| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; fig 1a
| Jindal S, Pennock N, Klug A, Narasimhan J, Calhoun A, Roberts M, et al. S-nitrosylated and non-nitrosylated COX2 have differential expression and distinct subcellular localization in normal and breast cancer tissue. NPJ Breast Cancer. 2020;6:62 pubmed publisher |
- western blot; rat; 1:2000; loading ...; fig 8
| Singh M, Kasna S, Roy S, Aldosary S, Saeedan A, Ansari M, et al. Repurposing mechanistic insight of PDE-5 inhibitor in cancer chemoprevention through mitochondrial-oxidative stress intervention and blockade of DuCLOX signalling. BMC Cancer. 2019;19:996 pubmed publisher |
- western blot; mouse; 1:2000; loading ...; fig 4f
| Yang X, Huo F, Liu B, Liu J, Chen T, Li J, et al. Crocin Inhibits Oxidative Stress and Pro-inflammatory Response of Microglial Cells Associated with Diabetic Retinopathy Through the Activation of PI3K/Akt Signaling Pathway. J Mol Neurosci. 2017;61:581-589 pubmed publisher |
- immunohistochemistry - paraffin section; dogs; 1:1500; loading ...; fig 1c
| Yabuki A, Miyazaki A, Ichii O, Kohyama M, Sawa M, Yamato O. Low expression of cyclooxygenase-2 in chronic kidney disease in young dogs. Res Vet Sci. 2016;109:71-73 pubmed publisher |
- immunohistochemistry; dogs; loading ...; fig 2b
| Carvalho S, Stoll A, Priestnall S, Suárez Bonnet A, Rassnick K, Lynch S, et al. Retrospective evaluation of COX-2 expression, histological and clinical factors as prognostic indicators in dogs with renal cell carcinomas undergoing nephrectomy. Vet Comp Oncol. 2017;15:1280-1294 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1
| Hafez N, Tahoun N. Expression of cyclooxygenase 2 and vascular endothelial growth factor in gastric carcinoma: Relationship with clinicopathological parameters. J Egypt Natl Canc Inst. 2016;28:149-56 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:50
| Remo A, Simeone I, Pancione M, Parcesepe P, Finetti P, Cerulo L, et al. Systems biology analysis reveals NFAT5 as a novel biomarker and master regulator of inflammatory breast cancer. J Transl Med. 2015;13:138 pubmed publisher |
- immunohistochemistry - paraffin section; domestic goat; 1:20
| RodrÃguez F, Poveda J, Jaber J, Orós J, RodrÃguez J. Expression of cyclooxygenase-2 in the mammary gland tissue of goats affected with caprine contagious agalactia. Vet J. 2015;204:125-7 pubmed publisher |
- immunohistochemistry - paraffin section; cat; 1:75
| Saraiva A, Payan Carreira R, Gärtner F, Santana I, Rêma A, Lourenço L, et al. Immunohistochemical expression of cyclooxygenase-2 (COX-2) in feline endometrial adenocarcinoma and in normal and hyperplastic endometria. Reprod Domest Anim. 2015;50:333-40 pubmed publisher |
- immunohistochemistry; human
| Urban J, Kuźbicki Å, Szatkowski G, Stanek Widera A, Lange D, Chwirot B. Stromal, rather than epithelial cyclooxygenase-2 (COX-2) expression is associated with overall survival of breast cancer patients. BMC Cancer. 2014;14:732 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:50; fig 5
| Stodden G, Lindberg M, King M, Paquet M, MacLean J, Mann J, et al. Loss of Cdh1 and Trp53 in the uterus induces chronic inflammation with modification of tumor microenvironment. Oncogene. 2015;34:2471-82 pubmed publisher |
- immunohistochemistry; rat; 1:100; fig 1, 2, 3
| Basak K, Doguc D, Aylak F, Karadayi N, Gultekin F. Effects of maternally exposed food coloring additives on laryngeal histology in rats. J Environ Pathol Toxicol Oncol. 2014;33:123-30 pubmed |
- immunohistochemistry; human
| Pomianowska E, Sandnes D, Grzyb K, Schjølberg A, Aasrum M, Tveteraas I, et al. Inhibitory effects of prostaglandin E2 on collagen synthesis and cell proliferation in human stellate cells from pancreatic head adenocarcinoma. BMC Cancer. 2014;14:413 pubmed publisher |
- immunohistochemistry; human; 1:100
| Lobo Prabhu K, Vu L, Chan S, Phang T, Gown A, Jones S, et al. Predictive utility of cyclo-oxygenase-2 expression by colon and rectal cancer. Am J Surg. 2014;207:712-6 pubmed publisher |
- immunohistochemistry; human; 1:50
| Linhares P, Martinho O, Carvalho B, Castro L, Lopes J, Vaz R, et al. Analysis of a synchronous gliosarcoma and meningioma with long survival: A case report and review of the literature. Surg Neurol Int. 2013;4:151 pubmed publisher |
- immunohistochemistry; human; 1:100
| Matthaei M, Hu J, Meng H, Lackner E, Eberhart C, Qian J, et al. Endothelial cell whole genome expression analysis in a mouse model of early-onset Fuchs' endothelial corneal dystrophy. Invest Ophthalmol Vis Sci. 2013;54:1931-40 pubmed publisher |
- immunohistochemistry; human; 1:100
| Mitra A, Castelao J, Hawes D, Tsao Wei D, Jiang X, Shi S, et al. Combination of molecular alterations and smoking intensity predicts bladder cancer outcome: a report from the Los Angeles Cancer Surveillance Program. Cancer. 2013;119:756-65 pubmed publisher |
- immunohistochemistry; human
| Erkan G, Gonul I, Kandilci U, Dursun A. Assessment of COX-2 expression presence and severity by immunohistochemical method in patients with chronic active gastritis and intestinal metaplasia. Turk J Gastroenterol. 2012;23:478-84 pubmed |
- immunohistochemistry; human; fig s1
| Czachorowski M, Amaral A, Montes Moreno S, Lloreta J, Carrato A, Tardon A, et al. Cyclooxygenase-2 expression in bladder cancer and patient prognosis: results from a large clinical cohort and meta-analysis. PLoS ONE. 2012;7:e45025 pubmed publisher |
- immunohistochemistry - paraffin section; rat; fig 1
| Haligur M, Topsakal S, Ozmen O. Early degenerative effects of diabetes mellitus on pancreas, liver, and kidney in rats: an immunohistochemical study. Exp Diabetes Res. 2012;2012:120645 pubmed publisher |
- immunohistochemistry - paraffin section; pigs ; fig 1
| Oláh O, Nemeth I, Toth Szuki V, Bari F, Domoki F. Regional Differences in the Neuronal Expression of Cyclooxygenase-2 (COX-2) in the Newborn Pig Brain. Acta Histochem Cytochem. 2012;45:187-92 pubmed publisher |
- immunohistochemistry; bovine; 1:20
| Herzog K, Str ve K, Kastelic J, Piechotta M, Ulbrich S, Pfarrer C, et al. Escherichia coli lipopolysaccharide administration transiently suppresses luteal structure and function in diestrous cows. Reproduction. 2012;144:467-76 pubmed publisher |
- immunohistochemistry; mouse
| Hill R, Li Y, Tran L, Dry S, Calvopina J, Garcia A, et al. Cell intrinsic role of COX-2 in pancreatic cancer development. Mol Cancer Ther. 2012;11:2127-37 pubmed publisher |
- immunohistochemistry; dogs; 1:50
| Vascellari M, Giantin M, Capello K, Carminato A, Morello E, Vercelli A, et al. Expression of Ki67, BCL-2, and COX-2 in canine cutaneous mast cell tumors: association with grading and prognosis. Vet Pathol. 2013;50:110-21 pubmed publisher |
- immunohistochemistry; human; 1:50
| Jiang J, Jin M, Suo J, Wang Y, He L, Cao X. Evaluation of malignancy using Ki-67, p53, EGFR and COX-2 expressions in gastrointestinal stromal tumors. World J Gastroenterol. 2012;18:2569-75 pubmed publisher |
- immunohistochemistry; human; 1:200
| Almeida P, Ferreira F, Santos C, Rocha Filho F, Feitosa R, Falcão E, et al. Immunoexpression of cyclooxygenase-2 in primary gastric carcinomas and lymph node metastases. World J Gastroenterol. 2012;18:778-84 pubmed publisher |
| Barnes C, Prox D, Christison Lagay E, Le H, Short S, Cassiola F, et al. Inhibition of neuroblastoma cell proliferation with omega-3 fatty acids and treatment of a murine model of human neuroblastoma using a diet enriched with omega-3 fatty acids in combination with sunitinib. Pediatr Res. 2012;71:168-78 pubmed publisher |
- immunohistochemistry; human; 1:50
| Lindquist D, Ährlund Richter A, Tarján M, Tot T, Dalianis T. Intense CD44 expression is a negative prognostic factor in tonsillar and base of tongue cancer. Anticancer Res. 2012;32:153-61 pubmed |
- immunohistochemistry; dogs; 1:50
| Prada J, Queiroga F, Gregório H, Pires I. Evaluation of cyclooxygenase-2 expression in canine mast cell tumours. J Comp Pathol. 2012;147:31-6 pubmed publisher |
- immunohistochemistry; domestic rabbit; 1:1000
| Fouad A, Jresat I. Therapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats. Eur J Pharmacol. 2011;670:216-23 pubmed publisher |
- immunohistochemistry; human
| Shatzel J, Wooten K, Ankola A, Cheney R, Morrison C, Skitzki J. Inflammatory myofibroblastic tumor of the mesentery: a clinical dilemma. Int J Clin Oncol. 2012;17:380-4 pubmed publisher |
- immunohistochemistry; human
| Holmes M, Chen W, Schnitt S, Collins L, Colditz G, Hankinson S, et al. COX-2 expression predicts worse breast cancer prognosis and does not modify the association with aspirin. Breast Cancer Res Treat. 2011;130:657-62 pubmed publisher |
- immunohistochemistry; human; 1:100
| Çiriş I, Bozkurt K, Baspinar S, Kapucuoğlu F. Immunohistochemical COX-2 overexpression correlates with HER-2/neu overexpression in invasive breast carcinomas: a pilot study. Pathol Res Pract. 2011;207:182-7 pubmed publisher |
- immunohistochemistry; human; 1:100
| Cortés Ramírez D, Rodriguez Tojo M, Gainza Cirauqui M, Martinez Conde R, Aguirre Urizar J. Overexpression of cyclooxygenase-2 as a biomarker in different subtypes of the oral lichenoid disease. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;110:738-43 pubmed publisher |
- immunohistochemistry; mouse
| Fini L, Piazzi G, Ceccarelli C, Daoud Y, Belluzzi A, Munarini A, et al. Highly purified eicosapentaenoic acid as free fatty acids strongly suppresses polyps in Apc(Min/+) mice. Clin Cancer Res. 2010;16:5703-11 pubmed publisher |
- immunohistochemistry; rat; 1:400
| Lima Rodrigues M, Lamas N, Valle Fernandes A, Cruz A, Vieira A, Oliveira P, et al. The selective COX-2 inhibitor Etoricoxib reduces acute inflammatory markers in a model of neurogenic laryngitis but loses its efficacy with prolonged treatment. Inflamm Res. 2010;59:743-53 pubmed publisher |
- immunocytochemistry; human; 1:100
| Galamb O, Spisak S, Sipos F, Toth K, Solymosi N, Wichmann B, et al. Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor. Br J Cancer. 2010;102:765-73 pubmed publisher |
- immunohistochemistry; human
| Türköz H, Alkan I, Sişman S, Ozcan D. Cyclooxygenase-2 expression and connection with tumor recurrence and histopathologic parameters in gastrointestinal stromal tumors. APMIS. 2009;117:825-30 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:800; fig 1
| Daugaard S, Christensen L, Høgdall E. Markers aiding the diagnosis of chondroid tumors: an immunohistochemical study including osteonectin, bcl-2, cox-2, actin, calponin, D2-40 (podoplanin), mdm-2, CD117 (c-kit), and YKL-40. APMIS. 2009;117:518-25 pubmed publisher |
- immunohistochemistry; human; 1:100
| Suesskind D, Paulsen F, Buchgeister M, Spitzer B, Rohrbach J, Bartz Schmidt K, et al. Cyclo-oxygenase-2 expression in photon-radiated and non-radiated uveal melanomas. Acta Ophthalmol. 2010;88:582-7 pubmed publisher |
- immunohistochemistry; rat; 1:100
| Razga Z, Nyengaard J. The effect of angiotensin II on the number of macula densa cells through the AT1 receptor. Nephron Physiol. 2009;112:p37-43 pubmed publisher |
- immunohistochemistry; mouse; 1:1000
| Wilkey J, Buchberger G, Saucier K, Patel S, Eisenberg E, Nakagawa H, et al. Cyclin D1 overexpression increases susceptibility to 4-nitroquinoline-1-oxide-induced dysplasia and neoplasia in murine squamous oral epithelium. Mol Carcinog. 2009;48:853-61 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:75; tbl 2
| Gil da Costa R, Santos M, Amorim I, Lopes C, Pereira P, Faustino A. An immunohistochemical study of feline endometrial adenocarcinoma. J Comp Pathol. 2009;140:254-9 pubmed publisher |
- immunohistochemistry; human
| Jalili A, Pinc A, Pieczkowski F, Karlhofer F, Stingl G, Wagner S. Combination of an EGFR blocker and a COX-2 inhibitor for the treatment of advanced cutaneous squamous cell carcinoma. J Dtsch Dermatol Ges. 2008;6:1066-9 pubmed publisher |
- immunohistochemistry; human; 1:100
| Hasan S, Satake M, Dawson D, Funahashi H, Angst E, Go V, et al. Expression analysis of the prostaglandin E2 production pathway in human pancreatic cancers. Pancreas. 2008;37:121-7 pubmed publisher |
- immunohistochemistry; human
| Leung W, Wu K, Wong C, Cheng A, Ching A, Chan A, et al. Transgenic cyclooxygenase-2 expression and high salt enhanced susceptibility to chemical-induced gastric cancer development in mice. Carcinogenesis. 2008;29:1648-54 pubmed publisher |
- immunohistochemistry; human; 1:50
| Edelman M, Watson D, Wang X, Morrison C, Kratzke R, Jewell S, et al. Eicosanoid modulation in advanced lung cancer: cyclooxygenase-2 expression is a positive predictive factor for celecoxib + chemotherapy--Cancer and Leukemia Group B Trial 30203. J Clin Oncol. 2008;26:848-55 pubmed publisher |
- immunohistochemistry; rat; 1:400
| Lima Rodrigues M, Valle Fernandes A, Lamas N, Cruz A, Baltazar F, Milanezi F, et al. A new model of laryngitis: neuropeptide, cyclooxygenase, and cytokine profile. Laryngoscope. 2008;118:78-86 pubmed publisher |
- immunohistochemistry; human; 1:150
| Hammes L, Korte J, Tekmal R, Naud P, Edelweiss M, Valente P, et al. Computer-assisted immunohistochemical analysis of cervical cancer biomarkers using low-cost and simple software. Appl Immunohistochem Mol Morphol. 2007;15:456-62 pubmed |
- immunohistochemistry; mouse
| Funahashi H, Satake M, Dawson D, Huynh N, Reber H, Hines O, et al. Delayed progression of pancreatic intraepithelial neoplasia in a conditional Kras(G12D) mouse model by a selective cyclooxygenase-2 inhibitor. Cancer Res. 2007;67:7068-71 pubmed |
- immunohistochemistry; human; 1:50
| Longatto Filho A, Pinheiro C, Pereira S, Etlinger D, Moreira M, Jubé L, et al. Lymphatic vessel density and epithelial D2-40 immunoreactivity in pre-invasive and invasive lesions of the uterine cervix. Gynecol Oncol. 2007;107:45-51 pubmed |
- immunohistochemistry; human
| Neppelberg E, Johannessen A. DNA content, Cyclooxygenase-2 expression and loss of E-cadherin expression do not predict risk of malignant transformation in oral lichen planus. Eur Arch Otorhinolaryngol. 2007;264:1223-30 pubmed |
| Mohammed A, Celentano A, Paolini R, Low J, Silke J, O Reilly L, et al. High molecular weight hyaluronic acid drastically reduces chemotherapy-induced mucositis and apoptotic cell death. Cell Death Dis. 2023;14:453 pubmed publisher |
| Li Y, Zhang C, Zhao Z. CircSLCO3A1 depletion ameliorates lipopolysaccharide-induced inflammation and apoptosis of human pulmonary alveolar epithelial cells through the miR-424-5p/HMGB3 pathway. Mol Cell Toxicol. 2023;:1-12 pubmed publisher |
| Yang M, Lennikov A, Chang K, Ashok A, Lee C, Cho K, et al. Transcorneal but not transpalpebral electrical stimulation disrupts mucin homeostasis of the ocular surface. BMC Ophthalmol. 2022;22:490 pubmed publisher |
| Lennikov A, Yang M, Chang K, Pan L, Saddala M, Lee C, et al. Direct modulation of microglial function by electrical field. Front Cell Dev Biol. 2022;10:980775 pubmed publisher |
| Zhou Q, Zhang L. MicroRNA-183-5p protects human derived cell line SH-SY5Y cells from mepivacaine-induced injury. Bioengineered. 2021;12:3177-3187 pubmed publisher |
| Hikage F, Lennikov A, Mukwaya A, Lachota M, Ida Y, Utheim T, et al. NF-κB activation in retinal microglia is involved in the inflammatory and neovascularization signaling in laser-induced choroidal neovascularization in mice. Exp Cell Res. 2021;403:112581 pubmed publisher |
| Grancieri M, Martino H, Gonzalez de Mejia E. Protein Digests and Pure Peptides from Chia Seed Prevented Adipogenesis and Inflammation by Inhibiting PPARγ and NF-κB Pathways in 3T3L-1 Adipocytes. Nutrients. 2021;13: pubmed publisher |
| Mariod A, Salama S. The Efficacy of Processing Strategies on the Gastroprotective Potentiality of Chenopodium quinoa Seeds. ScientificWorldJournal. 2020;2020:6326452 pubmed publisher |
| Saddala M, Lennikov A, Mukwaya A, Yang Y, Hill M, Lagali N, et al. Discovery of novel L-type voltage-gated calcium channel blockers and application for the prevention of inflammation and angiogenesis. J Neuroinflammation. 2020;17:132 pubmed publisher |
| Patan Zugaj B, Egerbacher M, Licka T. Endotoxin-induced changes in expression of cyclooxygenase isoforms in the lamellar tissue of extracorporeally haemoperfused equine limbs. Anat Histol Embryol. 2020;49:597-605 pubmed publisher |
| Cherng J, Hsu Y, Liu C, Tang S, Sartika D, Chang S, et al. Activities of Ca2+-related ion channels during the formation of kidney stones in an infection-induced urolithiasis rat model. Am J Physiol Renal Physiol. 2019;317:F1342-F1349 pubmed publisher |
| Lennikov A, Saddala M, Mukwaya A, Tang S, Huang H. Autoimmune-Mediated Retinopathy in CXCR5-Deficient Mice as the Result of Age-Related Macular Degeneration Associated Proteins Accumulation. Front Immunol. 2019;10:1903 pubmed publisher |
| Grancieri M, Martino H, Gonzalez de Mejia E. Chia (Salvia hispanica L.) Seed Total Protein and Protein Fractions Digests Reduce Biomarkers of Inflammation and Atherosclerosis in Macrophages In Vitro. Mol Nutr Food Res. 2019;63:e1900021 pubmed publisher |
| Guo X, Liu W, Yang D, Shen Z, Qiu Z, Jin M, et al. Hepatitis C virus infection induces endoplasmic reticulum stress and apoptosis in human fetal liver stem cells. J Pathol. 2019;248:155-163 pubmed publisher |
| Zhang M, Wang S, Wang Y, Zhang Y, Ming Hao C, Harris R. Renal Medullary Interstitial COX-2 (Cyclooxygenase-2) Is Essential in Preventing Salt-Sensitive Hypertension and Maintaining Renal Inner Medulla/Papilla Structural Integrity. Hypertension. 2018;72:1172-1179 pubmed publisher |
| Pan Y, Long X, Yi R, Zhao X. Polyphenols in Liubao Tea Can Prevent CCl₄-Induced Hepatic Damage in Mice through Its Antioxidant Capacities. Nutrients. 2018;10: pubmed publisher |
| Gautam S, Rawat A, Sammi S, Roy S, Singh M, Devi U, et al. DuCLOX-2/5 Inhibition Attenuates Inflammatory Response and Induces Mitochondrial Apoptosis for Mammary Gland Chemoprevention. Front Pharmacol. 2018;9:314 pubmed publisher |
| Sućurović S, Nikolic T, Brosens J, Mulac Jericevic B. Spatial and Temporal Analyses of FGF9 Expression During Early Pregnancy. Cell Physiol Biochem. 2017;42:2318-2329 pubmed publisher |
| Nagy E, Vajda E, Vari C, Sipka S, Fárr A, Horváth E. Meloxicam ameliorates the cartilage and subchondral bone deterioration in monoiodoacetate-induced rat osteoarthritis. Peerj. 2017;5:e3185 pubmed publisher |
| Yang T, Hsu P, Meng M, Su C. Supplement of 5-hydroxytryptophan before induction suppresses inflammation and collagen-induced arthritis. Arthritis Res Ther. 2015;17:364 pubmed publisher |
| UgraÅŸ N, Özgün G, OcakoÄŸlu G, Yerci Ã, Öztürk E. Relationship between HER-2, COX-2, p53 and clinicopathologic features in gastric adenocarcinoma. Do these biomarkers have any prognostic significance?. Turk J Gastroenterol. 2014;25 Suppl 1:176-81 pubmed publisher |
| Németh I, Tiszlavicz L. Biphenotypic surface epithelial cells in the gastrointestinal tube with mixed epithelial-myofibroblastic differentiation: a paradigm. Pathol Oncol Res. 2012;18:391-6 pubmed publisher |
| Loong S, Hwang J, Li H, Wee J, Yap S, Chua M, et al. Weak expression of cyclooxygenase-2 is associated with poorer outcome in endemic nasopharyngeal carcinoma: analysis of data from randomized trial between radiation alone versus concurrent chemo-radiation (SQNP-01). Radiat Oncol. 2009;4:23 pubmed publisher |
