bcl-2 related apoptotic gene product BimL; bcl2-interacting mediator of cell death; BCL2L11; Bcl2-L-11; BCL2-like 11 (apoptosis facilitator); bcl-2-like protein 11; bcl-2-like protein 11-like; bcl-2-related ovarian death agonist; bcl-2-related ovarian death protein; BIM; Bim EL; Bim-A; BIM-alpha6; BIM-beta6; BIM-beta7; BIMEL; BimEL protein; BimL; BOD; OTTHUMP00000197013; OTTHUMP00000204247; Unknown (protein for MGC:134444)