This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
GRP94 Monoclonal Antibody (9G10.F8.2)
catalog :
MA5-14592
quantity :
500 uL
price :
US 474.00
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
9G10.F8.2

The same clone is also sold as:
reactivity :
guinea pig, Chinese hamsters, human, mouse, rat, dogs, chicken, bovine, pigs , domestic sheep, Xenopus laevis, domestic rabbit, domestic horse
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 4
Reference
Hayoun D, Kapp T, Edri Brami M, Ventura T, Cohen M, Avidan A, et al. HSP60 is transported through the secretory pathway of 3-MCA-induced fibrosarcoma tumour cells and undergoes N-glycosylation. FEBS J. 2012;279:2083-95 pubmed publisher
Chiu C, Lin C, Lee L, Chen Y, Lu Y, Wang H, et al. Molecular chaperones as a common set of proteins that regulate the invasion phenotype of head and neck cancer. Clin Cancer Res. 2011;17:4629-41 pubmed publisher
Tang Y, Li H, Hamel J. Significances of pH and temperature on the production of heat-shock protein glycoprotein 96 by MethA tumor cell suspension culture in stirred-tank bioreactors. Bioprocess Biosyst Eng. 2009;32:267-76 pubmed publisher
Chen Y, Ashok B, Liu X, Garikapaty V, Mittelman A, Tiwari R. Induction of heat shock protein gp96 by immune cytokines. Cell Stress Chaperones. 2003;8:242-8 pubmed
product information
Product Type :
Antibody
Product Name :
GRP94 Monoclonal Antibody (9G10.F8.2)
Catalog # :
MA5-14592
Quantity :
500 uL
Price :
US 474.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Rat
Reactivity :
Bovine, Canine, Chicken, Equine, Guinea Pig, Hamster, Human, Mouse, Non-human primate, Ovine, Porcine, Rabbit, Rat, Xenopus laevis
Applications :
Immunohistochemistry (Paraffin): 1-2 ug/mL, Immunoprecipitation: 2 ug/mL, Western Blot: 1-2 ug/mL
Species :
Bovine, Canine, Chicken, Equine, Guinea Pig, Hamster, Human, Mouse, Non-human primate, Ovine, Porcine, Rabbit, Rat, Xenopus laevis
Clone :
9G10.F8.2
Isotype :
IgG2a
Storage :
4 C
Description :
GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells.
Immunogen :
Purified glucose regulated protein 94 (grp94) from chicken oviducts
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1-2 ug/mL, Immunoprecipitation: 2 ug/mL, Western Blot: 1-2 ug/mL
Aliases :
108K heat shock protein; 108K HSP; 94 kDa glucose-regulated protein; 94 kDa glucose-regulated protein {ECO:0000250; 98 kDa protein kinase; ecgp; endoplasmic reticulum resident protein 99; Endoplasmin; endoplasmin {ECO:0000250; endoplasmin-like protein; endothelial cell (HBMEC) glycoprotein; epididymis luminal protein 35; epididymis secretory sperm binding protein Li 125m; ERp99; glucose-regulated protein; glucose-regulated protein GRP94; glucose-regulated protein GRP94 precursor; GP96; gp96 homolog; gp96/GRP94; GRP94; GRP-94; heat shock 108 kDa protein; heat shock protein 108; heat shock protein 108.; heat shock protein 90 beta family member 1; heat shock protein 90 kDa beta member 1; heat shock protein 90 kDa beta member 1 {ECO:0000250; heat shock protein 90, beta (Grp94), member 1; heat shock protein 90, beta, member 1; heat shock protein 90kDa beta (Grp94), member 1; heat shock protein 90kDa beta family member 1; heat shock protein 90kDa beta family member 1 L homeolog; heat shock protein 90kDa beta, member 1; heat shock protein gp96; HEL35; HEL-S-125m; HSP 108; hsp108; HSP90 beta; hsp90b1; hsp90b1 {ECO:0000250; hsp90b1.L; Polymorphic tumor rejection antigen 1; PPK 98; Ppk 98; a protein kinase; ppk98; stress-inducible tumor rejection antigen gp96; TA-3; Targ2; tra1; Tra-1; transferrin-binding protein; transforming growth factor alpha regulated gene 2; tumor rejection antigen; tumor rejection antigen (gp96) 1; tumor rejection antigen 1; Tumor rejection antigen gp96; UniProtKB:P08113}; XELAEV_18017384mg
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA