Chromogranin A Monoclonal Antibody (SP12) | Invitrogen MA5-14536 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Chromogranin A Monoclonal Antibody (SP12)

catalog :

MA5-14536

quantity :

500 uL

price :

US 480.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

SP12

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
western blot; rat; loading ...; fig 8c	Santos M, Anderson C, Neschen S, Zumbrennen Bullough K, Romney S, Kahle Stephan M, et al. Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification. Nat Commun. 2020;11:296 pubmed publisher
immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1e	Deng Y, Chen X, Ye Y, Shi X, Zhu K, Huang L, et al. Histological characterisation and prognostic evaluation of 62 gastric neuroendocrine carcinomas. Contemp Oncol (Pozn). 2016;20:311-9 pubmed publisher
immunohistochemistry; human; 1:50	Tonyali S, Yazici S, Yeşilırmak A, Ergen A. The Ewing's Sarcoma Family of Tumors of Urinary Bladder: A Case Report and Review of the Literature. Balkan Med J. 2016;33:462-6 pubmed publisher
immunohistochemistry; human; 1:100	Horváth E, Gozar H, Chira L, Dunca I, Kiss E, Pávai Z. Insulinoma diagnosed as drug-refractory epilepsy in an adolescent boy: a case report. Rom J Morphol Embryol. 2013;54:1147-51 pubmed
immunohistochemistry; human; 1:200	Hasegawa T, Yamao K, Hijioka S, Bhatia V, Mizuno N, Hara K, et al. Evaluation of Ki-67 index in EUS-FNA specimens for the assessment of malignancy risk in pancreatic neuroendocrine tumors. Endoscopy. 2014;46:32-8 pubmed publisher
immunohistochemistry; human; 1:100	Zhao L, Luo J, Zhang H, Da J. Pigmented paraganglioma of the kidney: a case report. Diagn Pathol. 2012;7:77 pubmed publisher
immunohistochemistry; human; 1:200	Yin W, Li J, Chan J. Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review. Diagn Pathol. 2012;7:39 pubmed publisher
immunohistochemistry; human; 1:200	Alvarenga C, Lopes J, Vinagre J, Paravidino P, Alvarenga M, Prando A, et al. Paraganglioma of seminal vesicle and chromophobe renal cell carcinoma: a case report and literature review. Sao Paulo Med J. 2012;130:57-60 pubmed
immunohistochemistry; human; 1:200	Terris B, Genevay M, Rouquette A, Audebourg A, Mentha G, Dousset B, et al. Acinar cell carcinoma: a possible diagnosis in patients without intrapancreatic tumour. Dig Liver Dis. 2011;43:971-4 pubmed publisher
immunohistochemistry; human	Sagnak L, Topaloglu H, Gucuk O, Han U, Ersoy H. Skip metastase on the left neck lymph nodes of the prostatic adenocarcinoma with neuroendocrine differentiation and accompanying thyroid micropapillary carcinoma. Pathol Oncol Res. 2008;14:493-5 pubmed publisher
	Aigha I, Memon B, Elsayed A, Abdelalim E. Differentiation of human pluripotent stem cells into two distinct NKX6.1 populations of pancreatic progenitors. Stem Cell Res Ther. 2018;9:83 pubmed publisher
	Memon B, Karam M, Al Khawaga S, Abdelalim E. Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1. Stem Cell Res Ther. 2018;9:15 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Chromogranin A Monoclonal Antibody (SP12)

Catalog # :

MA5-14536

Quantity :

500 uL

Price :

US 480.00

Clonality :

Monoclonal

Host :

Rabbit

Reactivity :

Human, Rat

Applications :

Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:500-1:5,000

Species :

Human, Rat

Clone :

SP12

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.

Immunogen :

Recombinant protein encoding human chromogranin A

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:500-1:5,000

Aliases :

AL-11; AL26; Beta-granin; betagranin (N-terminal fragment of chromogranin A); catestatin; CgA; CHGA; ChrA; chromofungin; chromogranin A; chromogranin A (parathyroid secretory protein 1); chromogranin A precursor; chromogranin-A; CTNNB; DKFZp686D02253; EA-92; ER-37; ES-43; FLJ25606; FLJ37923; GE-25; GR-44; GV-19; LF-19; LOW QUALITY PROTEIN: chromogranin-A; MGC105435; Pancreastatin; Parastatin; parathyroid secretory protein 1; p-Glu serpinin precursor; pituitary secretory protein I; Serpinin; Serpinin-RRG; SL21; SP-I; SS-18; Vasostatin I; Vasostatin II; Vasostatin-1; Vasostatin-2; WA-8; WE-14

more info or order :

Invitrogen product webpage