CD23 Monoclonal Antibody (SP23) | Invitrogen MA5-14572 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD23 Monoclonal Antibody (SP23)

catalog :

MA5-14572

quantity :

500 uL

price :

US 542.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

SP23

reactivity :

human, mouse

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 2c	Agaimy A, Michal M, Hadravsky L, Michal M. Follicular dendritic cell sarcoma: clinicopathologic study of 15 cases with emphasis on novel expression of MDM2, somatostatin receptor 2A, and PD-L1. Ann Diagn Pathol. 2016;23:21-8 pubmed publisher
immunohistochemistry; human; 1:25	Kap M, Lam K, Ewing Graham P, Riegman P. A reference image-based method for optimization of clinical immunohistochemistry. Histopathology. 2015;67:193-205 pubmed publisher
immunohistochemistry; human; 1:100	Cubas R, Mudd J, Savoye A, Perreau M, van Grevenynghe J, Metcalf T, et al. Inadequate T follicular cell help impairs B cell immunity during HIV infection. Nat Med. 2013;19:494-9 pubmed publisher
immunohistochemistry - paraffin section; human; 1:25	Kap M, Smedts F, Oosterhuis W, Winther R, Christensen N, Reischauer B, et al. Histological assessment of PAXgene tissue fixation and stabilization reagents. PLoS ONE. 2011;6:e27704 pubmed publisher
immunohistochemistry; human	Piconese S, Costanza M, Tripodo C, Sangaletti S, Musio S, Pittoni P, et al. The matricellular protein SPARC supports follicular dendritic cell networking toward Th17 responses. J Autoimmun. 2011;37:300-10 pubmed publisher
immunohistochemistry; human	Kwon M, Jung S, Kim Y, Ha K. Simultaneous activity assay of two transglutaminase isozymes, blood coagulation factor XIII and transglutaminase 2, by use of fibrinogen arrays. Anal Chem. 2011;83:8718-24 pubmed publisher
immunohistochemistry; human; 1:400	Gualco G, Klumb C, Barber G, Weiss L, Bacchi C. Pediatric lymphomas in Brazil. Clinics (Sao Paulo). 2010;65:1267-77 pubmed
immunohistochemistry; human	Gladkikh A, Potashnikova D, Korneva E, Khudoleeva O, Vorobjev I. Cyclin D1 expression in B-cell lymphomas. Exp Hematol. 2010;38:1047-57 pubmed publisher
immunohistochemistry; human; 1:200	Bhagavathi S, Micale M, Douglas Nikitin V, Ballouz S, Neumann K, Blenc A. Composite biclonal marginal zone lymphoma of lung and chronic lymphocytic leukemia: pathologic, phenotypic, cytogenetic, and molecular study. Int J Surg Pathol. 2011;19:377-81 pubmed publisher
immunohistochemistry; human; 1:400	Queiroga E, Gualco G, Weiss L, Dittmer D, Araujo I, Klumb C, et al. Burkitt lymphoma in Brazil is characterized by geographically distinct clinicopathologic features. Am J Clin Pathol. 2008;130:946-56 pubmed publisher
immunohistochemistry; human; 1:100	Krokowski M, Merz H, Thorns C, Bernd H, Schade U, Le Tourneau A, et al. Sarcoma of follicular dendritic cells with features of sinus lining cells--a new subtype of reticulum cell sarcoma?. Virchows Arch. 2008;452:565-70 pubmed publisher
	Shang T, Jiang T, Lu T, Wang H, Cui X, Pan Y, et al. Tertiary lymphoid structures predict the prognosis and immunotherapy response of cholangiocarcinoma. Front Immunol. 2023;14:1166497 pubmed publisher
	Chaurio R, Anadon C, Lee Costich T, Payne K, Biswas S, Harro C, et al. TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures. Immunity. 2022;55:115-128.e9 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD23 Monoclonal Antibody (SP23)

Catalog # :

MA5-14572

Quantity :

500 uL

Price :

US 542.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 1:2, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:10-1:100

Species :

Human, Mouse

Clone :

SP23

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.

Immunogen :

Recombinant fragment within Human CD23 aa 1-250. The exact sequence is proprietary.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:2, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:10-1:100

Aliases :

BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; Fce2; fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; lymphocyte IgE receptor

more info or order :

Invitrogen product webpage