product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Cyclin D1 Recombinant Rabbit Monoclonal Antibody (SP4)
catalog :
MA5-14512
quantity :
500 uL
price :
US 530.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
SP4
reactivity :
baboons, African green monkey, human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Invitrogen product webpage
citations: 338
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:400; loading ...; fig 2c
Li H, Kurtzeborn K, Kupari J, Gui Y, Siefker E, Lu B, et al. Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF. Development. 2021;148: pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig ev2d
Di Matteo F, Pipicelli F, Kyrousi C, Tovecci I, Penna E, Crispino M, et al. Cystatin B is essential for proliferation and interneuron migration in individuals with EPM1 epilepsy. EMBO Mol Med. 2020;12:e11419 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig s17b
Ruess D, Heynen G, Ciecielski K, Ai J, Berninger A, Kabacaoglu D, et al. Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase. Nat Med. 2018;24:954-960 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3d
Lazaro S, Perez Crespo M, Enguita A, Hernandez P, Martínez Palacio J, Oteo M, et al. Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation. Oncotarget. 2017;8:4373-4386 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 4
Walline H, Carey T, Goudsmit C, Bellile E, D Souza G, Peterson L, et al. High-Risk HPV, Biomarkers, and Outcome in Matched Cohorts of Head and Neck Cancer Patients Positive and Negative for HIV. Mol Cancer Res. 2017;15:179-188 pubmed publisher
  • western blot; mouse; 1:250; loading ...; fig 9a
Fujimura K, Mitsuhashi T, Shibata S, Shimozato S, Takahashi T. In Utero Exposure to Valproic Acid Induces Neocortical Dysgenesis via Dysregulation of Neural Progenitor Cell Proliferation/Differentiation. J Neurosci. 2016;36:10908-10919 pubmed
  • immunohistochemistry - paraffin section; human; loading ...; tbl 2
Soon G, Ow G, Chan H, Ng S, Wang S. Primary cardiac diffuse large B-cell lymphoma in immunocompetent patients: clinical, histologic, immunophenotypic, and genotypic features of 3 cases. Ann Diagn Pathol. 2016;24:40-6 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig 9
Zak M, van Oort T, Hendriksen F, Garcia M, Vassart G, Grolman W. LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea. Front Cell Neurosci. 2016;10:186 pubmed publisher
  • immunohistochemistry; rat; 1:250; fig 3
Doobin D, Kemal S, Dantas T, Vallee R. Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages. Nat Commun. 2016;7:12551 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
Kim Y, Jin D, Lee B, Cho E, Han J, Shim Y, et al. Overexpression of β-Catenin and Cyclin D1 is Associated with Poor Overall Survival in Patients with Stage IA-IIA Squamous Cell Lung Cancer Irrespective of Adjuvant Chemotherapy. J Thorac Oncol. 2016;11:2193-2201 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:20; fig 2e
Song J, Song L, Herrera A, Venkataraman G, Murata Collins J, Bedell V, et al. Cyclin D1 expression in peripheral T-cell lymphomas. Mod Pathol. 2016;29:1306-1312 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1g
Kurita D, Takeuchi K, Kobayashi S, Hojo A, Uchino Y, Sakagami M, et al. A cyclin D1-negative mantle cell lymphoma with an IGL-CCND2 translocation that relapsed with blastoid morphology and aggressive clinical behavior. Virchows Arch. 2016;469:471-6 pubmed publisher
  • immunohistochemistry; mouse; 1:400; loading ...; fig 4a
Urbán N, van den Berg D, Forget A, Andersen J, Demmers J, Hunt C, et al. Return to quiescence of mouse neural stem cells by degradation of a proactivation protein. Science. 2016;353:292-5 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; tbl 1
Troxell M, Higgins J. Renal cell carcinoma in kidney allografts: histologic types, including biphasic papillary carcinoma. Hum Pathol. 2016;57:28-36 pubmed publisher
  • immunocytochemistry; human; 1:10; loading ...; fig 5
Tomei P, Masola V, Granata S, Bellin G, Carratu P, Ficial M, et al. Everolimus-induced epithelial to mesenchymal transition (EMT) in bronchial/pulmonary cells: when the dosage does matter in transplantation. J Nephrol. 2016;29:881-891 pubmed
  • immunohistochemistry; human; 1:25; fig 1
Lamba Saini M, Bouzin C, Weynand B, Marbaix E. An Appraisal of Proliferation and Apoptotic Markers in Papillary Thyroid Carcinoma: An Automated Analysis. PLoS ONE. 2016;11:e0148656 pubmed publisher
  • immunocytochemistry; human; fig 2b
Kanter M, Turan G, Usta C, Usta A, Esen H, Tavlı L, et al. Survivin and cycline D1 expressions are associated with malignant potential in mucinous ovarian neoplasms. J Mol Histol. 2016;47:145-52 pubmed publisher
  • immunohistochemistry; rat; fig 1
Carabalona A, Hu D, Vallee R. KIF1A inhibition immortalizes brain stem cells but blocks BDNF-mediated neuronal migration. Nat Neurosci. 2016;19:253-62 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; fig 3e
Mayr C, Wagner A, Loeffelberger M, Brückner D, Jakab M, Berr F, et al. The BMI1 inhibitor PTC-209 is a potential compound to halt cellular growth in biliary tract cancer cells. Oncotarget. 2016;7:745-58 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4C
Fujino K, Motooka Y, Hassan W, Ali Abdalla M, Sato Y, Kudoh S, et al. Insulinoma-Associated Protein 1 Is a Crucial Regulator of Neuroendocrine Differentiation in Lung Cancer. Am J Pathol. 2015;185:3164-77 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 9
  • western blot; mouse; fig 3
Chaudhary S, Tang X, Arumugam A, Li C, Srivastava R, Weng Z, et al. Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome. Oncotarget. 2015;6:36789-814 pubmed publisher
  • immunohistochemistry; human; fig s4
Shain A, Garrido M, Botton T, Talevich E, Yeh I, Sanborn J, et al. Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway. Nat Genet. 2015;47:1194-9 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 2
Binder Gallimidi A, Fischman S, Revach B, Bulvik R, Maliutina A, Rubinstein A, et al. Periodontal pathogens Porphyromonas gingivalis and Fusobacterium nucleatum promote tumor progression in an oral-specific chemical carcinogenesis model. Oncotarget. 2015;6:22613-23 pubmed
  • immunohistochemistry - paraffin section; human; 1:100; fig 1
Jäger W, Xue H, Hayashi T, Janssen C, Awrey S, Wyatt A, et al. Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies. Oncotarget. 2015;6:21522-32 pubmed
  • immunohistochemistry - paraffin section; human
Yin C, Tang G, Lu G, Feng X, Keating M, Medeiros L, et al. Del(20q) in patients with chronic lymphocytic leukemia: a therapy-related abnormality involving lymphoid or myeloid cells. Mod Pathol. 2015;28:1130-7 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:25; fig 6
Brunner S, Weber F, Werner J, Agha A, Farkas S, Schlitt H, et al. Neuroendocrine tumors of the pancreas: a retrospective single-center analysis using the ENETS TNM-classification and immunohistochemical markers for risk stratification. BMC Surg. 2015;15:49 pubmed publisher
  • immunohistochemistry; human; 1:50; fig 2
Beca F, Pereira M, Cameselle Teijeiro J, Martins D, Schmitt F. Altered PPP2R2A and Cyclin D1 expression defines a subgroup of aggressive luminal-like breast cancer. BMC Cancer. 2015;15:285 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50
Kim Y, Jin D, Lee B, Cho E, Han J, Shim Y, et al. RARβ2 hypermethylation is associated with poor recurrence-free survival in never-smokers with adenocarcinoma of the lung. Clin Epigenetics. 2015;7:32 pubmed publisher
  • immunohistochemistry - paraffin section; human
Li Y, Hu S, Zuo Z, Hong M, Lin P, Li S, et al. CD5-positive follicular lymphoma: clinicopathologic correlations and outcome in 88 cases. Mod Pathol. 2015;28:787-98 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:10
Meykler S, Baloch Z, Barroeta J. A case of marginal zone lymphoma with extensive emperipolesis diagnosed on pleural effusion cytology with immunocytochemistry and flow cytometry. Cytopathology. 2016;27:70-2 pubmed publisher
  • immunohistochemistry; mouse; 1:50
Dabydeen S, Kang K, Díaz Cruz E, Alamri A, Axelrod M, Bouker K, et al. Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance. Carcinogenesis. 2015;36:122-32 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:10
Zhang Q, Chabot Richards D, Evans M, Spengel K, Andrews J, Kang H, et al. A retrospective study to assess the relative value of peripheral blood, bone marrow aspirate and biopsy morphology, immunohistochemical stains, and flow cytometric analysis in the diagnosis of chronic B cell lymphoproliferative neoplasms. Int J Lab Hematol. 2015;37:390-402 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
Contreras Jurado C, García Serrano L, Martínez Fernández M, Ruiz Llorente L, Paramio J, Aranda A. Impaired hair growth and wound healing in mice lacking thyroid hormone receptors. PLoS ONE. 2014;9:e108137 pubmed publisher
  • immunohistochemistry; African green monkey; 1:80
Dumitrescu A, Aberdeen G, Pepe G, Albrecht E. Placental estrogen suppresses cyclin D1 expression in the nonhuman primate fetal adrenal cortex. Endocrinology. 2014;155:4774-84 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50
Inada A, Inada O, Fujii N, Fujishima K, Inai T, Fujii H, et al. ?-cell induction in vivo in severely diabetic male mice by changing the circulating levels and pattern of the ratios of estradiol to androgens. Endocrinology. 2014;155:3829-42 pubmed publisher
  • western blot; mouse
Yu W, Bonnet M, Farso M, Ma K, Chabot J, Martin E, et al. The expression of apoptosis inducing factor (AIF) is associated with aging-related cell death in the cortex but not in the hippocampus in the TgCRND8 mouse model of Alzheimer's disease. BMC Neurosci. 2014;15:73 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig 7b
Alanis D, Chang D, Akiyama H, Krasnow M, Chen J. Two nested developmental waves demarcate a compartment boundary in the mouse lung. Nat Commun. 2014;5:3923 pubmed publisher
  • immunohistochemistry; mouse
  • western blot; mouse
Tane S, Kubota M, Okayama H, Ikenishi A, Yoshitome S, Iwamoto N, et al. Repression of cyclin D1 expression is necessary for the maintenance of cell cycle exit in adult mammalian cardiomyocytes. J Biol Chem. 2014;289:18033-44 pubmed publisher
  • immunohistochemistry; human
Bongiovanni M, Mazzucchelli L, Giovanella L, Frattini M, Pusztaszeri M. Well-differentiated follicular patterned tumors of the thyroid with high-grade features can metastasize in the absence of capsular or vascular invasion: report of a case. Int J Surg Pathol. 2014;22:749-56 pubmed publisher
  • immunohistochemistry; human; 1:40
van den Brand M, Hoevenaars B, Sigmans J, Meijer J, van Cleef P, Groenen P, et al. Sequential immunohistochemistry: a promising new tool for the pathology laboratory. Histopathology. 2014;65:651-7 pubmed publisher
  • immunohistochemistry; human; 1:50
Chung J, Noh H, Park K, Choi E, Han A. Longer survival in patients with breast cancer with cyclin d1 over-expression after tumor recurrence: longer, but occupied with disease. J Breast Cancer. 2014;17:47-53 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
Kiszner G, Wichmann B, Nemeth I, Varga E, Meggyeshazi N, Teleki I, et al. Cell cycle analysis can differentiate thin melanomas from dysplastic nevi and reveals accelerated replication in thick melanomas. Virchows Arch. 2014;464:603-12 pubmed publisher
  • immunohistochemistry; human; 1:50
Min H, Kim J, Ryoo I, Jung S, Jung C. The role of core needle biopsy in the preoperative diagnosis of follicular neoplasm of the thyroid. APMIS. 2014;122:993-1000 pubmed publisher
  • western blot; human; 1:1000
Scharfmann R, Pechberty S, Hazhouz Y, von Bülow M, Bricout Neveu E, Grenier Godard M, et al. Development of a conditionally immortalized human pancreatic ? cell line. J Clin Invest. 2014;124:2087-98 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Li J, Bai X, Zou Y, Hao Y, Xu X. Aberration of the Wnt signaling pathway in pulmonary fatal adenocarcinoma: a case report. Chin J Cancer Res. 2014;26:E13-6 pubmed publisher
  • immunohistochemistry; human
Bergshoeff V, Van der Heijden S, Haesevoets A, Litjens S, Bot F, Voogd A, et al. Chromosome instability predicts progression of premalignant lesions of the larynx. Pathology. 2014;46:216-24 pubmed publisher
  • immunohistochemistry - paraffin section; human
Neumeister V, Parisi F, England A, Siddiqui S, Anagnostou V, Zarrella E, et al. A tissue quality index: an intrinsic control for measurement of effects of preanalytical variables on FFPE tissue. Lab Invest. 2014;94:467-74 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 3e
  • immunohistochemistry - paraffin section; mouse; fig 2a
  • western blot; mouse
Berkenkamp B, Susnik N, Baisantry A, Kuznetsova I, Jacobi C, Sörensen Zender I, et al. In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells. PLoS ONE. 2014;9:e88071 pubmed publisher
  • western blot; mouse
Marttinen M, Pajari A, Paivarinta E, Storvik M, Marttinen P, Nurmi T, et al. Plant sterol feeding induces tumor formation and alters sterol metabolism in the intestine of Apc(Min) mice. Nutr Cancer. 2014;66:259-69 pubmed publisher
  • immunohistochemistry; human; 1:100
Elesawy B, Abd El Hafez A, Shawky A, Arafa M. Immunohistochemistry-based subtyping of breast carcinoma in Egyptian women: a clinicopathologic study on 125 patients. Ann Diagn Pathol. 2014;18:21-6 pubmed publisher
  • immunocytochemistry; mouse
Bizen N, Inoue T, Shimizu T, Tabu K, Kagawa T, Taga T. A growth-promoting signaling component cyclin D1 in neural stem cells has antiastrogliogenic function to execute self-renewal. Stem Cells. 2014;32:1602-15 pubmed publisher
  • immunocytochemistry; human
Spencer S, Cappell S, Tsai F, Overton K, Wang C, Meyer T. The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit. Cell. 2013;155:369-83 pubmed publisher
  • immunohistochemistry; human
Wang S, Tzankov A, Xu Monette Z, Hoeller S, Wang S, Richards K, et al. Clonally related composite follicular lymphoma and mantle cell lymphoma with clinicopathologic features and biological implications. Hum Pathol. 2013;44:2658-67 pubmed publisher
  • immunohistochemistry; human
Rasmussen P. Diffuse large B-cell lymphoma and mantle cell lymphoma of the ocular adnexal region, and lymphoma of the lacrimal gland: an investigation of clinical and histopathological features. Acta Ophthalmol. 2013;91 Thesis 5:1-27 pubmed publisher
  • western blot; dogs; 1:200; fig 7
  • western blot; human; 1:200; fig 7
Mudaliar M, Haggart R, Miele G, Sellar G, Tan K, Goodlad J, et al. Comparative gene expression profiling identifies common molecular signatures of NF-?B activation in canine and human diffuse large B cell lymphoma (DLBCL). PLoS ONE. 2013;8:e72591 pubmed publisher
  • immunohistochemistry; human; 1:25
Gröbe A, Eichhorn W, Fraederich M, Kluwe L, Vashist Y, Wikner J, et al. Immunohistochemical and FISH analysis of EGFR and its prognostic value in patients with oral squamous cell carcinoma. J Oral Pathol Med. 2014;43:205-10 pubmed publisher
  • immunohistochemistry; mouse
Zhu S, Mott R, Fry E, Taneja P, Kulik G, Sui G, et al. Cooperation between Dmp1 loss and cyclin D1 overexpression in breast cancer. Am J Pathol. 2013;183:1339-1350 pubmed publisher
  • immunohistochemistry; mouse; 1:500
Pribluda A, Elyada E, Wiener Z, Hamza H, Goldstein R, Biton M, et al. A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism. Cancer Cell. 2013;24:242-56 pubmed publisher
  • immunohistochemistry; mouse; 1:300
Nobs L, Nestel S, Kulik A, Nitsch C, Atanasoski S. Cyclin D1 is required for proliferation of Olig2-expressing progenitor cells in the injured cerebral cortex. Glia. 2013;61:1443-55 pubmed publisher
  • western blot; mouse
Pitzonka L, Wang X, Ullas S, Wolff D, Wang Y, Goodrich D. The THO ribonucleoprotein complex is required for stem cell homeostasis in the adult mouse small intestine. Mol Cell Biol. 2013;33:3505-14 pubmed publisher
  • immunohistochemistry; human; 1:80
Shin S, Lal A, De Vries S, Suzuki J, Roy R, Hwang E, et al. Florid lobular carcinoma in situ: molecular profiling and comparison to classic lobular carcinoma in situ and pleomorphic lobular carcinoma in situ. Hum Pathol. 2013;44:1998-2009 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Bradford C, Kumar B, Bellile E, Lee J, Taylor J, D SILVA N, et al. Biomarkers in advanced larynx cancer. Laryngoscope. 2014;124:179-87 pubmed publisher
  • immunohistochemistry; human
Ferrara G, Misciali C, Brenn T, Cerroni L, Kazakov D, Perasole A, et al. The impact of molecular morphology techniques on the expert diagnosis in melanocytic skin neoplasms. Int J Surg Pathol. 2013;21:483-92 pubmed publisher
  • immunohistochemistry; human; 1:75
West D, Dogan A, Quint P, Tricker Klar M, Porcher J, Ketterling R, et al. Clonally related follicular lymphomas and Langerhans cell neoplasms: expanding the spectrum of transdifferentiation. Am J Surg Pathol. 2013;37:978-86 pubmed publisher
  • immunohistochemistry; human; 1:25
Hudolin T, Kastelan Z, Ilic I, Levarda Hudolin K, Basic Jukic N, Rieken M, et al. Immunohistochemical analysis of the expression of MAGE-A and NY-ESO-1 cancer/testis antigens in diffuse large B-cell testicular lymphoma. J Transl Med. 2013;11:123 pubmed publisher
  • immunohistochemistry; mouse; 1:50
Nakles R, Kallakury B, Furth P. The PPAR? agonist efatutazone increases the spectrum of well-differentiated mammary cancer subtypes initiated by loss of full-length BRCA1 in association with TP53 haploinsufficiency. Am J Pathol. 2013;182:1976-85 pubmed publisher
  • immunohistochemistry; human; 1:100
El Hafez A, El Aaty Shawky A, Hasan B. Cyclin D1 overexpression associates with favourable prognostic factors in invasive breast carcinoma. Cancer Biomark. 2012;12:149-54 pubmed publisher
  • immunohistochemistry; mouse; 1:50
Watson A, Rahrmann E, Moriarity B, Choi K, Conboy C, Greeley A, et al. Canonical Wnt/?-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance. Cancer Discov. 2013;3:674-89 pubmed publisher
  • immunohistochemistry; mouse; 1:500
  • immunocytochemistry; human; 1:100
Noah T, Lo Y, Price A, Chen G, King E, Washington M, et al. SPDEF functions as a colorectal tumor suppressor by inhibiting β-catenin activity. Gastroenterology. 2013;144:1012-1023.e6 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:10; tbl 2
Nichele I, Zamo A, Bertolaso A, Bifari F, Tinelli M, Franchini M, et al. VR09 cell line: an EBV-positive lymphoblastoid cell line with in vivo characteristics of diffuse large B cell lymphoma of activated B-cell type. PLoS ONE. 2012;7:e52811 pubmed publisher
  • immunohistochemistry; mouse
Anttonen T, Kirjavainen A, Belevich I, Laos M, Richardson W, Jokitalo E, et al. Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood. Sci Rep. 2012;2:978 pubmed publisher
  • immunohistochemistry; human; 1:25
Butte J, Torres J, Veras E, Matsuo K, Gonen M, D Angelica M, et al. Regional differences in gallbladder cancer pathogenesis: insights from a comparison of cell cycle-regulatory, PI3K, and pro-angiogenic protein expression. Ann Surg Oncol. 2013;20:1470-81 pubmed publisher
  • immunohistochemistry; human
Hong A, Jones D, Chatfield M, Lee C, Zhang M, Clark J, et al. HPV status of oropharyngeal cancer by combination HPV DNA/p16 testing: biological relevance of discordant results. Ann Surg Oncol. 2013;20 Suppl 3:S450-8 pubmed publisher
  • immunohistochemistry; mouse; 1:200
Kopecky B, Jahan I, Fritzsch B. Correct timing of proliferation and differentiation is necessary for normal inner ear development and auditory hair cell viability. Dev Dyn. 2013;242:132-47 pubmed publisher
  • immunohistochemistry; human; 1:50
Koay M, Crook M, Stewart C. Cyclin D1, E-cadherin and beta-catenin expression in FIGO Stage IA cervical squamous carcinoma: diagnostic value and evidence for epithelial-mesenchymal transition. Histopathology. 2012;61:1125-33 pubmed publisher
  • immunohistochemistry; human; 1:200
Erovic B, Kim D, Cassol C, Goldstein D, Irish J, Asa S, et al. Prognostic and predictive markers in medullary thyroid carcinoma. Endocr Pathol. 2012;23:232-42 pubmed publisher
  • immunohistochemistry; human
Myklebust M, Li Z, Tran T, Rui H, Knudsen E, Elsaleh H, et al. Expression of cyclin D1a and D1b as predictive factors for treatment response in colorectal cancer. Br J Cancer. 2012;107:1684-91 pubmed publisher
  • immunohistochemistry; human; 1:100
Alvelos M, Vinagre J, Fonseca E, Barbosa E, Teixeira Gomes J, Sobrinho Simoes M, et al. MEN1 intragenic deletions may represent the most prevalent somatic event in sporadic primary hyperparathyroidism. Eur J Endocrinol. 2013;168:119-28 pubmed publisher
  • immunohistochemistry; human
  • western blot; human
Neumeister V, Anagnostou V, Siddiqui S, England A, Zarrella E, Vassilakopoulou M, et al. Quantitative assessment of effect of preanalytic cold ischemic time on protein expression in breast cancer tissues. J Natl Cancer Inst. 2012;104:1815-24 pubmed publisher
  • immunohistochemistry; human; 1:50
Jang K, Kim Y, Bae J, Chung M, Moon W, Kang M, et al. Expression of Cyclin D1 Is Associated with β-Catenin Expression and Correlates with Good Prognosis in Colorectal Adenocarcinoma. Transl Oncol. 2012;5:370-8 pubmed
  • immunohistochemistry; human; 1:10
Munari E, Rinaldi M, Ambrosetti A, Bonifacio M, Bonalumi A, Chilosi M, et al. Absence of TCL1A expression is a useful diagnostic feature in splenic marginal zone lymphoma. Virchows Arch. 2012;461:677-85 pubmed publisher
  • immunohistochemistry; human; 1:200
Erovic B, Harris L, Jamali M, Goldstein D, Irish J, Asa S, et al. Biomarkers of parathyroid carcinoma. Endocr Pathol. 2012;23:221-31 pubmed publisher
  • immunohistochemistry; human; 1:200
Hsieh R, Nico M, Coutinho Camillo C, Buim M, Sangueza M, Lourenço S. The CDKN2A and MAP kinase pathways: molecular roads to primary oral mucosal melanoma. Am J Dermatopathol. 2013;35:167-75 pubmed publisher
  • immunohistochemistry; mouse; 1:400
Virolainen S, Achim K, Peltopuro P, Salminen M, Partanen J. Transcriptional regulatory mechanisms underlying the GABAergic neuron fate in different diencephalic prosomeres. Development. 2012;139:3795-805 pubmed
  • immunohistochemistry; human; 1:250
Gruver A, Huba M, Dogan A, Hsi E. Fibrin-associated large B-cell lymphoma: part of the spectrum of cardiac lymphomas. Am J Surg Pathol. 2012;36:1527-37 pubmed publisher
  • western blot; mouse
Marttinen M, Paivarinta E, Storvik M, Huikko L, Luoma Halkola H, Piironen V, et al. Plant stanols induce intestinal tumor formation by up-regulating Wnt and EGFR signaling in Apc Min mice. J Nutr Biochem. 2013;24:343-52 pubmed publisher
  • immunohistochemistry; human; 1:40
Kornegoor R, Verschuur Maes A, Buerger H, Hogenes M, de Bruin P, Oudejans J, et al. Immunophenotyping of male breast cancer. Histopathology. 2012;61:1145-55 pubmed publisher
  • western blot; mouse
Ikenishi A, Okayama H, Iwamoto N, Yoshitome S, Tane S, Nakamura K, et al. Cell cycle regulation in mouse heart during embryonic and postnatal stages. Dev Growth Differ. 2012;54:731-8 pubmed publisher
  • immunohistochemistry; human
Hoeller S, Zhou Y, Kanagal Shamanna R, Xu Monette Z, Hoehn D, Bihl M, et al. Composite mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: a clinicopathologic and molecular study. Hum Pathol. 2013;44:110-21 pubmed publisher
  • immunohistochemistry; human
Nilsson C, Koliadi A, Johansson I, Ahlin C, Thorstenson S, Bergkvist L, et al. High proliferation is associated with inferior outcome in male breast cancer patients. Mod Pathol. 2013;26:87-94 pubmed publisher
  • immunohistochemistry; human; 1:25
Zhang Y, Xu Z, Wang J, Wei D, Pan X. G1/S-specific cyclin-D1 might be a prognostic biomarker for patients with laryngeal squamous cell carcinoma. Asian Pac J Cancer Prev. 2012;13:2133-7 pubmed
  • immunohistochemistry; human; 1:25
Therkildsen C, Isinger Ekstrand A, Ladelund S, Nissen A, Rambech E, Bernstein I, et al. Cancer risks and immunohistochemical profiles linked to the Danish MLH1 Lynch syndrome founder mutation. Fam Cancer. 2012;11:579-85 pubmed publisher
  • immunohistochemistry; human
Toru S, Bilezikci B. Early changes in carcinogenesis of colorectal adenomas. West Indian Med J. 2012;61:10-6 pubmed
  • immunohistochemistry; human; 1:40
Adam P, Schiefer A, Prill S, Henopp T, Quintanilla Martinez L, Bösmüller H, et al. Incidence of preclinical manifestations of mantle cell lymphoma and mantle cell lymphoma in situ in reactive lymphoid tissues. Mod Pathol. 2012;25:1629-36 pubmed publisher
  • immunohistochemistry; human
Tang L, Contractor T, Clausen R, Klimstra D, Du Y, Allen P, et al. Attenuation of the retinoblastoma pathway in pancreatic neuroendocrine tumors due to increased cdk4/cdk6. Clin Cancer Res. 2012;18:4612-20 pubmed publisher
  • immunohistochemistry; human; 1:100
Assmann G, Kappler R, Zeindl Eberhart E, Schmid I, Häberle B, Graeb C, et al. ?-Catenin mutations in 2 nested stromal epithelial tumors of the liver--a neoplasia with defective mesenchymal-epithelial transition. Hum Pathol. 2012;43:1815-27 pubmed publisher
  • immunohistochemistry; human; 1:200
Erovic B, Al Habeeb A, Harris L, Goldstein D, Kim D, Ghazarian D, et al. Identification of novel target proteins in sebaceous gland carcinoma. Head Neck. 2013;35:642-8 pubmed publisher
  • immunohistochemistry; human; 1:25
Calderaro J, Moroch J, Pierron G, Pedeutour F, Grison C, Maille P, et al. SMARCB1/INI1 inactivation in renal medullary carcinoma. Histopathology. 2012;61:428-35 pubmed publisher
  • immunohistochemistry; human; 1:800
Meijer D, de Jong D, Pansuriya T, van den Akker B, Picci P, Szuhai K, et al. Genetic characterization of mesenchymal, clear cell, and dedifferentiated chondrosarcoma. Genes Chromosomes Cancer. 2012;51:899-909 pubmed publisher
  • immunohistochemistry; human
Hsiao S, Cortada I, Colomo L, Ye H, Liu H, Kuo S, et al. SOX11 is useful in differentiating cyclin D1-positive diffuse large B-cell lymphoma from mantle cell lymphoma. Histopathology. 2012;61:685-93 pubmed publisher
  • immunohistochemistry; human
Rasmussen P, Ralfkiaer E, Prause J, Sjö L, Toft P, Siersma V, et al. Diffuse large B-cell lymphoma of the ocular adnexal region: a nation-based study. Acta Ophthalmol. 2013;91:163-9 pubmed publisher
  • western blot; human; 1:1000
  • immunohistochemistry; mouse
Joshi A, Wang H, Jiang G, Douglas W, Chan J, Korach K, et al. Endometrial tumorigenesis in Pten(+/-) mice is independent of coexistence of estrogen and estrogen receptor ?. Am J Pathol. 2012;180:2536-47 pubmed publisher
  • immunohistochemistry; human
Speisky D, Ducès A, Bieche I, Rebours V, Hammel P, Sauvanet A, et al. Molecular profiling of pancreatic neuroendocrine tumors in sporadic and Von Hippel-Lindau patients. Clin Cancer Res. 2012;18:2838-49 pubmed publisher
  • immunohistochemistry; human
Liu W, Medeiros L, Lin P, Romaguera J, Wang S, Jorgensen J. Usefulness of flow cytometric immunophenotyping for bone marrow staging in patients with mantle cell lymphoma after therapy. Am J Clin Pathol. 2012;137:634-40 pubmed publisher
  • immunohistochemistry; human
Jaso J, Chen L, Li S, Lin P, Chen W, Miranda R, et al. CD5-positive mucosa-associated lymphoid tissue (MALT) lymphoma: a clinicopathologic study of 14 cases. Hum Pathol. 2012;43:1436-43 pubmed publisher
  • immunohistochemistry; rat; 1:500
  • western blot; rat; 1:500
Efthimiadi L, Farso M, Quirion R, Krantic S. Cyclin D1 induction preceding neuronal death via the excitotoxic NMDA pathway involves selective stimulation of extrasynaptic NMDA receptors and JNK pathway. Neurodegener Dis. 2012;10:80-91 pubmed publisher
  • immunohistochemistry; human; 1:200
Huang S, Cheng S, Chuang W, Chen I, Liao C, Wang H, et al. Cyclin D1 overexpression and poor clinical outcomes in Taiwanese oral cavity squamous cell carcinoma. World J Surg Oncol. 2012;10:40 pubmed publisher
  • immunohistochemistry; human; 1:35
Formosa R, Gruppetta M, Falzon S, Santillo G, Degaetano J, Xuereb Anastasi A, et al. Expression and clinical significance of Wnt players and survivin in pituitary tumours. Endocr Pathol. 2012;23:123-31 pubmed publisher
  • immunohistochemistry; human
Svec A, Rangaiah M, Giles M, Jaksa R, McAulay K. EBV+ diffuse large B-cell lymphoma arising within atrial myxoma. An example of a distinct primary cardiac EBV+ DLBCL of immunocompetent patients. Pathol Res Pract. 2012;208:172-6 pubmed publisher
  • immunohistochemistry; human; 1:50
Rasamny J, Allak A, Krook K, Jo V, Policarpio Nicolas M, Sumner H, et al. Cyclin D1 and FADD as biomarkers in head and neck squamous cell carcinoma. Otolaryngol Head Neck Surg. 2012;146:923-31 pubmed publisher
  • immunohistochemistry; human; 1:40
Kornegoor R, Verschuur Maes A, Buerger H, van Diest P. The 3-layered ductal epithelium in gynecomastia. Am J Surg Pathol. 2012;36:762-8 pubmed publisher
  • western blot; rat; 1:1000
Boutant M, Ramos O, Tourrel Cuzin C, Movassat J, Ilias A, Vallois D, et al. COUP-TFII controls mouse pancreatic β-cell mass through GLP-1-β-catenin signaling pathways. PLoS ONE. 2012;7:e30847 pubmed publisher
  • immunohistochemistry; mouse; 1:200
Le T, Conley K, Mead T, Rowan S, Yutzey K, Brown N. Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development. Dev Dyn. 2012;241:493-504 pubmed publisher
  • immunohistochemistry; human; 1:30
Tan L, Tan S, Tang T, Lim S, Tan D, Lim L, et al. Angioimmunoblastic T-cell lymphoma with hyperplastic germinal centres (pattern 1) shows superior survival to patterns 2 and 3: a meta-analysis of 56 cases. Histopathology. 2012;60:570-85 pubmed publisher
  • immunohistochemistry; human
Schrijvers M, Pattje W, Slagter Menkema L, Mastik M, Gibcus J, Langendijk J, et al. FADD expression as a prognosticator in early-stage glottic squamous cell carcinoma of the larynx treated primarily with radiotherapy. Int J Radiat Oncol Biol Phys. 2012;83:1220-6 pubmed publisher
  • immunohistochemistry - paraffin section; human
Zuo Z, Tang Y, Bi C, Zhang W, Zhao S, Wang X, et al. Extraosseous (extramedullary) plasmacytomas: a clinicopathologic and immunophenotypic study of 32 Chinese cases. Diagn Pathol. 2011;6:123 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50
Jung Y, Joo K, Seong D, Choi Y, Kong D, Kim Y, et al. Identification of prognostic biomarkers for glioblastomas using protein expression profiling. Int J Oncol. 2012;40:1122-32 pubmed publisher
  • immunohistochemistry; mouse
Yan Q, Feng Q, Beier F. Reduced chondrocyte proliferation, earlier cell cycle exit and increased apoptosis in neuronal nitric oxide synthase-deficient mice. Osteoarthritis Cartilage. 2012;20:144-51 pubmed publisher
  • immunohistochemistry; human
Tang A, Hauff S, Owen J, Graham M, Czerwinski M, Park J, et al. UM-SCC-104: a new human papillomavirus-16-positive cancer stem cell-containing head and neck squamous cell carcinoma cell line. Head Neck. 2012;34:1480-91 pubmed publisher
  • immunohistochemistry; human
Karlsson C, Karlsson M. Effects of long-term storage on the detection of proteins, DNA, and mRNA in tissue microarray slides. J Histochem Cytochem. 2011;59:1113-21 pubmed publisher
  • immunohistochemistry; human; 1:40
Gerhardt J, Montani M, Wild P, Beer M, Huber F, Hermanns T, et al. FOXA1 promotes tumor progression in prostate cancer and represents a novel hallmark of castration-resistant prostate cancer. Am J Pathol. 2012;180:848-61 pubmed publisher
  • immunohistochemistry; human
Woelber L, Hess S, Bohlken H, Tennstedt P, Eulenburg C, Simon R, et al. EGFR gene copy number increase in vulvar carcinomas is linked with poor clinical outcome. J Clin Pathol. 2012;65:133-9 pubmed publisher
  • immunohistochemistry; human
Guarnieri V, Baorda F, Battista C, Bisceglia M, Balsamo T, Gruppioni E, et al. A rare S33C mutation of CTNNB1 encoding ?-catenin in a parathyroid adenoma found in an Italian primary hyperparathyroid cohort. Endocrine. 2012;41:152-5 pubmed publisher
  • immunohistochemistry; human
Clement C, Potluri V, Gonzales J, Qian Y. Translocation (5; 11) in a conjunctival MALT lymphoma. Int J Clin Exp Pathol. 2011;4:722-6 pubmed
  • immunohistochemistry; mouse; 1:250; fig 2
Loponen H, Ylikoski J, Albrecht J, Pirvola U. Restrictions in cell cycle progression of adult vestibular supporting cells in response to ectopic cyclin D1 expression. PLoS ONE. 2011;6:e27360 pubmed publisher
  • immunohistochemistry; human; 1:100
Makarewicz R, Zyromska A, Andrusewicz H. Comparative analysis of biological profiles of benign prostate hyperplasia and prostate cancer as potential diagnostic, prognostic and predictive indicators. Folia Histochem Cytobiol. 2011;49:452-7 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:100
  • western blot; mouse; 1:1000
Na B, Huang Z, Wang Q, Qi Z, Tian Y, Lu C, et al. Transgenic expression of entire hepatitis B virus in mice induces hepatocarcinogenesis independent of chronic liver injury. PLoS ONE. 2011;6:e26240 pubmed publisher
  • immunohistochemistry; human; 1:25
Gauchotte G, Vigouroux C, Rech F, Battaglia Hsu S, Soudant M, Pinelli C, et al. Expression of minichromosome maintenance MCM6 protein in meningiomas is strongly correlated with histologic grade and clinical outcome. Am J Surg Pathol. 2012;36:283-91 pubmed publisher
  • western blot; mouse
Moustafa T, Fickert P, Magnes C, Guelly C, Thueringer A, Frank S, et al. Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury. Gastroenterology. 2012;142:140-151.e12 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 5
Wang G, Yan Q, Woods A, Aubrey L, Feng Q, Beier F. Inducible nitric oxide synthase-nitric oxide signaling mediates the mitogenic activity of Rac1 during endochondral bone growth. J Cell Sci. 2011;124:3405-13 pubmed publisher
  • immunohistochemistry; human; 1:250
Hill B, Weil A, Kalaycio M, Cook J. Pulmonary involvement by chronic lymphocytic leukemia/small lymphocytic lymphoma is a specific pathologic finding independent of inflammatory infiltration. Leuk Lymphoma. 2012;53:589-95 pubmed publisher
  • immunohistochemistry; human; 1:100
Perisanidis C, Perisanidis B, Wrba F, Brandstetter A, El Gazzar S, Papadogeorgakis N, et al. Evaluation of immunohistochemical expression of p53, p21, p27, cyclin D1, and Ki67 in oral and oropharyngeal squamous cell carcinoma. J Oral Pathol Med. 2012;41:40-6 pubmed publisher
  • western blot; human
Xu W, Du M, Zhao Y, Wang Q, Sun W, Chen B. ?-Tocotrienol inhibits cell viability through suppression of ?-catenin/Tcf signaling in human colon carcinoma HT-29 cells. J Nutr Biochem. 2012;23:800-7 pubmed publisher
  • immunohistochemistry; human
Sherman M, Hanson C, Hoyer J. An assessment of the usefulness of immunohistochemical stains in the diagnosis of hairy cell leukemia. Am J Clin Pathol. 2011;136:390-9 pubmed publisher
  • immunohistochemistry; human; 1:100
Vlachostergios P, Karasavvidou F, Patrikidou A, Voutsadakis I, Kakkas G, Moutzouris G, et al. p53 and cyclooxygenase-2 expression are directly associated with cyclin D1 expression in radical prostatectomy specimens of patients with hormone-naïve prostate cancer. Pathol Oncol Res. 2012;18:245-52 pubmed publisher
  • immunohistochemistry; human; 1:50
Lax S, Schauer G, Prein K, Kapitan M, Silbert D, Berghold A, et al. Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis. Int J Cancer. 2012;130:2232-9 pubmed publisher
  • immunohistochemistry; human
Bagazgoitia L, Cuevas Santos J, Juarranz A, Jaen P. Photodynamic therapy reduces the histological features of actinic damage and the expression of early oncogenic markers. Br J Dermatol. 2011;165:144-51 pubmed publisher
  • immunohistochemistry; human
Kimura Y, Sato K, Imamura Y, Arakawa F, Kiyasu J, Takeuchi M, et al. Small cell variant of mantle cell lymphoma is an indolent lymphoma characterized by bone marrow involvement, splenomegaly, and a low Ki-67 index. Cancer Sci. 2011;102:1734-41 pubmed publisher
  • immunohistochemistry; human; 1:100
de Vreeze R, van Coevorden F, Boerrigter L, Nederlof P, Haas R, Bras J, et al. Delineation of chondroid lipoma: an immunohistochemical and molecular biological analysis. Sarcoma. 2011;2011:638403 pubmed publisher
  • immunohistochemistry; human; 1:30
Acikalin M, Etiz D, Gürbüz M, Ozudogru E, Canaz F, Colak E. Prognostic significance of galectin-3 and cyclin D1 expression in undifferentiated nasopharyngeal carcinoma. Med Oncol. 2012;29:742-9 pubmed publisher
  • immunohistochemistry; human; 1:40
Huh Y, Schweighofer C, Ketterling R, Knudson R, Vega F, Kim J, et al. Chronic lymphocytic leukemia with t(14;19)(q32;q13) is characterized by atypical morphologic and immunophenotypic features and distinctive genetic features. Am J Clin Pathol. 2011;135:686-96 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Hao F, Pysz M, Curry K, Haas K, Seedhouse S, Black A, et al. Protein kinase C? signaling regulates inhibitor of DNA binding 1 in the intestinal epithelium. J Biol Chem. 2011;286:18104-17 pubmed publisher
  • immunohistochemistry; human; 1:25
Fleischmann A, Rocha C, Saxer Sekulic N, Zlobec I, Sauter G, Thalmann G. High-level cytoplasmic cyclin D1 expression in lymph node metastases from prostate cancer independently predicts early biochemical failure and death in surgically treated patients. Histopathology. 2011;58:781-9 pubmed publisher
  • immunohistochemistry; human
Canzonieri V, Barzan L, Franchin G, Vaccher E, Talamini R, Sulfaro S, et al. Alteration of G1/S transition regulators influences recurrences in head and neck squamous carcinomas. J Cell Physiol. 2012;227:233-8 pubmed publisher
  • immunohistochemistry; human; 1:100
Yu S, Chen S, Lu W, Liu T, Lin C. Expression of CD19 and lack of miR-223 distinguish extramedullary plasmacytoma from multiple myeloma. Histopathology. 2011;58:896-905 pubmed publisher
  • western blot; human; 1:1000
Pighi C, Gu T, Dalai I, Barbi S, Parolini C, Bertolaso A, et al. Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling. Cell Oncol (Dordr). 2011;34:141-53 pubmed publisher
  • immunohistochemistry; human
Schmatz A, Streubel B, Kretschmer Chott E, Puspok A, Jager U, Mannhalter C, et al. Primary follicular lymphoma of the duodenum is a distinct mucosal/submucosal variant of follicular lymphoma: a retrospective study of 63 cases. J Clin Oncol. 2011;29:1445-51 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 2
van der Weyden L, Alcolea M, Jones P, Rust A, Arends M, Adams D. Acute sensitivity of the oral mucosa to oncogenic K-ras. J Pathol. 2011;224:22-32 pubmed publisher
  • western blot; human; 1:1000
Ng C, Ng P, Lui V, Li J, Chan J, Fung K, et al. FHL2 exhibits anti-proliferative and anti-apoptotic activities in liver cancer cells. Cancer Lett. 2011;304:97-106 pubmed publisher
  • immunohistochemistry; human; 1:100
Allison K, Kandalaft P, Sitlani C, Dintzis S, Gown A. Routine pathologic parameters can predict Oncotype DX recurrence scores in subsets of ER positive patients: who does not always need testing?. Breast Cancer Res Treat. 2012;131:413-24 pubmed publisher
  • immunohistochemistry; human; 1:100
Gualco G, Klumb C, Barber G, Weiss L, Bacchi C. Pediatric lymphomas in Brazil. Clinics (Sao Paulo). 2010;65:1267-77 pubmed
  • immunohistochemistry; human; 1:100
Xu X, Sun P, Li J, Jheon S, Lee C, Chung J. Aberrant Wnt1/?-catenin expression is an independent poor prognostic marker of non-small cell lung cancer after surgery. J Thorac Oncol. 2011;6:716-24 pubmed publisher
  • immunohistochemistry; human
Lucioni M, Novara F, Riboni R, Fiandrino G, Nicola M, Kindl S, et al. CD5(-) diffuse large B-cell lymphoma with peculiar cyclin D1+ phenotype. Pathologic and molecular characterization of a single case. Hum Pathol. 2011;42:1204-8 pubmed publisher
  • immunohistochemistry; mouse; 1:125
  • western blot; mouse; 1:500
Elyada E, Pribluda A, Goldstein R, Morgenstern Y, Brachya G, Cojocaru G, et al. CKI? ablation highlights a critical role for p53 in invasiveness control. Nature. 2011;470:409-13 pubmed publisher
  • immunohistochemistry; human
Vela Chavez T, Adam P, Kremer M, Bink K, Bacon C, Menon G, et al. Cyclin D1 positive diffuse large B-cell lymphoma is a post-germinal center-type lymphoma without alterations in the CCND1 gene locus. Leuk Lymphoma. 2011;52:458-66 pubmed publisher
  • western blot; mouse
Bruggeman L, Drawz P, Kahoud N, Lin K, Barisoni L, Nelson P. TNFR2 interposes the proliferative and NF-?B-mediated inflammatory response by podocytes to TNF-?. Lab Invest. 2011;91:413-25 pubmed publisher
  • immunohistochemistry; mouse; 1:50
Torre C, Benhamouche S, Mitchell C, Godard C, Veber P, Letourneur F, et al. The transforming growth factor-? and cyclin D1 genes are direct targets of ?-catenin signaling in hepatocyte proliferation. J Hepatol. 2011;55:86-95 pubmed publisher
  • immunohistochemistry; human
Jansen C, Feuth T, Raemaekers J, Rijntjes J, Meijer J, Westenend P, et al. Protein profiling in pathology: analysis and evaluation of 239 frozen tissue biopsies for diagnosis of B-cell lymphomas. Proteomics Clin Appl. 2010;4:519-27 pubmed publisher
  • immunohistochemistry; human; 1:100
Li X, Liu M, Zhang Y, Wang J, Zheng Y, Li J, et al. CK5/6, EGFR, Ki-67, cyclin D1, and nm23-H1 protein expressions as predictors of pathological complete response to neoadjuvant chemotherapy in triple-negative breast cancer patients. Med Oncol. 2011;28 Suppl 1:S129-34 pubmed publisher
  • immunohistochemistry; human; 1:50
Nishimura I, Ohishi Y, Oda Y, Kishimoto J, Yasunaga M, Okuma E, et al. Expression and localization of E-cadherin and ?-catenin in uterine carcinosarcoma. Virchows Arch. 2011;458:85-94 pubmed publisher
  • immunohistochemistry; human; 1:25
  • immunohistochemistry; rat; 1:25
Schwensen K, Burgess J, Graf N, Alexander S, Harris D, Phillips J, et al. Early cyst growth is associated with the increased nuclear expression of cyclin D1/Rb protein in an autosomal-recessive polycystic kidney disease rat model. Nephron Exp Nephrol. 2011;117:e93-103 pubmed publisher
  • immunohistochemistry; human
Ianotto J, Tempescul A, Eveillard J, André N, Morel F, Quintin Roue I, et al. Acute dyspnoea and single tracheal localisation of mantle cell lymphoma. J Hematol Oncol. 2010;3:34 pubmed publisher
  • immunohistochemistry; mouse
Gonzalez Suarez E, Jacob A, Jones J, Miller R, Roudier Meyer M, Erwert R, et al. RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis. Nature. 2010;468:103-7 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 1, 2, 3
  • immunohistochemistry; human; 1:100
Cheuk W, Tam F, Chan A, Luk I, Yuen A, Chan W, et al. Idiopathic cervical fibrosis--a new member of IgG4-related sclerosing diseases: report of 4 cases, 1 complicated by composite lymphoma. Am J Surg Pathol. 2010;34:1678-85 pubmed publisher
  • immunohistochemistry; human; 1:100
Koo J, Shin E, Hong S. Immunohistochemical characteristics of diffuse sclerosing variant of papillary carcinoma: comparison with conventional papillary carcinoma. APMIS. 2010;118:744-52 pubmed publisher
  • immunohistochemistry; human; 1:100
Haller F, Cortis J, Helfrich J, Cameron S, Schüler P, Schwager S, et al. Epithelioid/mixed phenotype in gastrointestinal stromal tumors with KIT mutation from the stomach is associated with accelerated passage of late phases of the cell cycle and shorter disease-free survival. Mod Pathol. 2011;24:248-55 pubmed publisher
  • immunohistochemistry; human; 1:40
Schmid S, Tinguely M, Cione P, Moch H, Bode B. Flow cytometry as an accurate tool to complement fine needle aspiration cytology in the diagnosis of low grade malignant lymphomas. Cytopathology. 2011;22:397-406 pubmed publisher
  • immunohistochemistry; human
Christian B, Zhao W, Hamadani M, Sotomayor E, Navarro W, Devine S, et al. Mantle cell lymphoma 12 years after allogeneic bone marrow transplantation occurring simultaneously in recipient and donor. J Clin Oncol. 2010;28:e629-32 pubmed publisher
  • immunohistochemistry; human
Gladkikh A, Potashnikova D, Korneva E, Khudoleeva O, Vorobjev I. Cyclin D1 expression in B-cell lymphomas. Exp Hematol. 2010;38:1047-57 pubmed publisher
  • western blot; mouse; 1:1000
Feuerborn A, Srivastava P, Küffer S, Grandy W, Sijmonsma T, Gretz N, et al. The Forkhead factor FoxQ1 influences epithelial differentiation. J Cell Physiol. 2011;226:710-9 pubmed publisher
  • immunohistochemistry; human; 1:50
Quinn J, Glassford J, Percy L, Munson P, Marafioti T, Rodriguez Justo M, et al. APRIL promotes cell-cycle progression in primary multiple myeloma cells: influence of D-type cyclin group and translocation status. Blood. 2011;117:890-901 pubmed publisher
  • western blot; human; 1:2500
Nelson A, Holt J. Impact of RING and BRCT domain mutations on BRCA1 protein stability, localization and recruitment to DNA damage. Radiat Res. 2010;174:1-13 pubmed publisher
  • immunohistochemistry; mouse
Lee G, Goretsky T, Managlia E, Dirisina R, Singh A, Brown J, et al. Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis. Gastroenterology. 2010;139:869-81, 881.e1-9 pubmed publisher
  • western blot; human
Lui V, Lau C, Ho K, Ng M, Cheng S, Tsao S, et al. Anti-invasion, anti-proliferation and anoikis-sensitization activities of lapatinib in nasopharyngeal carcinoma cells. Invest New Drugs. 2011;29:1241-52 pubmed publisher
  • immunohistochemistry; human; 1:100
Jung C, Kang Y, Bae J, Lim D, Choi Y, Lee K. Unique patterns of tumor growth related with the risk of lymph node metastasis in papillary thyroid carcinoma. Mod Pathol. 2010;23:1201-8 pubmed publisher
  • immunocytochemistry; human; 1:50
Hitomi M, Stacey D. The checkpoint kinase ATM protects against stress-induced elevation of cyclin D1 and potential cell death in neurons. Cytometry A. 2010;77:524-33 pubmed publisher
  • immunohistochemistry; human; 1:100
Hong A, Dobbins T, Lee C, Jones D, Fei J, Clark J, et al. Use of cyclin D1 in conjunction with human papillomavirus status to predict outcome in oropharyngeal cancer. Int J Cancer. 2011;128:1532-45 pubmed publisher
  • immunohistochemistry; human; 1:50
Karim R, Gerega S, Yang Y, Spillane A, Carmalt H, Scolyer R, et al. p16 and pRb immunohistochemical expression increases with increasing tumour grade in mammary phyllodes tumours. Histopathology. 2010;56:868-75 pubmed publisher
  • immunohistochemistry; human; 1:100
Schor A, Moraes M, Bisson F, Bisson M, Luiz O, Bacchi C. Primary plasmacytoma of the cervix in a 21-year-old female patient. Int J Gynecol Pathol. 2010;29:290-3 pubmed publisher
  • immunohistochemistry; human; 1:50
de Vicente J, Torre Iturraspe A, Gutiérrez A, Lequerica Fernandez P. Immunohistochemical comparative study of the odontogenic keratocysts and other odontogenic lesions. Med Oral Patol Oral Cir Bucal. 2010;15:e709-15 pubmed
  • immunohistochemistry; human; 1:50
Hakim S, Kosmehl H, Sieg P, Trenkle T, Jacobsen H, Attila Benedek G, et al. Altered expression of cell-cell adhesion molecules ?-catenin/E-cadherin and related Wnt-signaling pathway in sporadic and syndromal keratocystic odontogenic tumors. Clin Oral Investig. 2011;15:321-8 pubmed publisher
  • immunohistochemistry; human; 1:20
Levidou G, Saetta A, Karlou M, Thymara I, Pratsinis H, Pavlopoulos P, et al. D-type cyclins in superficial and muscle-invasive bladder urothelial carcinoma: correlation with clinicopathological data and prognostic significance. J Cancer Res Clin Oncol. 2010;136:1563-71 pubmed publisher
  • immunohistochemistry; human
Brezillon S, Zeltz C, Schneider L, Terryn C, Vuillermoz B, Ramont L, et al. Lumican inhibits B16F1 melanoma cell lung metastasis. J Physiol Pharmacol. 2009;60 Suppl 4:15-22 pubmed
  • immunohistochemistry; human; 1:100
Metcalf R, Zhao S, Anderson M, Lu Z, Galperin I, Marinelli R, et al. Characterization of D-cyclin proteins in hematolymphoid neoplasms: lack of specificity of cyclin-D2 and D3 expression in lymphoma subtypes. Mod Pathol. 2010;23:420-33 pubmed publisher
  • immunohistochemistry; human; 1:50
Perrotto J, Abbott J, Ceilley R, Ahmed I. The role of immunohistochemistry in discriminating primary from secondary extramammary Paget disease. Am J Dermatopathol. 2010;32:137-43 pubmed publisher
  • immunohistochemistry; human; 1:50
Aamodt R, Jonsdottir K, Andersen S, Bondi J, Bukholm G, Bukholm I. Differences in protein expression and gene amplification of cyclins between colon and rectal adenocarcinomas. Gastroenterol Res Pract. 2009;2009:285830 pubmed publisher
  • immunohistochemistry - paraffin section; human; tbl 1
Leong A, Haffajee Z. Citraconic anhydride: a new antigen retrieval solution. Pathology. 2010;42:77-81 pubmed publisher
  • immunohistochemistry; human; 1:100
Alberghini M, Kliskey K, Krenacs T, Picci P, Kindblom L, Forsyth R, et al. Morphological and immunophenotypic features of primary and metastatic giant cell tumour of bone. Virchows Arch. 2010;456:97-103 pubmed publisher
  • immunohistochemistry; human; 1:50
Quinn J, Percy L, Glassford J, Somana K, Rodriguez Justo M, Yong K. CD20-positive multiple myeloma - differential expression of cyclins D1 and D2 suggests a heterogeneous disease. Br J Haematol. 2010;149:156-9 pubmed publisher
  • immunohistochemistry; human
Huang Y, de Reynies A, de Leval L, Ghazi B, Martin Garcia N, Travert M, et al. Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal type. Blood. 2010;115:1226-37 pubmed publisher
  • immunohistochemistry; mouse
Laine H, Sulg M, Kirjavainen A, Pirvola U. Cell cycle regulation in the inner ear sensory epithelia: role of cyclin D1 and cyclin-dependent kinase inhibitors. Dev Biol. 2010;337:134-46 pubmed publisher
  • immunohistochemistry; human; 1:50
Garcia C, Hunt K, Kang H, Babb A, Gale J, Vasef M, et al. Most morphologic features in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) do not reliably predict underlying FISH genetics or immunoglobulin heavy chain variable region somatic mutational status. Appl Immunohistochem Mol Morphol. 2010;18:119-27 pubmed publisher
  • immunohistochemistry; human; 1:2000
Stefancikova L, Moulis M, Fabian P, Falkova I, Vasova I, Kren L, et al. Complex analysis of cyclin D1 expression in mantle cell lymphoma: two cyclin D1-negative cases detected. J Clin Pathol. 2009;62:948-50 pubmed publisher
  • western blot; human; 1:1000
Huesca M, Lock L, Khine A, Viau S, Peralta R, Cukier I, et al. A novel small molecule with potent anticancer activity inhibits cell growth by modulating intracellular labile zinc homeostasis. Mol Cancer Ther. 2009;8:2586-96 pubmed publisher
  • immunohistochemistry; human; fig 3
Italiano A, Bianchini L, Gjernes E, Keslair F, Ranchere Vince D, Dumollard J, et al. Clinical and biological significance of CDK4 amplification in well-differentiated and dedifferentiated liposarcomas. Clin Cancer Res. 2009;15:5696-703 pubmed publisher
  • immunohistochemistry; human
Mangseth K, Helgeland L, Klos J, Molven A, Vintermyr O. Improved diagnostic segregation of mantle cell lymphoma by determination of cyclin D1/D3 expression ratio in formalin-fixed tissue. Diagn Mol Pathol. 2009;18:150-5 pubmed publisher
  • immunohistochemistry; human; 1:100
Cheuk W, Lee K, Chong L, Yuen S, Chan J. IgG4-related Sclerosing disease: a potential new etiology of cutaneous pseudolymphoma. Am J Surg Pathol. 2009;33:1713-9 pubmed publisher
  • immunohistochemistry; human
Horváth E, Mezei T, Pávai Z, Turcu M, Demian S, Toth E, et al. Diagnostic and differential diagnostic criteria of lymphoid neoplasms in bone marrow trephine biopsies: a study of 87 cases. Rom J Morphol Embryol. 2009;50:399-406 pubmed
  • immunohistochemistry; human
Myong N. Cyclin D1 overexpression, p16 loss, and pRb inactivation play a key role in pulmonary carcinogenesis and have a prognostic implication for the long-term survival in non-small cell lung carcinoma patients. Cancer Res Treat. 2008;40:45-52 pubmed publisher
  • immunohistochemistry; human; 1:100
Karim R, Li W, Sanki A, Colman M, Yang Y, Thompson J, et al. Reduced p16 and increased cyclin D1 and pRb expression are correlated with progression in cutaneous melanocytic tumors. Int J Surg Pathol. 2009;17:361-7 pubmed publisher
  • immunohistochemistry; human
Chiu A, Frizzera G, Mathew S, Hyjek E, Chadburn A, Tam W, et al. Diffuse blastoid B-cell lymphoma: a histologically aggressive variant of t(14;18)-negative follicular lymphoma. Mod Pathol. 2009;22:1507-17 pubmed publisher
  • immunohistochemistry; human
Quintanilla Martinez L, Slotta Huspenina J, Koch I, Klier M, Hsi E, de Leval L, et al. Differential diagnosis of cyclin D2+ mantle cell lymphoma based on fluorescence in situ hybridization and quantitative real-time-PCR. Haematologica. 2009;94:1595-8 pubmed publisher
  • immunohistochemistry; human; 1:50
D Angelo E, Spagnoli L, Prat J. Comparative clinicopathologic and immunohistochemical analysis of uterine sarcomas diagnosed using the World Health Organization classification system. Hum Pathol. 2009;40:1571-85 pubmed publisher
  • immunohistochemistry; human; 1:100
Park Y, Kim Y, Lee Y, Kim S, Park S, Kim K, et al. Papillary microcarcinoma in comparison with larger papillary thyroid carcinoma in BRAF(V600E) mutation, clinicopathological features, and immunohistochemical findings. Head Neck. 2010;32:38-45 pubmed publisher
  • immunohistochemistry; human; 1:25
Mitrovic Z, Ilic I, Nola M, Aurer I, Sonicki Z, Basic Kinda S, et al. CD43 expression is an adverse prognostic factor in diffuse large B-Cell lymphoma. Clin Lymphoma Myeloma. 2009;9:133-7 pubmed publisher
  • western blot; human
Mamaghani S, Patel S, Hedley D. Glycogen synthase kinase-3 inhibition disrupts nuclear factor-kappaB activity in pancreatic cancer, but fails to sensitize to gemcitabine chemotherapy. BMC Cancer. 2009;9:132 pubmed publisher
  • immunohistochemistry; human
Jacquemier J, Charafe Jauffret E, Monville F, Esterni B, Extra J, Houvenaeghel G, et al. Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer. Breast Cancer Res. 2009;11:R23 pubmed publisher
  • immunohistochemistry; human; 1:100
Polotsky A, Zhu L, Santoro N, Pollard J. Lithium chloride treatment induces epithelial cell proliferation in xenografted human endometrium. Hum Reprod. 2009;24:1960-7 pubmed publisher
  • immunohistochemistry; human; 1:40
Luu V, Boysen G, Struckmann K, Casagrande S, von Teichman A, Wild P, et al. Loss of VHL and hypoxia provokes PAX2 up-regulation in clear cell renal cell carcinoma. Clin Cancer Res. 2009;15:3297-304 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Le T, Conley K, Brown N. Jagged 1 is necessary for normal mouse lens formation. Dev Biol. 2009;328:118-26 pubmed publisher
  • immunohistochemistry; human
Sukov W, Ketterling R, Lager D, Carlson A, Sinnwell J, Chow G, et al. CCND1 rearrangements and cyclin D1 overexpression in renal oncocytomas: frequency, clinicopathologic features, and utility in differentiation from chromophobe renal cell carcinoma. Hum Pathol. 2009;40:1296-303 pubmed publisher
  • immunohistochemistry; human; 1:100
Cheuk W, Chan A, Lam W, Chow S, Crowley P, Lloydd R, et al. IgG4-related sclerosing mastitis: description of a new member of the IgG4-related sclerosing diseases. Am J Surg Pathol. 2009;33:1058-64 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Volate S, Muga S, Issa A, Nitcheva D, Smith T, Wargovich M. Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer. Mol Carcinog. 2009;48:920-33 pubmed publisher
  • immunohistochemistry; human; 1:80
Boone J, van Hillegersberg R, Offerhaus G, van Diest P, Borel Rinkes I, ten Kate F. Targets for molecular therapy in esophageal squamous cell carcinoma: an immunohistochemical analysis. Dis Esophagus. 2009;22:496-504 pubmed publisher
  • western blot; human; 1:2000
  • immunohistochemistry; mouse; 1:100
Pysz M, Leontieva O, Bateman N, Uronis J, Curry K, Threadgill D, et al. PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1. Exp Cell Res. 2009;315:1415-28 pubmed publisher
  • western blot; human; fig s4
Rogers S, Box C, Chambers P, Barbachano Y, Nutting C, Rhys Evans P, et al. Determinants of response to epidermal growth factor receptor tyrosine kinase inhibition in squamous cell carcinoma of the head and neck. J Pathol. 2009;218:122-30 pubmed publisher
  • immunohistochemistry; human
Wildeman M, Gibcus J, Hauptmann M, Begg A, van Velthuysen M, Hoebers F, et al. Radiotherapy in laryngeal carcinoma: can a panel of 13 markers predict response?. Laryngoscope. 2009;119:316-22 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 1
  • immunohistochemistry; human
Dawson M, Opat S, Taouk Y, Donovan M, Zammit M, Monaghan K, et al. Clinical and immunohistochemical features associated with a response to bortezomib in patients with multiple myeloma. Clin Cancer Res. 2009;15:714-22 pubmed publisher
  • immunohistochemistry; human; 1:250
Gibson S, Hsi E. Epstein-Barr virus-positive B-cell lymphoma of the elderly at a United States tertiary medical center: an uncommon aggressive lymphoma with a nongerminal center B-cell phenotype. Hum Pathol. 2009;40:653-61 pubmed publisher
  • immunohistochemistry; mouse; 1:75
Patil M, Lee S, Macias E, Lam E, Xu C, Jones K, et al. Role of cyclin D1 as a mediator of c-Met- and beta-catenin-induced hepatocarcinogenesis. Cancer Res. 2009;69:253-61 pubmed publisher
  • immunohistochemistry; human
Kelley T, Baz R, Hussein M, Karafa M, Cook J. Clinical significance of cyclin D1, fibroblast growth factor receptor 3, and p53 immunohistochemistry in plasma cell myeloma treated with a thalidomide-based regimen. Hum Pathol. 2009;40:405-12 pubmed publisher
  • immunohistochemistry; human
Naushad H, Choi W, Page C, Sanger W, Weisenburger D, Aoun P. Mantle cell lymphoma with flow cytometric evidence of clonal plasmacytic differentiation: a case report. Cytometry B Clin Cytom. 2009;76:218-24 pubmed publisher
  • immunohistochemistry; human; 1:50
Da Silva L, Buck L, Simpson P, Reid L, McCallum N, Madigan B, et al. Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis. Virchows Arch. 2009;454:107-14 pubmed publisher
  • immunohistochemistry; human; 1:50
Mudhar H, Saunders E, Rundle P, Rennie I, Sisley K. The in vivo modulatory effects of an anterior-chamber microenvironment on uveal melanoma. Br J Ophthalmol. 2009;93:535-40 pubmed publisher
  • immunohistochemistry; mouse
Jin L, Burniat A, Dumont J, Miot F, Corvilain B, Franc B. Human thyroid tumours, the puzzling lessons from E7 and RET/PTC3 transgenic mice. Br J Cancer. 2008;99:1874-83 pubmed publisher
  • immunohistochemistry; human; 1:50
van Dekken H, Hop W, Tilanus H, Haringsma J, van der Valk H, Wink J, et al. Immunohistochemical evaluation of a panel of tumor cell markers during malignant progression in Barrett esophagus. Am J Clin Pathol. 2008;130:745-53 pubmed publisher
  • immunohistochemistry; human
Cinti C, Vindigni C, Zamparelli A, La Sala D, Epistolato M, Marrelli D, et al. Activated Akt as an indicator of prognosis in gastric cancer. Virchows Arch. 2008;453:449-55 pubmed publisher
  • immunohistochemistry; human; 1:100
Huang H, West R, Tzeng C, van de Rijn M, Wang J, Chou S, et al. Immunohistochemical and biogenetic features of diffuse-type tenosynovial giant cell tumors: the potential roles of cyclin A, P53, and deletion of 15q in sarcomatous transformation. Clin Cancer Res. 2008;14:6023-32 pubmed publisher
  • immunohistochemistry; human; 1:50
Gaumann A, Bode Lesniewska B, Zimmermann D, Fanburg Smith J, Kirkpatrick C, Hofstadter F, et al. Exploration of the APC/beta-catenin (WNT) pathway and a histologic classification system for pulmonary artery intimal sarcoma. A study of 18 cases. Virchows Arch. 2008;453:473-84 pubmed publisher
  • immunohistochemistry; human; 1:50
Lagoo A, Haggerty C, Kim Y, Hammons M, Neufeld K, Redher C, et al. Morphologic features of 115 lymphomas of the orbit and ocular adnexa categorized according to the World Health Organization classification: are marginal zone lymphomas in the orbit mucosa-associated lymphoid tissue-type lymphomas?. Arch Pathol Lab Med. 2008;132:1405-16 pubmed publisher
  • immunohistochemistry; mouse; 1:200
Svärd J, Rozell B, Toftgard R, Teglund S. Tumor suppressor gene co-operativity in compound Patched1 and suppressor of fused heterozygous mutant mice. Mol Carcinog. 2009;48:408-19 pubmed publisher
  • immunohistochemistry; human
Wang X, Asplund A, Porwit A, Flygare J, Smith C, Christensson B, et al. The subcellular Sox11 distribution pattern identifies subsets of mantle cell lymphoma: correlation to overall survival. Br J Haematol. 2008;143:248-52 pubmed publisher
  • immunohistochemistry; human; 1:50
Bertolo C, Guerrero D, Vicente F, Cordoba A, Esteller M, Ropero S, et al. Differences and molecular immunohistochemical parameters in the subtypes of infiltrating ductal breast cancer. Am J Clin Pathol. 2008;130:414-24 pubmed publisher
  • immunohistochemistry; mouse; 1:25
Brellier F, Bergoglio V, Valin A, Barnay S, Chevallier Lagente O, Vielh P, et al. Heterozygous mutations in the tumor suppressor gene PATCHED provoke basal cell carcinoma-like features in human organotypic skin cultures. Oncogene. 2008;27:6601-6 pubmed publisher
  • immunohistochemistry; human; 1:50
Carney J, Stratakis C. Stromal, fibrous, and fatty gastrointestinal tumors in a patient with a PDGFRA gene mutation. Am J Surg Pathol. 2008;32:1412-20 pubmed publisher
  • western blot; human
Neuwirt H, Arias M, Puhr M, Hobisch A, Culig Z. Oligomeric proanthocyanidin complexes (OPC) exert anti-proliferative and pro-apoptotic effects on prostate cancer cells. Prostate. 2008;68:1647-54 pubmed publisher
  • immunohistochemistry; human; 1:100
Bozzi F, Ferrari A, Negri T, Conca E, Luca D, Losa M, et al. Molecular characterization of synovial sarcoma in children and adolescents: evidence of akt activation. Transl Oncol. 2008;1:95-101 pubmed
  • immunohistochemistry - frozen section; mouse; 1:100; fig 6
Rowan S, Conley K, Le T, Donner A, Maas R, Brown N. Notch signaling regulates growth and differentiation in the mammalian lens. Dev Biol. 2008;321:111-22 pubmed publisher
  • immunohistochemistry; human; 1:50
Hunt K, Reichard K, Wilson C. Mantle cell lymphoma lacking the t(11;14) translocation: a case report and brief review of the literature. J Clin Pathol. 2008;61:869-70 pubmed publisher
  • immunohistochemistry; mouse; 1:500
  • western blot; mouse; 1:500
Koeller H, Ross M, Glickstein S. Cyclin D1 in excitatory neurons of the adult brain enhances kainate-induced neurotoxicity. Neurobiol Dis. 2008;31:230-41 pubmed publisher
  • immunohistochemistry; human
Ioannou M, Stathakis E, Lazaris A, Papathomas T, Tsiambas E, Koukoulis G. Immunohistochemical evaluation of 95 bone marrow reactive plasmacytoses. Pathol Oncol Res. 2009;15:25-9 pubmed publisher
  • immunohistochemistry; human
Alatas N, Baba F. Proliferating active cells, lymphocyte subsets, and dendritic cells in recurrent tonsillitis: their effect on hypertrophy. Arch Otolaryngol Head Neck Surg. 2008;134:477-83 pubmed publisher
  • immunohistochemistry; human; 1:50
Marchio C, Iravani M, Natrajan R, Lambros M, Savage K, Tamber N, et al. Genomic and immunophenotypical characterization of pure micropapillary carcinomas of the breast. J Pathol. 2008;215:398-410 pubmed publisher
  • immunohistochemistry; human; 1:40
Huh Y, Lin K, Vega F, Schlette E, Yin C, Keating M, et al. MYC translocation in chronic lymphocytic leukaemia is associated with increased prolymphocytes and a poor prognosis. Br J Haematol. 2008;142:36-44 pubmed publisher
  • immunohistochemistry; human; 1:100
Haller F, Löbke C, Ruschhaupt M, Cameron S, Schulten H, Schwager S, et al. Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs). J Pathol. 2008;215:253-62 pubmed publisher
  • immunohistochemistry; human; 1:100
Yi Y, Nowak N, Pacchia A, Morrison C. Chromosome 11 genomic changes in parathyroid adenoma and hyperplasia: array CGH, FISH, and tissue microarrays. Genes Chromosomes Cancer. 2008;47:639-48 pubmed publisher
  • immunohistochemistry; human; 1:75
Yang C, Hung W, Wang S, Kang W, Chen W, Huang Y, et al. Immunoexpression and prognostic role of hTERT and cyclin D1 in urothelial carcinoma. APMIS. 2008;116:309-16 pubmed publisher
  • immunohistochemistry; human; 1:100
Min H, Choe G, Kim S, Park Y, Park D, Youn Y, et al. S100A4 expression is associated with lymph node metastasis in papillary microcarcinoma of the thyroid. Mod Pathol. 2008;21:748-55 pubmed publisher
  • immunohistochemistry; human
Bink K, Haralambieva E, Kremer M, Ott G, Beham Schmid C, de Leval L, et al. Primary extramedullary plasmacytoma: similarities with and differences from multiple myeloma revealed by interphase cytogenetics. Haematologica. 2008;93:623-6 pubmed publisher
  • immunohistochemistry; human; 1:50
Eigeliene N, Härkönen P, Erkkola R. Effects of estradiol and medroxyprogesterone acetate on expression of the cell cycle proteins cyclin D1, p21 and p27 in cultured human breast tissues. Cell Cycle. 2008;7:71-80 pubmed
  • immunohistochemistry; human; 1:100
Audard V, Cavard C, Richa H, Infante M, Couvelard A, Sauvanet A, et al. Impaired E-cadherin expression and glutamine synthetase overexpression in solid pseudopapillary neoplasm of the pancreas. Pancreas. 2008;36:80-3 pubmed publisher
  • immunohistochemistry; human; 1:100
Aronica E, Boer K, Becker A, Redeker S, Spliet W, van Rijen P, et al. Gene expression profile analysis of epilepsy-associated gangliogliomas. Neuroscience. 2008;151:272-92 pubmed
  • immunohistochemistry; mouse
Kubota Y, Takubo K, Suda T. Bone marrow long label-retaining cells reside in the sinusoidal hypoxic niche. Biochem Biophys Res Commun. 2008;366:335-9 pubmed
  • western blot; rat
Xie T, Niu Y, Ge K, Lu S. Regulation of keratinocyte proliferation in rats with deep, partial-thickness scald: modulation of cyclin D1-cyclin-dependent kinase 4 and histone H1 kinase activity of M-phase promoting factor. J Surg Res. 2008;147:9-14 pubmed
  • immunohistochemistry; mouse; 1:5000
Glickstein S, Moore H, Slowinska B, Racchumi J, Suh M, Chuhma N, et al. Selective cortical interneuron and GABA deficits in cyclin D2-null mice. Development. 2007;134:4083-93 pubmed
  • immunohistochemistry; human; 1:50
Tan D, Marchio C, Jones R, Savage K, Smith I, Dowsett M, et al. Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients. Breast Cancer Res Treat. 2008;111:27-44 pubmed
  • immunohistochemistry; human
He H, Cheng L, Weiss L, Chu P. Clinical outcome of incidental pelvic node malignant B-cell lymphomas discovered at the time of radical prostatectomy. Leuk Lymphoma. 2007;48:1976-80 pubmed
  • immunohistochemistry; rat; 1:200
Vogetseder A, Picard N, Gaspert A, Walch M, Kaissling B, Le Hir M. Proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells. Am J Physiol Cell Physiol. 2008;294:C22-8 pubmed
  • immunohistochemistry; human; 1:100
Melck A, Masoudi H, Griffith O, Rajput A, Wilkins G, Bugis S, et al. Cell cycle regulators show diagnostic and prognostic utility for differentiated thyroid cancer. Ann Surg Oncol. 2007;14:3403-11 pubmed
  • immunohistochemistry; human; 1:100
Demirkan N, Kesen Z, Akdag B, Larue L, Delmas V. The effect of the sun on expression of beta-catenin, p16 and cyclin d1 proteins in melanocytic lesions. Clin Exp Dermatol. 2007;32:733-9 pubmed
  • immunohistochemistry; human; 1:75
El Demellawy D, Ross C, Sur M, Alowami S. Synchronously diagnosed lymph nodal collision tumor of malignant melanoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: case report. Diagn Pathol. 2007;2:34 pubmed
  • immunohistochemistry; human; 1:100
Park Y, Kwak S, Kim D, Kim H, Choe G, Park D, et al. Diagnostic value of galectin-3, HBME-1, cytokeratin 19, high molecular weight cytokeratin, cyclin D1 and p27(kip1) in the differential diagnosis of thyroid nodules. J Korean Med Sci. 2007;22:621-8 pubmed
  • immunohistochemistry; human; 1:100
Farmer P, Bailey D, Burns B, Day A, LeBrun D. The reliability of lymphoma diagnosis in small tissue samples is heavily influenced by lymphoma subtype. Am J Clin Pathol. 2007;128:474-80 pubmed
  • immunohistochemistry; human; 1:30
Papadopoulos O, Betsi E, Tsakistou G, Frangoulis M, Fangoulis M, Kouvatseas G, et al. Expression of cyclin D1 and Ki-67 in squamous cell carcinoma of the penis. Anticancer Res. 2007;27:2167-74 pubmed
  • immunohistochemistry; human; 1:50
de Roos M, van der Vegt B, Peterse J, Patriarca C, De Vries J, de Bock G, et al. The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome in 'pure' ductal carcinoma in situ of the breast. Histopathology. 2007;51:227-38 pubmed
  • immunohistochemistry; human; 1:50
van der Vegt B, de Roos M, Peterse J, Patriarca C, Hilkens J, de Bock G, et al. The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome of invasive ductal breast carcinoma. Histopathology. 2007;51:322-35 pubmed
  • immunohistochemistry; human; 1:50
Wong S, Chan J, Lo E, Chan A, Wong M, Chan C, et al. The contribution of bifunctional SkipDewax pretreatment solution, rabbit monoclonal antibodies, and polymer detection systems in immunohistochemistry. Arch Pathol Lab Med. 2007;131:1047-55 pubmed
  • immunohistochemistry; human; 1:50
Filipits M, Pirker R, Dunant A, Lantuejoul S, Schmid K, Huynh A, et al. Cell cycle regulators and outcome of adjuvant cisplatin-based chemotherapy in completely resected non-small-cell lung cancer: the International Adjuvant Lung Cancer Trial Biologic Program. J Clin Oncol. 2007;25:2735-40 pubmed
  • immunohistochemistry; human; 1:100
Papay J, Krenacs T, Moldvay J, Stelkovics E, Furak J, Molnar B, et al. Immunophenotypic profiling of nonsmall cell lung cancer progression using the tissue microarray approach. Appl Immunohistochem Mol Morphol. 2007;15:19-30 pubmed
  • immunohistochemistry; human; 1:100
Demirkan N, Bir F, Erdem O, Duzcan E. Immunohistochemical expression of beta-catenin, E-cadherin, cyclin D1 and c-myc in benign trichogenic tumors. J Cutan Pathol. 2007;34:467-73 pubmed
  • immunohistochemistry; human; 1:100
Aronica E, Boer K, Baybis M, Yu J, Crino P. Co-expression of cyclin D1 and phosphorylated ribosomal S6 proteins in hemimegalencephaly. Acta Neuropathol. 2007;114:287-93 pubmed
  • immunohistochemistry; human; 1:50
Phuoc N, Ehara H, Gotoh T, Nakano M, Yokoi S, Deguchi T, et al. Immunohistochemical analysis with multiple antibodies in search of prognostic markers for clear cell renal cell carcinoma. Urology. 2007;69:843-8 pubmed
  • immunohistochemistry; human; 1:50
Li W, Tran N, Lee S, O Brien C, Tse G, Scolyer R, et al. New evidence for geographic variation in the role of human papillomavirus in tonsillar carcinogenesis. Pathology. 2007;39:217-22 pubmed
  • immunohistochemistry; human; 1:200
van Dekken H, Wink J, Vissers K, Franken P, Ruud Schouten W, J Hop W, et al. Wnt pathway-related gene expression during malignant progression in ulcerative colitis. Acta Histochem. 2007;109:266-72 pubmed
  • western blot; mouse; 1:1000
Okano J, Suzuki S, Shiota K. Involvement of apoptotic cell death and cell cycle perturbation in retinoic acid-induced cleft palate in mice. Toxicol Appl Pharmacol. 2007;221:42-56 pubmed
  • immunohistochemistry; human; 1:100
Mansoor A, Akbari M, Auer I, Lai R. Cyclin D1 and t(11;14)-positive B-cell neoplasms resembling marginal zone B-cell lymphoma: a morphological variant of mantle cell lymphoma. Hum Pathol. 2007;38:797-802 pubmed
  • immunohistochemistry; human
Guglielmelli T, Giugliano E, Cappia S, Papotti M, Saglio G. Frequency and distribution of trisomy 11 in multiple myeloma patients: relation with overexpression of CCND1 and t(11;14). Cancer Genet Cytogenet. 2007;173:51-6 pubmed
  • immunohistochemistry; human; 1:75
Wang S, Chen W, Li S, Li S, Yang S, Chai C. Expression of human telomerase reverse transcriptase and cyclin-D1 in olfactory neuroblastoma. APMIS. 2007;115:17-21 pubmed
  • immunohistochemistry; baboons; 1:80
Dumitrescu A, Aberdeen G, Pepe G, Albrecht E. Developmental expression of cell cycle regulators in the baboon fetal adrenal gland. J Endocrinol. 2007;192:237-47 pubmed
  • immunohistochemistry; human; 1:40
Huh Y, Abruzzo L, Rassidakis G, Parry Jones N, Schlette E, Brito Bapabulle V, et al. The t(14;19)(q32;q13)-positive small B-cell leukaemia: a clinicopathologic and cytogenetic study of seven cases. Br J Haematol. 2007;136:220-8 pubmed
  • immunohistochemistry; human; 1:50; fig 2
Reis Filho J, Simpson P, Turner N, Lambros M, Jones C, Mackay A, et al. FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. Clin Cancer Res. 2006;12:6652-62 pubmed
  • immunohistochemistry; human; 1:100
Perrone F, Suardi S, Pastore E, Casieri P, Orsenigo M, Caramuta S, et al. Molecular and cytogenetic subgroups of oropharyngeal squamous cell carcinoma. Clin Cancer Res. 2006;12:6643-51 pubmed
  • immunohistochemistry; human; 1:40
Vega F, Padula A, Valbuena J, Stancu M, Jones D, Medeiros L. Lymphomas involving the pleura: a clinicopathologic study of 34 cases diagnosed by pleural biopsy. Arch Pathol Lab Med. 2006;130:1497-502 pubmed
  • immunohistochemistry; human; 1:50
Subramaniam M, Navarro S, Pellin A, Lopez Guerrero J, Carda C, Heredia Alvaro J, et al. Tissue microarray profiling of primary and xenotransplanted synovial sarcomas demonstrates the immunophenotypic similarities existing between SYT-SSX fusion gene confirmed, biphasic, and monophasic fibrous variants. Virchows Arch. 2006;449:435-47 pubmed
  • immunohistochemistry; human
Chuang S, Huang W, Hsieh P, Tseng H, Campo E, Colomer D, et al. Mantle cell lymphoma in Taiwan: clinicopathological and molecular study of 21 cases including one cyclin D1-negative tumor expressing cyclin D2. Pathol Int. 2006;56:440-8 pubmed
  • immunohistochemistry; human; 1:100
Kostopoulos I, Cocco M, Ginanneschi C, D Amuri A, Lazzi S, Fabbri A, et al. Overlapping morphologic and immunophenotypic profiles in small B-cell lymphoma. A report of two cases. Virchows Arch. 2006;449:320-7 pubmed
  • immunohistochemistry; human; 1:100
Handra Luca A, Ruhin B, Lesty C, Fouret P. P27, SKP2, and extra-cellular signal-related kinase signalling in human salivary gland mucoepidermoid carcinoma. Oral Oncol. 2006;42:1005-10 pubmed
  • western blot; human; 1:400
Juhlin C, Larsson C, Yakoleva T, Leibiger I, Leibiger B, Alimov A, et al. Loss of parafibromin expression in a subset of parathyroid adenomas. Endocr Relat Cancer. 2006;13:509-23 pubmed
  • immunohistochemistry; human; 1:250
Cook J, Hsi E, Worley S, Tubbs R, Hussein M. Immunohistochemical analysis identifies two cyclin D1+ subsets of plasma cell myeloma, each associated with favorable survival. Am J Clin Pathol. 2006;125:615-24 pubmed
  • immunohistochemistry; human
Zamo A, Zanotti R, Lestani M, Ott G, Katzenberger T, Scarpa A, et al. Molecular characterization of composite mantle cell and follicular lymphoma. Virchows Arch. 2006;448:639-43 pubmed
  • immunohistochemistry; human; 1:50
Charlotte F, Doghmi K, Cassoux N, Ye H, Du M, Kujas M, et al. Ocular adnexal marginal zone B cell lymphoma: a clinical and pathologic study of 23 cases. Virchows Arch. 2006;448:506-16 pubmed
  • immunohistochemistry; rat
  • western blot; rat
Weroha S, Li S, Tawfik O, Li J. Overexpression of cyclins D1 and D3 during estrogen-induced breast oncogenesis in female ACI rats. Carcinogenesis. 2006;27:491-8 pubmed
  • immunohistochemistry; mouse
Bauer S, Patterson P. The cell cycle-apoptosis connection revisited in the adult brain. J Cell Biol. 2005;171:641-50 pubmed
  • immunohistochemistry; human; 1:100
Torlakovic E, Nielsen S, Vyberg M. Antibody selection in immunohistochemical detection of cyclin D1 in mantle cell lymphoma. Am J Clin Pathol. 2005;124:782-9 pubmed
  • immunohistochemistry; human
Medeiros L, Estrov Z, Rassidakis G. Z-138 cell line was derived from a patient with blastoid variant mantle cell lymphoma. Leuk Res. 2006;30:497-501 pubmed
  • immunohistochemistry - paraffin section; human; 1:40
  • immunohistochemistry; human; 1:15
Konoplev S, Medeiros L, Bueso Ramos C, Jorgensen J, Lin P. Immunophenotypic profile of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia. Am J Clin Pathol. 2005;124:414-20 pubmed
  • immunohistochemistry; rat; 1:150
Siegenthaler J, Miller M. Ethanol disrupts cell cycle regulation in developing rat cortex interaction with transforming growth factor beta1. J Neurochem. 2005;95:902-12 pubmed
  • immunocytochemistry; rat
  • immunohistochemistry; rat; 1:100
Siegenthaler J, Miller M. Transforming growth factor beta 1 promotes cell cycle exit through the cyclin-dependent kinase inhibitor p21 in the developing cerebral cortex. J Neurosci. 2005;25:8627-36 pubmed
  • immunohistochemistry; human; 1:100
Fu K, Weisenburger D, Greiner T, Dave S, Wright G, Rosenwald A, et al. Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling. Blood. 2005;106:4315-21 pubmed
  • immunohistochemistry; mouse
Barisoni L, Madaio M, Eraso M, Gasser D, Nelson P. The kd/kd mouse is a model of collapsing glomerulopathy. J Am Soc Nephrol. 2005;16:2847-51 pubmed
  • western blot; human
Siitonen T, Koistinen P, Savolainen E. Increase in Ara-C cytotoxicity in the presence of valproate, a histone deacetylase inhibitor, is associated with the concurrent expression of cyclin D1 and p27(Kip 1) in acute myeloblastic leukemia cells. Leuk Res. 2005;29:1335-42 pubmed
  • immunohistochemistry; human
  • western blot; human
Kveiborg M, Fröhlich C, Albrechtsen R, Tischler V, Dietrich N, Holck P, et al. A role for ADAM12 in breast tumor progression and stromal cell apoptosis. Cancer Res. 2005;65:4754-61 pubmed
  • immunohistochemistry; human
Sander B, Flygare J, Porwit MacDonald A, Smith C, Emanuelsson E, Kimby E, et al. Mantle cell lymphomas with low levels of cyclin D1 long mRNA transcripts are highly proliferative and can be discriminated by elevated cyclin A2 and cyclin B1. Int J Cancer. 2005;117:418-30 pubmed
  • immunohistochemistry; mouse
Burns J, Abdallah B, Guldberg P, Rygaard J, Schrøder H, Kassem M. Tumorigenic heterogeneity in cancer stem cells evolved from long-term cultures of telomerase-immortalized human mesenchymal stem cells. Cancer Res. 2005;65:3126-35 pubmed
  • immunohistochemistry; human; 1:100
Kovacs G, Stelkovics E, Krenacs L, Gonda G, Goth M, Kovacs L, et al. Low level of cyclin D1 protein expression in thyroid microcarcinomas from an autopsy series. Endocrine. 2005;26:41-4 pubmed
  • western blot; human
Yau T, Chan C, Chan K, Lee M, Wong C, Fan S, et al. HDPR1, a novel inhibitor of the WNT/beta-catenin signaling, is frequently downregulated in hepatocellular carcinoma: involvement of methylation-mediated gene silencing. Oncogene. 2005;24:1607-14 pubmed
Zhang M, Kim S, Yang H. Non-canonical pathway for Rb inactivation and external signaling coordinate cell-cycle entry without CDK4/6 activity. Nat Commun. 2023;14:7847 pubmed publisher
Mohanty A, Nam A, Srivastava S, Jones J, Lomenick B, Singhal S, et al. Acquired resistance to KRAS G12C small-molecule inhibitors via genetic/nongenetic mechanisms in lung cancer. Sci Adv. 2023;9:eade3816 pubmed publisher
Morinaka T, Sakai N, Takayashiki T, Kuboki S, Takano S, Ohira G, et al. RYBP contributes to improved prognosis in colorectal cancer via regulation of cell cycle, apoptosis and oxaliplatin sensitivity. Int J Oncol. 2023;63: pubmed publisher
Li S, Yang M, Zhao R, Peng L, Liu W, Jiang X, et al. Defective EMC1 drives abnormal retinal angiogenesis via Wnt/β-catenin signaling and may be associated with the pathogenesis of familial exudative vitreoretinopathy. Genes Dis. 2023;10:2572-2585 pubmed publisher
Prajapati K, Kumar S. Loss of miR-6844 alters stemness/self-renewal and cancer hallmark(s) markers through CD44-JAK2-STAT3 signaling axis in breast cancer stem-like cells. J Cell Biochem. 2023;124:1186-1202 pubmed publisher
Shuaib M, Kumar S. Induced expression of miR-1250-5p exerts tumor suppressive role in triple-negative breast cancer cells. J Cell Biochem. 2023;124:282-293 pubmed publisher
Shuaib M, Prajapati K, Gupta S, Kumar S. Natural Steroidal Lactone Induces G1/S Phase Cell Cycle Arrest and Intrinsic Apoptotic Pathway by Up-Regulating Tumor Suppressive miRNA in Triple-Negative Breast Cancer Cells. Metabolites. 2022;13: pubmed publisher
Toh E, Baryalai P, Nadeem A, Aung K, Chen S, Persson K, et al. Bacterial protein MakA causes suppression of tumour cell proliferation via inhibition of PIP5K1α/Akt signalling. Cell Death Dis. 2022;13:1024 pubmed publisher
Nakahara M, Fujihara S, Iwama H, Takuma K, Oura K, Tadokoro T, et al. Effect of Lenvatinib treatment on the cell cycle and microRNA profile in hepatocellular carcinoma cells. Biomed Rep. 2022;17:78 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
Cyclin D1 Recombinant Rabbit Monoclonal Antibody (SP4)
Catalog # :
MA5-14512
Quantity :
500 uL
Price :
US 530.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Flow Cytometry: 1:30, Immunocytochemistry: 1:50-1:250, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:25-1:200
Species :
Human, Mouse, Rat
Clone :
SP4
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Cyclin D1 (PRAD-1, bcl-1) is one of the key cell cycle regulators, and functions in association with cdk4 and/or cdk6 by phosphorylating the Rb protein. Cyclin D1 is a putative proto-oncogene overexpressed in a wide variety of human neoplasms including mantle cell lymphomas (MCL). In addition, cyclin D1 positively regulates protein phosphorylation, mammary gland epithelial cell proliferation, and fat cell differentiation. In humans, the CCND1 gene encoding cyclin D1 is present on chromosome 11. Cyclin D1 is a cytoplasmic and nuclear protein that is synthesized during G1 phase and assembles with either cyclin-dependent kinase 4 (CDK4) or CDK6 in response to growth factor stimulation. D-type cyclin-CDK complexes act to inactivate the growth-suppressive function of the Rb protein through its phosphorylation, and titrate CDK inhibitors such as p21Cip1 and p27Kip1. Without growth factor-mediated stimulation, Cyclin D1 is unstable, and undergoes ubiquitin-mediated degradation, which is triggered by its phosphorylation. Cyclin D1 destabilization participates in G1/S phase arrest. The Cyclin D1 protein belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin D1 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. The Cyclin D1 protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. Cyclin D1 has been successfully employed and is a promising tool for further studies in both cell cycle biology and cancer associated abnormalities.
Immunogen :
A synthetic peptide from C-terminus of human cyclin D1
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:30, Immunocytochemistry: 1:50-1:250, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:25-1:200
Aliases :
AI327039; B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; BCL1; BCL-1; BCL-1 oncogene; CCND1; CCND1 protein; cD1; cDNA; CycD1; cyclin D1; Cyl-1; D11S287E; FLJ93625; G1/S-specific cyclin-D1; mRNA; PRAD1; PRAD-1; PRAD1 oncogene; U21B31
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA