Placental Alkaline Phosphatase Monoclonal Antibody (SP15) | Invitrogen MA5-14544 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Placental Alkaline Phosphatase Monoclonal Antibody (SP15)

catalog :

MA5-14544

quantity :

500µL

price :

375.00 USD

clonality :

monoclonal

host :

domestic rabbit

conjugate :

clone name :

SP15

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human	Sakaguchi K, Matsuda K, Suzuki H, Yamamoto N, Kondo Y, Ando T, et al. Testicular yolk sac tumor of myxomatous, reticular, and polyvesicular vitelline type in a newborn calf. J Vet Diagn Invest. 2013;25:811-5 pubmed publisher
immunohistochemistry; human; 1:50	Stacher E, Beham Schmid C, Terpe H, Simiantonaki N, Popper H. Pulmonary histiocytic sarcoma mimicking pulmonary Langerhans cell histiocytosis in a young adult presenting with spontaneous pneumothorax: a potential diagnostic pitfall. Virchows Arch. 2009;455:187-90 pubmed publisher
immunohistochemistry; human	Russell M, Flynt F, Harroff A, Fadare O. Dedifferentiated Liposarcoma of the Retroperitoneum with Extensive Leiomyosarcomatous Differentiation and beta-Human Chorionic Gonadotropin Production. Sarcoma. 2008;2008:658090 pubmed publisher
immunohistochemistry; human; 1:300	Lau S, Weiss L, Chu P. Association of intratubular seminoma and intratubular embryonal carcinoma with invasive testicular germ cell tumors. Am J Surg Pathol. 2007;31:1045-9 pubmed
immunohistochemistry; human; 1:50 western blot; human	Li Y, Tabatabai Z, Lee T, Hatakeyama S, Ohyama C, Chan W, et al. The Y-encoded TSPY protein: a significant marker potentially plays a role in the pathogenesis of testicular germ cell tumors. Hum Pathol. 2007;38:1470-81 pubmed

product information

Product Type :

Antibody

Product Name :

Placental Alkaline Phosphatase Monoclonal Antibody (SP15)

Catalog # :

MA5-14544

Quantity :

500µL

Price (USD) :

375.00 USD

Clonality :

Monoclonal

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:50

Species :

Human

Clone :

SP15

Isotype :

IgG

Storage :

4° C

Description :

Placental Alkaline Phosphatase plays an important role in the regulation of specific inflammatory disease processes. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney for this form of alkaline phosphatase have been well characterized. Placental Alkaline Phosphatase reacts with a membrane-bound isoenzyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. Placental Alkaline Phosphatase is useful in the identification of testicular germ cell tumors. Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express epithelial membrane antigen (EMA). A proposed function of Placental Alkaline Phosphatase is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. Placental Alkaline Phosphatase has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of hypophosphatasia can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.

Immunogen :

Recombinant protein encoding human Placental Alkaline Phosphatase (PLAP)

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50

Aliases :

Alkaline phosphatase Regan isozyme; alkaline phosphatase, placental; alkaline phosphatase, placental type; alkaline phosphomonoesterase; ALP; ALPP; AP-TNAP; DOA1; FLJ11281; FLJ40094; FLJ61142; FLJ93059; glycerophosphatase; HOPS; MGC161443; MGC167935; P PLAP; PALP; PLA2P; PLAA; Placental alkaline phosphatase 1; PLAP; PLAP-1; Regan isozyme; TNAP; TNSALP