This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Vimentin Monoclonal Antibody (SP20)
catalog :
MA5-14564
quantity :
500 µL
price :
US 520
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
SP20
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 28
Reference
Bhagirath D, Zhao X, Mirza S, West W, Band H, Band V. Mutant PIK3CA Induces EMT in a Cell Type Specific Manner. PLoS ONE. 2016;11:e0167064 pubmed publisher
Harkness L, Zaher W, Ditzel N, Isa A, Kassem M. CD146/MCAM defines functionality of human bone marrow stromal stem cell populations. Stem Cell Res Ther. 2016;7:4 pubmed publisher
Bhagirath D, Zhao X, West W, Qiu F, Band H, Band V. Cell type of origin as well as genetic alterations contribute to breast cancer phenotypes. Oncotarget. 2015;6:9018-30 pubmed
Chen Q, Gu Y, Liu B. Clinicopathological characteristics of kidney mucinous tubular and spindle cell carcinoma. Int J Clin Exp Pathol. 2015;8:1007-12 pubmed
Treloar K, Simpson M, Haridas P, Manton K, Leavesley D, McElwain D, et al. Multiple types of data are required to identify the mechanisms influencing the spatial expansion of melanoma cell colonies. BMC Syst Biol. 2013;7:137 pubmed publisher
Gremel G, Bergman J, Djureinovic D, Edqvist P, Maindad V, Bharambe B, et al. A systematic analysis of commonly used antibodies in cancer diagnostics. Histopathology. 2014;64:293-305 pubmed publisher
Burden Gulley S, Zhou Z, Craig S, Lu Z, Brady Kalnay S. Molecular Magnetic Resonance Imaging of Tumors with a PTPµ Targeted Contrast Agent. Transl Oncol. 2013;6:329-37 pubmed
Mace T, Ameen Z, Collins A, Wojcik S, Mair M, Young G, et al. Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner. Cancer Res. 2013;73:3007-18 pubmed publisher
Schoppmann S, Jesch B, Riegler M, Maroske F, Schwameis K, Jomrich G, et al. Podoplanin expressing cancer associated fibroblasts are associated with unfavourable prognosis in adenocarcinoma of the esophagus. Clin Exp Metastasis. 2013;30:441-6 pubmed publisher
Hegde G, de la Cruz C, Eastham Anderson J, Zheng Y, Sweet Cordero E, Jackson E. Residual tumor cells that drive disease relapse after chemotherapy do not have enhanced tumor initiating capacity. PLoS ONE. 2012;7:e45647 pubmed publisher
Majumdar K, Tyagi I, Saran R, Sakhuja P, Sharma A. Medulloblastoma with focal divergent/teratoid differentiation. Brain Tumor Pathol. 2013;30:50-6 pubmed publisher
Pavlakis K, Vrekoussis T, Messini I, Voulgaris Z, Chrysanthakis D, Yiannou P, et al. Mucinous epithelial lesions in endometrial curettage material: a diagnostic challenge. Appl Immunohistochem Mol Morphol. 2012;20:607-13 pubmed publisher
Irizarry Rovira A, Lynch S, David M, Ramos Vara J. Gonadoblastoma in the ovaries of a lesser galago (Galago senegalensis braccatus). J Comp Pathol. 2012;147:204-8 pubmed publisher
Zhao X, Malhotra G, Band H, Band V. Derivation of myoepithelial progenitor cells from bipotent mammary stem/progenitor cells. PLoS ONE. 2012;7:e35338 pubmed publisher
Yin W, Li J, Chan J. Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review. Diagn Pathol. 2012;7:39 pubmed publisher
Haug K, Azqueta A, Johnsen Soriano S, Shahdadfar A, Drolsum L, Moe M, et al. Donor cornea transfer from Optisol GS to organ culture storage: a two-step procedure to increase donor tissue lifespan. Acta Ophthalmol. 2013;91:219-25 pubmed publisher
Lupu Meiri M, Geras Raaka E, Lupu R, Shapira H, Sandbank J, Segal L, et al. Knock-down of plasminogen-activator inhibitor-1 enhances expression of E-cadherin and promotes epithelial differentiation of human pancreatic adenocarcinoma cells. J Cell Physiol. 2012;227:3621-8 pubmed publisher
Durkes A, Garner M, Juan Sallés C, Ramos Vara J. Immunohistochemical characterization of nonhuman primate ovarian sex cord-stromal tumors. Vet Pathol. 2012;49:834-8 pubmed publisher
Kaur H, Phillips Mason P, Burden Gulley S, Kerstetter Fogle A, Basilion J, Sloan A, et al. Cadherin-11, a marker of the mesenchymal phenotype, regulates glioblastoma cell migration and survival in vivo. Mol Cancer Res. 2012;10:293-304 pubmed publisher
Ersoz S, Turgutalp H, Mungan S, Güvendı G, Guven S. Cotyledonoid leiomyoma of uterus: a case report. Turk Patoloji Derg. 2011;27:257-60 pubmed publisher
Dmitrieva N, Yu L, Viapiano M, Cripe T, Chiocca E, Glorioso J, et al. Chondroitinase ABC I-mediated enhancement of oncolytic virus spread and antitumor efficacy. Clin Cancer Res. 2011;17:1362-72 pubmed publisher
Yu G, Qu G, Kong L, Pan X, Wang W, Lv J. Primary myoepithelial carcinoma of the larynx: case report and review of the literature. Pathol Res Pract. 2011;207:127-30 pubmed publisher
Gerbal Chaloin S, Duret C, Raulet E, Navarro F, Blanc P, Ramos J, et al. Isolation and culture of adult human liver progenitor cells: in vitro differentiation to hepatocyte-like cells. Methods Mol Biol. 2010;640:247-60 pubmed publisher
Eisenthal A, Trejo L, Shtabsky A, Bedny F, Brazowski E. A novel assessment of the quality of immunohistostaining overcomes the limitations of current methods. Pathol Res Pract. 2008;204:323-8 pubmed publisher
Liu H, Fan Q, Zhang Z, Li X, Yu H, Meng F. Basal-HER2 phenotype shows poorer survival than basal-like phenotype in hormone receptor-negative invasive breast cancers. Hum Pathol. 2008;39:167-74 pubmed
Dilbaz B, Bayoglu Y, Oral S, Cavusoglu D, Uluoglu O, Dilbaz S. Laparoscopic resection of urinary bladder paraganglioma: a case report. Surg Laparosc Endosc Percutan Tech. 2006;16:58-61 pubmed
Dekel B, Shezen E, Even Tov Friedman S, Katchman H, Margalit R, Nagler A, et al. Transplantation of human hematopoietic stem cells into ischemic and growing kidneys suggests a role in vasculogenesis but not tubulogenesis. Stem Cells. 2006;24:1185-93 pubmed
Valkova N, Yunis R, Mak S, Kang K, Kültz D. Nek8 mutation causes overexpression of galectin-1, sorcin, and vimentin and accumulation of the major urinary protein in renal cysts of jck mice. Mol Cell Proteomics. 2005;4:1009-18 pubmed
product information
Product Type :
Antibody
Product Name :
Vimentin Monoclonal Antibody (SP20)
Catalog # :
MA5-14564
Quantity :
500 µL
Price :
US 520
Clonality :
Monoclonal
Host :
Rabbit
Reactivity :
Human
Applications :
Flow Cytometry: 1:100, Immunocytochemistry: 1:1000, Immunofluorescence: 1:1000, Immunohistochemistry (Frozen): 1:20, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:100-1:500
Species :
Human
Clone :
SP20
Isotype :
IgG
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development. During the development process, vimentin is exchanged for new, tissue-specific IFPs. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.
Immunogen :
Recombinant protein encoding human vimentin
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:100, Immunocytochemistry: 1:1000, Immunofluorescence: 1:1000, Immunohistochemistry (Frozen): 1:20, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:100-1:500
Aliases :
cb28; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; Vim; VIME; Vimentin
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA