KSHV ORF62 Monoclonal Antibody (5B7B6) | Invitrogen MA5-14770 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KSHV ORF62 Monoclonal Antibody (5B7B6)

catalog :

MA5-14770

quantity :

100 uL

price :

US 491.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5B7B6

reactivity :

Human gammaherpesvirus 8

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

citations: 1

Reference
Walker L, Hussein H, Akula S. Subcellular fractionation method to study endosomal trafficking of Kaposi's sarcoma-associated herpesvirus. Cell Biosci. 2016;6:1 pubmed publisher

product information

Product Type :

Antibody

Product Name :

KSHV ORF62 Monoclonal Antibody (5B7B6)

Catalog # :

MA5-14770

Quantity :

100 uL

Price :

US 491.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Virus

Applications :

ELISA: 1:10,000, Immunocytochemistry: Assay-dependent, Immunohistochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000

Species :

Virus

Clone :

5B7B6

Isotype :

IgM

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. At least five major proteins are likely to be involved in the assembly of the HHV-8 capsid, including a protease (encoded by ORF17), the major capsid protein (encoded by ORF25), and three other smaller capsid proteins (encoded by ORF62, ORF26, and ORF65). Previous structural studies have shown that the HSV-1 triplex is a monomer of VP19c and a dimer of VP23 and that the HCMV triplex is similarly composed of a monomer and a dimer. By analogy, the KSHV triplexes are likely also composed of a monomer of the ORF62 protein and a dimer of the ORF26 protein, which are the respective homologs of VP19c and VP23.

Immunogen :

Purified recombinant fragment of human KSHV ORF62 expressed in E. Coli.

Format :

Liquid

Applications w/Dilutions :

ELISA: 1:10,000, Immunocytochemistry: Assay-dependent, Immunohistochemistry: 1:200-1:1,000, Western Blot: 1:500-1:2,000

Aliases :

Kaposi's Sarcoma Virus; Kaposi's sarcoma-associated herpesvirus